Rutamycin

Product Name: Rutamycin
CAS No.: 1404-59-7
Chemical Name: Rutamycin
Synonyms: A-272;RR-32705;Rutamycin;RRNo-32705;oligomycin D;26-Demethyloligomycin A;RutaMycin, 26-deMethyloligoMycin A, A 272, RR 32705, RutaMycin A;Spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-[2H]pyran]-3,9,13-trione,22-ethyl-3',4',5',6'-tetrahydro-7,11,14,15-tetrahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,29-octamethyl-,(1S,2'R,4E,5'S,6S,6'S,7S,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,29R)-;Spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-[2H]pyran]-3,9,13-trione, 22-ethyl-3',4',5',6'-tetrahydro-7,11,14,15-tetrahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,29-octamethyl-, (1S,2'R,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,29R)-
CBNumber: CB11120704
Molecular Formula: C44H72O11
Formula Weight: 777.042
MOL File: 1404-59-7.mol

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Rutamycin Property

Melting point:: 116-119°
alpha: D20 -62° (c = 1.36 in CHCl3)
Boiling point:: 883.4±65.0 °C(Predicted)
Density: 1.15±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
form: A lyophilisate
pka: 12.52±0.70(Predicted)

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Safety

RIDADR: 2811
HazardClass: 6.1(b)
PackingGroup: III
Toxicity: LD50 oral in mouse: 800mg/kg

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 20184
Product name: Oligomycin D
Purity: ≥95%
Packaging: 500μg
Price: $335
Updated: 2024/03/01

Cayman Chemical

Product number: 20184
Product name: Oligomycin D
Purity: ≥95%
Packaging: 2.5mg
Price: $751
Updated: 2024/03/01

American Custom Chemicals Corporation

Product number: API0012448
Product name: RUTAMYCIN
Purity: 95.00%
Packaging: 5MG
Price: $501.12
Updated: 2021/12/16

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Rutamycin Chemical Properties,Usage,Production

Description

Oligomycin D is a macrolide antibiotic produced by several species of Streptomyces that inhibits the mitochondrial F₁F_O-ATPase and is used to uncouple oxidative phosphorylation from electron transport. Oligomycin D is reported to inhibit K-Ras plasma membrane localization in MDCK cells with an IC₅₀ value of 3.49 nM and is cytotoxic to SW620 colon cancer cells with an IC₅₀ value of 36 μM.

Uses

Oligomycin D (rutamycin) is macrocyclic lactone belonging to the oligomycin class but identified from different species of Streptomyces in 1961. Like oligomycin A, oligomycin D inhibits mitochondrial F1F0-ATPase and is an important bioprobe to study the organisation of ATPase on the mitochondrial membrane. Oligomycin D exhibits a broad biological profile including antifungal, antitumor and nematocidal activities.

Uses

Oligomycin D is an inhibitor of mitochondrial F1F0-ATPase.

Rutamycin Preparation Products And Raw materials

Raw materials

Preparation Products

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Rutamycin Suppliers

CHINA 29 South Korea 1 United Kingdom 1 United States 4 Global 35

Lynnchem

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1404-59-7, RutamycinRelated Search:

Chloramphenicol Natamycin OLIGOMYCIN Rutamycin

oligomycin D

26-Demethyloligomycin A

A-272

RR-32705

RRNo-32705

RutaMycin, 26-deMethyloligoMycin A, A 272, RR 32705, RutaMycin A

Rutamycin

Spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-[2H]pyran]-3,9,13-trione,22-ethyl-3',4',5',6'-tetrahydro-7,11,14,15-tetrahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,29-octamethyl-,(1S,2'R,4E,5'S,6S,6'S,7S,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,29R)-

Spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-[2H]pyran]-3,9,13-trione, 22-ethyl-3',4',5',6'-tetrahydro-7,11,14,15-tetrahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,29-octamethyl-, (1S,2'R,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,29R)-

1404-59-7

C44H72O11