ChemicalBook > CAS DataBase List > 6-Quinazolinecarboxylic acid (9CI)

6-Quinazolinecarboxylic acid (9CI)

Product Name
6-Quinazolinecarboxylic acid (9CI)
CAS No.
676326-53-7
Chemical Name
6-Quinazolinecarboxylic acid (9CI)
Synonyms
quinazoline-6-carboxylic acid;6-Quinazolinecarboxylic acid;Quinazoline-6-carboxylic ...;Quinazoline-6-caeboxylic acid;Quinazoline-7-carboxylic acid;6-Quinazolinecarboxylic acid (9CI)
CBNumber
CB11082358
Molecular Formula
C9H6N2O2
Formula Weight
174.16
MOL File
676326-53-7.mol
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6-Quinazolinecarboxylic acid (9CI) Property

Boiling point:
359.5±17.0 °C(Predicted)
Density 
1.421±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
2.78±0.30(Predicted)
Appearance
Yellow to brown Solid
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Safety

HS Code 
2933992000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

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N-Bromosuccinimide Price

TRC
Product number
Q670130
Product name
Quinazoline-6-carboxylicacid
Packaging
10mg
Price
$45
Updated
2021/12/16
Matrix Scientific
Product number
068539
Product name
6-Quinazolinecarboxylic acid
Purity
>95%
Packaging
1g
Price
$1235
Updated
2021/12/16
AK Scientific
Product number
0413AC
Product name
Quinazoline-6-carboxylicacid
Packaging
100mg
Price
$280
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0393813
Product name
QUINAZOLINE-6-CARBOXYLIC ACID
Purity
95.00%
Packaging
5MG
Price
$500.4
Updated
2021/12/16
Chemenu
Product number
CM108438
Product name
quinazoline-6-carboxylicacid
Purity
98%
Packaging
1g
Price
$636
Updated
2021/12/16
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6-Quinazolinecarboxylic acid (9CI) Chemical Properties,Usage,Production

Uses

Quinazoline-7-carboxylic Acid is a derivative of Quinazoline (Q670100) which is used to study the electrochemical behaviour of quinazoline using modern polarographic and voltammetric methods. Quinazoline is the basic structural unit of pharmaceuticals and plays an important role in modern synthesis of antitumor drugs.

Synthesis

849805-65-8

676326-53-7

Ethyl quinazoline-6-carboxylate (79 mg, 0.391 mmol) was dissolved in ethanol (4 mL), 1 N aqueous sodium hydroxide (4 mL) was added, and the reaction was stirred for 1 h at room temperature. Upon completion of the reaction, the pH of the reaction mixture was adjusted to 4 with 1 N hydrochloric acid, followed by vacuum evaporation to remove the solvent. Ethanol was added to the residue and the organic layer was concentrated. The residue was dissolved in ethyl acetate-tetrahydrofuran mixed solvent and dried with anhydrous magnesium sulfate followed by vacuum evaporation to give quinazoline-6-carboxylic acid (15 mg, 0.086 mmol, 22% yield). The resulting product was directly used in the subsequent reaction without further purification.1H-NMR (DMSO-d6) δ (ppm): 8.09 (1H, d, J = 8.8 Hz), 8.44 (1H, dd, J = 2.0, 8.8 Hz), 8.83 (1H, d, J = 2.0 Hz), 9.39 (1H, s), 9.79 (1H, s).

References

[1] Patent: EP1782811, 2007, A1. Location in patent: Page/Page column 58-59
[2] Patent: EP1669348, 2006, A1. Location in patent: Page/Page column 66-67

6-Quinazolinecarboxylic acid (9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 6-Quinazolinecarboxylic acid (9CI) manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
6-Quinazolinecarboxylic acid (9CI) 676326-53-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-11
Zhuozhou Wenxi import and Export Co., Ltd
Product
6-Quinazolinecarboxylic acid (9CI) 676326-53-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09
Career Henan Chemical Co
Product
6-Quinazolinecarboxylic acid (9CI) 676326-53-7
Price
US $9.80/KG
Min. Order
1g
Purity
≥99%
Supply Ability
100kg
Release date
2020-01-12

676326-53-7, 6-Quinazolinecarboxylic acid (9CI)Related Search:

Formic acid 6-Quinazolinamine (9CI) METHYL QUINOLINE-6-CARBOXYLATE QUINOXALINE-6-CARBALDEHYDE 5-QUINOXALINECARBONITRILE 2-Quinoxalinecarboxylic acid methyl ester QUINOXALINE-5-CARBOXYLIC ACID Methyl quinoxaline-5-carboxylate 6-Quinazolinecarboxaldehyde (9CI) 6-Quinoxalinemethanamine 8-Quinazolinol (6CI,7CI,8CI,9CI) Quinazoline-8-carbonitrile 5-Hydroxyquinoxaline QUINOXALINE-6-CARBOXYLIC ACID HYDRAZIDE Quinoxaline-6-acetic acid 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinoxaline Boronic acid, 6-quinoxalinyl- (9CI) (5-METHOXY-2-OXO-2,3-DIHYDRO-1H-INDOL-3-YL)-ACETIC ACID

  • Quinazoline-6-caeboxylic acid
  • 6-Quinazolinecarboxylic acid (9CI)
  • Quinazoline-7-carboxylic acid
  • Quinazoline-6-carboxylic ...
  • 6-Quinazolinecarboxylic acid
  • quinazoline-6-carboxylic acid
  • 676326-53-7
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