ChemicalBook > CAS DataBase List > (R)-2-Amino-2-(4-fluorophenyl)ethanol

(R)-2-Amino-2-(4-fluorophenyl)ethanol

Product Name: (R)-2-Amino-2-(4-fluorophenyl)ethanol
CAS No.: 174770-74-2
Chemical Name: (R)-2-Amino-2-(4-fluorophenyl)ethanol
Synonyms: (R)-b-AMino-4-fluoro-benzeneethanol;(R)-2-AMino-2-(4-fluorophenyl)ethanol;(2R)-2-amino-2-(4-fluorophenyl)ethanol;Benzeneethanol, β-amino-4-fluoro-, (βR)-;(R)-2-Amino-2-(4-fluorophenyl)ethan-1-ol;(R)-2-AMINO-2-(4-FLUOROPHENYL)ETHANOL HCL;(2R)-2-AMINO-2-(4-FLUOROPHENYL)ETHAN-1-OL;Benzeneethanol, beta-aMino-4-fluoro-, (betaR)-;Benzeneethanol, beta-amino-4-fluoro-, (betaR)- (9CI)
CBNumber: CB11066385
Molecular Formula: C8H10FNO
Formula Weight: 155.17
MOL File: 174770-74-2.mol

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(R)-2-Amino-2-(4-fluorophenyl)ethanol Property

Boiling point:: 287.4±25.0 °C(Predicted)
Density: 1.208±0.06 g/cm3(Predicted)
storage temp.: 2-8°C(protect from light)
pka: 12.48±0.10(Predicted)
Appearance: Off-white to light yellow Solid
optical activity: Consistent with structure
InChI: InChI=1/C8H10FNO/c9-7-3-1-6(2-4-7)8(10)5-11/h1-4,8,11H,5,10H2/t8-/s3
InChIKey: SRQPEYLZIUEVIA-SBYBRXNCNA-N
SMILES: C1([C@@H](N)CO)=CC=C(F)C=C1 |&1:1,r|

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Safety

HS Code: 2922190090

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: A577185
Product name: (R)-2-Amino-2-(4-fluorophenyl)ethanol
Packaging: 50mg
Price: $110
Updated: 2021/12/16

ChemScene

Product number: CS-0037604
Product name: (R)-2-Amino-2-(4-fluorophenyl)ethan-1-ol
Purity: >97.0%
Packaging: 100mg
Price: $70
Updated: 2021/12/16

ChemScene

Product number: CS-0037604
Product name: (R)-2-Amino-2-(4-fluorophenyl)ethan-1-ol
Purity: >97.0%
Packaging: 250mg
Price: $106
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CCH0030491
Product name: (2R)-2-AMINO-2-(4-FLUOROPHENYL)ETHAN-1-OL
Purity: 95.00%
Packaging: 250MG
Price: $351.75
Updated: 2021/12/16

Apolloscientific

Product number: PC911186
Product name: (R)-b-Amino-4-fluoro-benzeneethanol
Purity: 97%
Packaging: 500mg
Price: $360
Updated: 2021/12/16

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(R)-2-Amino-2-(4-fluorophenyl)ethanol Chemical Properties,Usage,Production

Chemical Properties

(R)-2-Amino-2-(4-fluorophenyl)ethanol is a white solid.

Uses

(R)-2-Amino-2-(4-fluorophenyl)ethanol is used for synthesis of organic compounds.

Hazard

H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.

Synthesis

To a stirred solution of lithium aluminium hydride (1.0 M in THF, 11.9 ml, 11.9 mmol) at 0℃ was added 4- (R)-fluorophenylglycine (1.0 g, 5.9 mmol) portion wise over 1 hour. The mixture was stirred at room temperature for 16 hours. Water (0.45 ml), 4 NNaOH (0.45 ml) and water (1.34 ml) was added to the mixture and the mixture was stirred for 10 minutes before being filtered. The filtrate was concentrated to give a yellow residue, (R)-2-Amino-2-(4-fluorophenyl)ethanol.

References

[1] Patent: US5952369, 1999, A
[2] Patent: US5998440, 1999, A
[3] Patent: US5854268, 1998, A

(R)-2-Amino-2-(4-fluorophenyl)ethanol Preparation Products And Raw materials

Raw materials

Preparation Products

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174770-74-2, (R)-2-Amino-2-(4-fluorophenyl)ethanolRelated Search:

Ethanol

Benzeneethanol, beta-amino-4-fluoro-, (betaR)- (9CI)

Benzeneethanol, beta-aMino-4-fluoro-, (betaR)-

(R)-2-AMino-2-(4-fluorophenyl)ethanol

(2R)-2-AMINO-2-(4-FLUOROPHENYL)ETHAN-1-OL

(2R)-2-amino-2-(4-fluorophenyl)ethanol

(R)-2-AMINO-2-(4-FLUOROPHENYL)ETHANOL HCL

(R)-b-AMino-4-fluoro-benzeneethanol

(R)-2-Amino-2-(4-fluorophenyl)ethan-1-ol

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174770-74-2

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