ChemicalBook > CAS DataBase List > 4-(2-PYRROLIDIN-1-YL-ETHOXY)-PHENYLAMINE

4-(2-PYRROLIDIN-1-YL-ETHOXY)-PHENYLAMINE

Product Name
4-(2-PYRROLIDIN-1-YL-ETHOXY)-PHENYLAMINE
CAS No.
50609-01-3
Chemical Name
4-(2-PYRROLIDIN-1-YL-ETHOXY)-PHENYLAMINE
Synonyms
)ethoxy]aniL;4-[2-(1-PyrroL;4-(2-(Pyrrolidin-1-yl);4-(2-Pyrrolidinoethoxy)aniline;4-(2-(PYRROLIDIN-1-YL)ETHOXY)ANILINE;4-(2-PYRROLIDIN-1-YL-ETHOXY)-PHENYLAMINE;BenzenaMine, 4-[2-(1-pyrrolidinyl)ethoxy]-
CBNumber
CB11010449
Molecular Formula
C12H18N2O
Formula Weight
206.28
MOL File
50609-01-3.mol
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4-(2-PYRROLIDIN-1-YL-ETHOXY)-PHENYLAMINE Property

Boiling point:
362.2±22.0 °C(Predicted)
Density 
1.097±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
9.76±0.20(Predicted)
Appearance
Light brown to brown Oil
InChI
InChI=1S/C12H18N2O/c13-11-3-5-12(6-4-11)15-10-9-14-7-1-2-8-14/h3-6H,1-2,7-10,13H2
InChIKey
OTYZNDKWNPQQJP-UHFFFAOYSA-N
SMILES
C1(N)=CC=C(OCCN2CCCC2)C=C1
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Safety

HazardClass 
IRRITANT
HS Code 
2921410090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H311Toxic in contact with skin

H317May cause an allergic skin reaction

H318Causes serious eye damage

H331Toxic if inhaled

H341Suspected of causing genetic defects

H351Suspected of causing cancer

H400Very toxic to aquatic life

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P272Contaminated work clothing should not be allowed out of the workplace.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P281Use personal protective equipment as required.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P310Immediately call a POISON CENTER or doctor/physician.

P311Call a POISON CENTER or doctor/physician.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P361Remove/Take off immediately all contaminated clothing.

P363Wash contaminated clothing before reuse.

P391Collect spillage. Hazardous to the aquatic environment

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Matrix Scientific
Product number
033869
Product name
4-(2-Pyrrolidin-1-yl-ethoxy)-phenylamine
Packaging
500mg
Price
$220
Updated
2021/12/16
Activate Scientific
Product number
AS3798
Product name
4-(2-Pyrrolidin-1-yl-ethoxy)-phenylamine
Purity
95+%
Packaging
1g
Price
$263
Updated
2021/12/16
Matrix Scientific
Product number
033869
Product name
4-(2-Pyrrolidin-1-yl-ethoxy)-phenylamine
Packaging
1g
Price
$338
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0024411
Product name
4-(2-PYRROLIDIN-1-YL-ETHOXY)-PHENYLAMINE
Purity
95.00%
Packaging
1G
Price
$696.15
Updated
2021/12/16
SynQuest Laboratories
Product number
4H30-1-8V
Product name
4-(2-(Pyrrolidin-1-yl)ethoxy)aniline
Packaging
1g
Price
$797
Updated
2021/12/16
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4-(2-PYRROLIDIN-1-YL-ETHOXY)-PHENYLAMINE Chemical Properties,Usage,Production

Synthesis

265654-77-1

50609-01-3

General procedure for the synthesis of 4-[2-(pyrrolidin-1-yl)ethoxy]aniline from 1-(2-(4-nitrophenoxy)ethyl)pyrrolidine: 1-[2-(4-nitrophenoxy)ethyl]pyrrolidine (purchased from CombiBlocks, LLC, 5.00 g, 0.0212 mol) was dissolved in 100 mL of methanol and 0.5 g of 10% Pd/C catalyst, and the hydrogenation reaction was carried out under a hydrogen atmosphere (using a balloon to provide hydrogen pressure) and the reaction continued overnight. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated to dryness, the resulting product was used directly in the next step of the reaction without further purification (Yield: 4.36 g, Yield: 99.88%). Spectral analysis of the product showed LCMS (M + H) 207.4.

References

[1] Patent: WO2009/64835, 2009, A1. Location in patent: Page/Page column 168
[2] Patent: WO2004/26823, 2004, A1. Location in patent: Page 36
[3] Patent: WO2016/34642, 2016, A1. Location in patent: Page/Page column 35
[4] Patent: US2015/336982, 2015, A1. Location in patent: Paragraph 0155; 0157
[5] Journal of Organic Chemistry, 1951, vol. 16, p. 1421,1424

4-(2-PYRROLIDIN-1-YL-ETHOXY)-PHENYLAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-(2-PYRROLIDIN-1-YL-ETHOXY)-PHENYLAMINE manufacturers

Jinan Ruitong Biotech Co., Ltd.
Product
[4-[2-(Pyrrolidin-1-yl)ethoxy]phenyl]amine 50609-01-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1
Release date
2025-08-29