ChemicalBook > CAS DataBase List > L-Prolinamide, β-alanyl-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-

L-Prolinamide, β-alanyl-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-

Product Name
L-Prolinamide, β-alanyl-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-
CAS No.
2241643-69-4
Chemical Name
L-Prolinamide, β-alanyl-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-
Synonyms
VH032-C1-NH2;(S,R,S)-AHPC-C2-NH2;L-Prolinamide, β-alanyl-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-;(2S,4R)-1-((S)-2-(3-aminopropanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide;(2S,4R)-1-[(2S)-2-(3-aminopropanamido)-3,3-dimethylbutanoyl]-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide
CBNumber
CB09746754
Molecular Formula
C25H35N5O4S
Formula Weight
501.64
MOL File
2241643-69-4.mol
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L-Prolinamide, β-alanyl-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- Property

Boiling point:
814.5±65.0 °C(Predicted)
Density 
1.258±0.06 g/cm3(Predicted)
pka
14.07±0.40(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
bp-44778
Product name
(S,R,S)-AHPC-C2-NH2
Packaging
100MG
Price
$380
Updated
2026/05/24
BroadPharm
Product number
bp-44778
Product name
(S,R,S)-AHPC-C2-NH2
Packaging
250MG
Price
$650
Updated
2026/05/24
BroadPharm
Product number
bp-44778
Product name
(S,R,S)-AHPC-C2-NH2
Packaging
500MG
Price
$980
Updated
2026/05/24
BroadPharm
Product number
bp-44778
Product name
(S,R,S)-AHPC-C2-NH2
Packaging
1G
Price
$1550
Updated
2026/05/24
ACHEMBLOCK
Product number
W171937
Product name
(2S,4R)-1-((S)-2-(3-aminopropanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Purity
95%
Packaging
500MG
Price
$1345
Updated
2026/05/27
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L-Prolinamide, β-alanyl-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- Chemical Properties,Usage,Production

Uses

(S,R,S)-AHPC-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used inPROTACtechnology[1].

IC 50

VHL

References

[1] Scheepstra M, et al. Bivalent Ligands for Protein Degradation in Drug Discovery.Comput Struct Biotechnol J. 2019;17:160-176. Published 2019 Jan 25. DOI:10.1016/j.csbj.2019.01.006
[2] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. DOI:10.7554/eLife.57277

L-Prolinamide, β-alanyl-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- Preparation Products And Raw materials

Raw materials

Preparation Products

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L-Prolinamide, β-alanyl-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- Suppliers

China 6 Global 6
HANGZHOU LAURET BIOTECHOLOGY CO.,LTD
Tel
15306536782
Email
3839324846@qq.com
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China
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Daicel Chiral Technologies (China)CO.,LTD
Tel
021-50460086-9 15921403865
Fax
+86-21-50462321
Email
han_yajun@dctc.daicel.com
Country
China
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Jilin Province Woda Biotechnology Co., Ltd.
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13504435624
Email
1927928688@qq.com
Country
China
ProdList
1639
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58
Henan Mengtai Pharmaceutical Technology Co., Ltd
Tel
17634413542 17634854698;
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1959525201@qq.com
Country
China
ProdList
9997
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Dipag (Weinan) Biotechnology Co., Ltd
Tel
15114901355
Fax
029-85310852
Email
1002921772@qq.com
Country
China
ProdList
190
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ChemShuttle, Inc.
Tel
83588313 18800520310
Email
sales@chemshuttle.com
Country
China
ProdList
4999
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58

2241643-69-4, L-Prolinamide, β-alanyl-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-Related Search:

(S)-tert-butyl 2-((1R,2R)-3-((1S,2R)-1-hydroxy-1-phenylpropan-2-ylamino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate (S,R,S)-AHPC-PEG2-acid Mal-PEG8-acid 2-(2,6-dioxopiperidin-3-yl)-5-(piperazin-1-yl)-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride

  • (2S,4R)-1-((S)-2-(3-aminopropanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
  • (S,R,S)-AHPC-C2-NH2
  • VH032-C1-NH2
  • (2S,4R)-1-[(2S)-2-(3-aminopropanamido)-3,3-dimethylbutanoyl]-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide
  • L-Prolinamide, β-alanyl-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-
  • 2241643-69-4