Flesinoxan

Product Name: Flesinoxan
CAS No.: 98205-89-1
Chemical Name: Flesinoxan
Synonyms: Flesinoxan HCl;4-fluoro-N-[2-[4-[(2S)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-5-yl]piperazin-1-yl]ethyl]benzamide;Benzamide, N-(2-(4-(2,3-dihydro-2-(hydroxymethyl)-1,4-benzodioxin-5-yl)-1-piperazinyl)ethyl)-4-fluoro-, monohydrochloride;Benzamide, N-(2-(4-((2R)-2,3-dihydro-2-(hydroxymethyl)-1,4-benzodioxin-5-yl)-1-piperazinyl)ethyl)-4-fluoro-, monohydrochloride
CBNumber: CB11116925
Molecular Formula: C22H26FN3O4
Formula Weight: 451.9188832
MOL File: 98205-89-1.mol

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Flesinoxan Property

Melting point:: 184.5-185.5°; mp 183.0-184.0° (Ennis)
alpha: D +25° (c = 1 in methanol)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0002711
Product name: FLESINOXAN HYDROCHLORIDE
Purity: 95.00%
Packaging: 5MG
Price: $501.2
Updated: 2021/12/16

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Flesinoxan Chemical Properties,Usage,Production

Uses

Flesinoxan hydrochloride is a hypotensive agent and a potent, high affinity and selective 5-hydroxytryptamine1A (5-HT1A) receptor agonist with an EC50 value of 24 nM. Flesinoxan hydrochloride also has effective anxiolytic/antidepressant effects[1][2][3].

References

[1] Hadrava V, et al. Characterization of 5-hydroxytryptamine1A properties of flesinoxan: in vivo electrophysiology and hypothermia study. Neuropharmacology. 1995 Oct;34(10):1311-26. DOI:10.1016/0028-3908(95)00098-q
[2] Schoeffter P, et al. Centrally acting hypotensive agents with affinity for 5-HT1A binding sites inhibit forskolin-stimulated adenylate cyclase activity in calf hippocampus. Br J Pharmacol. 1988 Nov;95(3):975-85. DOI:10.1111/j.1476-5381.1988.tb11728.x
[3] Rodgers RJ, et al. Antianxiety and behavioral suppressant actions of the novel 5-HT1A receptor agonist, flesinoxan. Pharmacol Biochem Behav. 1994 Aug;48(4):959-63. DOI:10.1016/0091-3057(94)90205-4

Flesinoxan Preparation Products And Raw materials

Raw materials

Preparation Products

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Flesinoxan Suppliers

China 1 United Kingdom 1 United States 3 Global 5

TargetMol Chemicals Inc.

Tel: 15002134094
Email: marketing@targetmol.cn
Country: China
ProdList: 29423
Advantage: 58

TargetMol Chemicals Inc.

Tel: +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 19962
Advantage: 58

98205-89-1, FlesinoxanRelated Search:

1,2-Propanediol, 3-(o-(dimethylamino)phenoxy)- 5-Amino-1,4-benzodioxane Flesinoxan 1-(2-ETHOXYPHENYL)PIPERAZINE HYDROCHLORIDE 1-(3-Ethoxyphenyl)-piperazine dihydrochloride 1-(2,3-DIHYDRO-1,4-BENZODIOXIN-5-YL)-PIPERAZINE HYDROCHLORIDE

Benzamide, N-(2-(4-((2R)-2,3-dihydro-2-(hydroxymethyl)-1,4-benzodioxin-5-yl)-1-piperazinyl)ethyl)-4-fluoro-, monohydrochloride

Benzamide, N-(2-(4-(2,3-dihydro-2-(hydroxymethyl)-1,4-benzodioxin-5-yl)-1-piperazinyl)ethyl)-4-fluoro-, monohydrochloride

Flesinoxan HCl

4-fluoro-N-[2-[4-[(2S)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-5-yl]piperazin-1-yl]ethyl]benzamide

98205-89-1