ChemicalBook > CAS DataBase List > (R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE

(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE

Product Name
(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE
CAS No.
443347-10-2
Chemical Name
(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE
Synonyms
(S)-Xyl-P-Phos;(S)-XYLYL-P-PHOS;(R)-XYLYL-P-PHOS;CTH-(S)-XYLYL-P-PHOS;CTH-(R)-XYLYL-P-PHOS;min.cth-(s)-xylyl-p-phos;(S)-(-)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS&;(S)-(-)-2,2'',6,6''-Tetramethoxy-4,4''-bis(di(3,5-xylyl)phosphi;(S)-(-)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE;(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE
CBNumber
CB1116203
Molecular Formula
C46H50N2O4P2
Formula Weight
756.85
MOL File
443347-10-2.mol
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(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE Property

Melting point:
158-162°C
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
Powder
color 
white to pale yellow
Water Solubility 
Sparingly soluble in water.
CAS DataBase Reference
443347-10-2
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37/39-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
675946
Product name
(S)-(?)-2,2′,6,6′-Tetramethoxy-4,4′-bis[di(3,5-xylyl)phosphino]-3,3′-bipyridine
Purity
97%
Packaging
100mg
Price
$89.2
Updated
2023/06/20
Sigma-Aldrich
Product number
675946
Product name
(S)-(?)-2,2′,6,6′-Tetramethoxy-4,4′-bis[di(3,5-xylyl)phosphino]-3,3′-bipyridine
Purity
97%
Packaging
500mg
Price
$261
Updated
2023/06/20
Alfa Aesar
Product number
044614
Product name
(S)-(-)-2,2',6,6'-Tetramethoxy-4,4'-bis(di(3,5-xylyl)phosphino)-3,3'-bipyridine
Packaging
0.1g
Price
$73.65
Updated
2024/03/01
Alfa Aesar
Product number
044614
Product name
(S)-(-)-2,2',6,6'-Tetramethoxy-4,4'-bis(di(3,5-xylyl)phosphino)-3,3'-bipyridine
Packaging
0.5g
Price
$311.65
Updated
2024/03/01
Strem Chemicals
Product number
15-5211
Product name
(S)-(-)-2,2',6,6'-Tetramethoxy-4,4'-bis(di(3,5-xylyl)phosphino)-3,3'-bipyridine, min. 95% CTH-(S)-Xylyl-P-Phos
Packaging
100mg
Price
$74
Updated
2024/03/01
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(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE Chemical Properties,Usage,Production

Chemical Properties

White solid

Uses

(S)-(-)-2,2',6,6'-Tetramethoxy-4,4'-bis(di(3,5-xylyl)phosphino)-3,3'-bipyridine is used in Pharmaceutical and industry applications.

Uses

Ligand employed in the asymmetic hydrogenation of ?-keto esters, 2-arylacrylates, aryl ketones , and other substrates.

Reactions

  1. Chiral ligand for the asymmetric hydrogenation of β-keto esters.
  2. Chiral ligand for enantioselective rhodium-catalyzed [2+2+2] carbocyclization reactions.
  3. Chiral ligand for ruthenium catalyzed hydrogenation of (E)-β-(acylamino)acrylates to β-amino acids.
  4. The Rhodium complex gives higher enantioselectivity for hydrogenation of (Z)-β-(acylamino)acrylates to β-amino acids.
  5. Chiral ligand for copper-catalyzed asymmetric hydrosilylation of ketones.
  6. Chiral ligand for asymmetric allylic substitution reactions using boronic acids as nucleophiles.
  7. Gives useful selectivity in asymmetric Pauson-Khand-type cyclizations.

(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE Suppliers

China 27 Europe 2 Germany 2 India 2 Norway 1 Switzerland 1 United Kingdom 1 United States 5 Global 41
Chiron AS
Tel
--
Fax
--
Email
chiron@chiron.no
Country
Norway
ProdList
2801
Advantage
72

443347-10-2, (R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINERelated Search:

(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE

  • (S)-(-)-2,2',6,6'-Tetramethoxy-4,4'-bis(di(3,5-xylyl)phosphino)-3,3'-bipyridine,min.95%CTH-(S)-Xylyl-P-Phos
  • (r)-(+)-2,2',6,6'-tetramethoxy-4,4'-bis(di(3,5-xylyl)phosphino)-3,3'-bipyridine *cth-(r)-xylyl-p-phos*
  • (s)-(-)-2,2',6,6'-tetramethoxy-4,4'-bis(di(3,5-xylyl)phosphino)-3,3'-bipyridine *cth-(s)-xylyl-p-phos*
  • (R)-(+)-2,2'',6,6''-TETRAMETHOXY-4,4''-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3''-BIPYRIDINE *CTH-(R)-XYLYL-P-PHO
  • (S)-(-)-2,2',6,6'-Tetramethoxy-4,4'-bis(di(3,5-xylyl)phosphino)-3,3'-bipyridine, CTH-(S)-Xylyl-P-Phos, 95% Application:Asymmetric hydrogenation Store N2Ar
  • (S)-(-)-2,2',6,6'-Tetramethoxy-4,4'-bis(di(3,5-xylyl)phosphino)-3,3'-bipyridine *CTH-(S)-Xylyl-P-Pho
  • (3S)-4,4'-Bis[bis(3,5-dimethylphenyl)phosphino]-2,2',6,6'-tetramethoxy-3,3'-bipyridine
  • (S)-Xyl-P-Phos
  • (S)-(-)-2,2',6,6'-Tetramethoxy-4,4'-bis[di(3,5-xylyl)phosphino]-3,3'-bipyridine 97%
  • CTH-(R)-XYLYL-P-PHOS
  • CTH-(S)-XYLYL-P-PHOS
  • (S)-XYLYL-P-PHOS
  • (S)-(-)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE
  • (R)-XYLYL-P-PHOS
  • (R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE
  • (S)-(-)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS&
  • min.cth-(s)-xylyl-p-phos
  • (S)-4,4'-Bis(bis(3,5-dimethylphenyl)phosphino)-2,2',6,6'-tetramethoxy-3,3'-bipyridine
  • 3,3'-Bipyridine, 4,4'-bis[bis(3,5-dimethylphenyl)phosphino]-2,2',6,6'-tetramethoxy-, (3S)-
  • (S)-4,4'-Bis(bis(3,5-dimethylphenyl)phosphino)-2,2',6,6'-tetramethoxy-3,3'-bipyridine[(S)-Xylyl-P-Phos
  • (S)-(-)-2,2'',6,6''-Tetramethoxy-4,4''-bis(di(3,5-xylyl)phosphi
  • (S)-4,4'-Bis(bis(3,5-dimethylphenyl)phosphino)-2,2',6,6'-tetramethoxy-3,3'-bipyridine
  • (R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE
  • 443347-10-2
  • C46H50N2O4P2
  • Hydrogenation
  • Asymmetric Synthesis
  • Chiral Catalysts, Ligands, and Reagents