ChemicalBook > CAS DataBase List > 3-CHLORO-2,4-DIFLUOROBENZONITRILE

3-CHLORO-2,4-DIFLUOROBENZONITRILE

Product Name
3-CHLORO-2,4-DIFLUOROBENZONITRILE
CAS No.
887267-38-1
Chemical Name
3-CHLORO-2,4-DIFLUOROBENZONITRILE
Synonyms
3-Chloro-2,4-difluorobenzonitrile;Benzonitrile, 3-chloro-2,4-difluoro-
CBNumber
CB11090685
Molecular Formula
C7H2ClF2N
Formula Weight
173.55
MOL File
887267-38-1.mol
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3-CHLORO-2,4-DIFLUOROBENZONITRILE Property

Boiling point:
208.8±35.0 °C(Predicted)
Density 
1.43±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
Appearance
White to off-white Solid
CAS DataBase Reference
887267-38-1
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Safety

HS Code 
2926907090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Synthonix
Product number
C43996
Product name
3-Chloro-2,4-difluorobenzonitrile
Purity
98%
Packaging
250mg
Price
$53
Updated
2026/05/06
Synthonix
Product number
C43996
Product name
3-Chloro-2,4-difluorobenzonitrile
Purity
98%
Packaging
1g
Price
$60
Updated
2026/05/06
Synthonix
Product number
C43996
Product name
3-Chloro-2,4-difluorobenzonitrile
Purity
98%
Packaging
5g
Price
$180
Updated
2026/05/06
Synthonix
Product number
C43996
Product name
3-Chloro-2,4-difluorobenzonitrile
Purity
98%
Packaging
10g
Price
$650
Updated
2026/05/06
Synthonix
Product number
C43996
Product name
3-Chloro-2,4-difluorobenzonitrile
Purity
98%
Packaging
25g
Price
$1460
Updated
2026/05/06
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3-CHLORO-2,4-DIFLUOROBENZONITRILE Chemical Properties,Usage,Production

Synthesis

2112-31-4

887267-38-1

Using the compound (CAS:2112-31-4) as starting material, 29.0 g of potassium fluoride (KF) was slowly added to the solution prepared in step (3) under continuous stirring conditions. Subsequently, the reaction mixture was heated to 140-160 °C and maintained at this temperature until the content of 2,3,4-trichlorobenzonitrile was reduced to less than 2% as detected by conventional analytical methods (Step 5). After completion of the reaction, the solvent N,N-dimethylformamide (DMF) was removed by rotary evaporator under reduced pressure to give a brownish-yellow granular solid. The solid was dissolved in 200 mL of toluene and purified by recrystallization. The solution was cooled to about 0 °C and allowed to stand overnight, after which the crystals were collected by filtration and dried to give 33.8 g of 3-chloro-2,4-difluorobenzonitrile. The product was a light yellow granular solid, analyzed by gas chromatography (GC) with a purity of 98.637% and a molar yield of 65.0%.

References

[1] Patent: CN106278860, 2017, A. Location in patent: Paragraph 0023; 0028; 0029

3-CHLORO-2,4-DIFLUOROBENZONITRILE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-CHLORO-2,4-DIFLUOROBENZONITRILE Suppliers

changzhou ansciep chemical co., ltd.
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0519-86305871
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tina@ansciepchem.com
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China
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3B Pharmachem (Wuhan) International Co.,Ltd.
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3bsc@sina.com
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Alfa Aesar
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400-6106006
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021-67582001/03/05
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Shanghai Harvest Chemical Industrial Co., Ltd.
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Hangzhou Yuhao Chemical Technology Co., Ltd
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Tianjin Jinyuda Chemical Co., Ltd.
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Shanghai Aladdin Bio-Chem Technology Co.,LTD
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021-50323701
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Shanghai Yolne Chemical Co., Ltd.
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021-52212593
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View Lastest Price from 3-CHLORO-2,4-DIFLUOROBENZONITRILE manufacturers

Career Henan Chemical Co
Product
3-CHLORO-2,4-DIFLUOROBENZONITRILE 887267-38-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2020-01-08

887267-38-1, 3-CHLORO-2,4-DIFLUOROBENZONITRILERelated Search:


  • 3-Chloro-2,4-difluorobenzonitrile
  • Benzonitrile, 3-chloro-2,4-difluoro-
  • 887267-38-1