CIS-3-IODOACRYLIC ACID ETHYL ESTER Property

Boiling point:

85 °C/20 mmHg (lit.)

Density 

1.765 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.533(lit.)

Flash point:

210 °F

storage temp. 

2-8°C

solubility 

Chloroform, Ethyl Acetate (Slightly)

form 

Oil

color 

Clear Colourless

CAS DataBase Reference

31930-36-6

Safety

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26

WGK Germany 

3

HS Code 

29161900

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

CIS-3-IODOACRYLIC ACID ETHYL ESTER Chemical Properties,Usage,Production

Uses

Ethyl Cis-?3-?iodoacrylate is a reactant used in the synthesis of complex naphtho(benzo)furans as well as in the cobalt-catayzed cross coupling of functionalized organozinc pivalates.

Uses

Ethyl cis-3-iodoacrylate may be used in the synthesis of the following:

• vinyl sulfides
• (Z)-1-iodohept-1-en-3-ol
• (E)-1-iodohept-1-en-3-ol
• (Z)-β-iodoacrolein
• 6-oxo-M₁Guo

General Description

Ethyl cis-3-iodoacrylate (cis-ethyl-β-iodoacrylate, ethyl (Z)-β-iodoacrylate) is Z-vinyl iodide derivative. It is reported to be prepared from ethyl propiolate by treating with sodium iodide. Its Suzuki coupling reaction with cyclic vinyl boronic acids has been studied.