INDEX NAME NOT YET ASSIGNED Property

solubility 

DMSO: slightly soluble; Methanol: slightly soluble

form 

A solid

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H317May cause an allergic skin reaction

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P321Specific treatment (see … on this label).

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

INDEX NAME NOT YET ASSIGNED Chemical Properties,Usage,Production

Description

Sulfamethizole-d₄ is intended for use as an internal standard for the quantification of sulfamethizole by GC- or LC-MS. Sulfamethizole is a broad-spectrum sulfonamide antibiotic (MIC₉₀s = 1.25-5,000 μg/ml against clinical isolates of E. coli and K. pneumoniae).¹ It inhibits dihydropteroate synthase, an enzyme involved in folate biosynthesis. Formulations containing sulfamethizole have previously been used to treat urinary tract infections.

References

1. Wambaugh, M.A., Shakya, V.P.S., Lewis, A.J., et al. High-throughput identification and rational design of synergistic small-molecule pairs for combating and bypassing antibiotic resistance PLoS Biol. 15(6):e2001644,(2017).