3-PYRIDINAMINE, 6-(1-METHYLETHYL)-
- Product Name
- 3-PYRIDINAMINE, 6-(1-METHYLETHYL)-
- CAS No.
- 405103-02-8
- Chemical Name
- 3-PYRIDINAMINE, 6-(1-METHYLETHYL)-
- Synonyms
- 6-Isopropylpyridin-3-amine;6-lsopropylpyridin-3-aMine;6-Isopropyl-3-pyridinamine;5-AMino-2-isopropylpyridine;3-Amino-6-isopropylpyridine;6-Isopropyl-pyridin-3-ylamine;6-(propan-2-yl)pyridin-3-aMine;5-Amino-2-isopropylpyridine 95%;6-(1-Methylethyl)-3-Pyridinamine;3-PYRIDINAMINE, 6-(1-METHYLETHYL)-
- CBNumber
- CB1114395
- Molecular Formula
- C8H12N2
- Formula Weight
- 136.19
- MOL File
- 405103-02-8.mol
3-PYRIDINAMINE, 6-(1-METHYLETHYL)- Property
- Boiling point:
- 255.1±20.0 °C(Predicted)
- Density
- 1.008±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 6.77±0.10(Predicted)
- Appearance
- Light yellow to brown Liquid
- InChI
- InChI=1S/C8H12N2/c1-6(2)8-4-3-7(9)5-10-8/h3-6H,9H2,1-2H3
- InChIKey
- XYGFISRAXLLACA-UHFFFAOYSA-N
- SMILES
- C1=NC(C(C)C)=CC=C1N
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- I872965
- Product name
- 6-Isopropylpyridin-3-amine
- Packaging
- 250mg
- Price
- $185
- Updated
- 2021/12/16
- Product number
- FA10609
- Product name
- 3-Amino-6-isopropylpyridine
- Packaging
- 50mg
- Price
- $70
- Updated
- 2021/12/16
- Product number
- FA10609
- Product name
- 3-Amino-6-isopropylpyridine
- Packaging
- 100mg
- Price
- $100
- Updated
- 2021/12/16
- Product number
- FA10609
- Product name
- 3-Amino-6-isopropylpyridine
- Packaging
- 250mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- Z4708
- Product name
- 6-Isopropylpyridin-3-amine
- Packaging
- 1g
- Price
- $232
- Updated
- 2021/12/16
3-PYRIDINAMINE, 6-(1-METHYLETHYL)- Chemical Properties,Usage,Production
Uses
6-Isopropylpyridin-3-amine is used to prepare quinolinonecarboxamides as modulators of ATP-binding cassette transporters.
Synthesis
131941-21-4
405103-02-8
General procedure for the synthesis of 3-amino-6-isopropylpyridine from 2-isopropyl-5-nitropyridine: 2-isopropyl-5-nitropyridine (1.30 g, 7.82 mmol) was dissolved in methanol (20 mL) and Raney Ni catalyst (0.25 g) was added. The reaction mixture was stirred for 2 hours at room temperature under hydrogen (1 atm) atmosphere. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated under reduced pressure to afford 2-isopropyl-5-aminopyridine (E-9) (0.55 g, 52% yield). The product was characterized by 1H NMR (CDCl3): δ 8.05 (s, 1H), 6.93-6.99 (m, 2H), 3.47 (br s, 2H), 2.92-3.02 (m, 1H), 1.24-1.26 (m, 6H).ESI-MS showed the molecular ion peak at 137.2 m/z (MH+).
References
[1] Patent: US2011/98311, 2011, A1
[2] Patent: US2012/309758, 2012, A1
[3] Patent: US2015/231142, 2015, A1. Location in patent: Paragraph 0700
3-PYRIDINAMINE, 6-(1-METHYLETHYL)- Preparation Products And Raw materials
Raw materials
Preparation Products
3-PYRIDINAMINE, 6-(1-METHYLETHYL)- Suppliers
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- info@chemstep.com
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- Europe
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View Lastest Price from 3-PYRIDINAMINE, 6-(1-METHYLETHYL)- manufacturers
- Product
- 6-Isopropylpyridin-3-amine 405103-02-8
- Price
- US $0.00/KG
- Min. Order
- 0.0001KG
- Purity
- 98%min
- Supply Ability
- 500kgs/month
- Release date
- 2022-05-11
- Product
- 3-PYRIDINAMINE, 6-(1-METHYLETHYL)- 405103-02-8
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-10-27
- Product
- 3-PYRIDINAMINE, 6-(1-METHYLETHYL)- 405103-02-8
- Price
- US $280.00/G
- Min. Order
- 1G
- Purity
- 99%
- Supply Ability
- customise
- Release date
- 2018-08-01