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4-Hydroxy Valsartan, Mixture of Diastereomers

Product Name
4-Hydroxy Valsartan, Mixture of Diastereomers
CAS No.
188259-69-0
Chemical Name
4-Hydroxy Valsartan, Mixture of Diastereomers
Synonyms
CGP 71580;Valsartan 4-Hydroxy;Valsartan Impurity I;Valsartan related compound I;Valsartan 4-Hydroxy Impurity;(2S)-2-(N-((2'-(1H-tetrazol-5-yl);Valsartan 4-Hydroxy Valeryl Analog;4-Hydroxy Valsartan, Mixture of Diastereomers;N-(4-Hydroxy-1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl) [1,1'-biphenyl]-4-yl]Methyl]-;N-(4-Hydroxy-1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine
CBNumber
CB11175870
Molecular Formula
C24H29N5O4
Formula Weight
451.52
MOL File
188259-69-0.mol
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4-Hydroxy Valsartan, Mixture of Diastereomers Property

Melting point:
130-132°C
storage temp. 
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility 
Methanol (Slightly)
form 
Solid
color 
White to Off-White
Stability:
Hygroscopic
CAS DataBase Reference
188259-69-0
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
27849
Product name
4-hydroxy Valsartan
Packaging
2.5mg
Price
$396
Updated
2024/03/01
TRC
Product number
H995000
Product name
4-HydroxyValsartan(MixtureofDiastereomers)
Packaging
25mg
Price
$1390
Updated
2021/12/16
TRC
Product number
H995000
Product name
4-HydroxyValsartan(MixtureofDiastereomers)
Packaging
2.5mg
Price
$180
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0000265
Product name
4-HYDROXY VALSARTAN
Purity
95.00%
Packaging
25MG
Price
$2243.59
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0000265
Product name
4-HYDROXY VALSARTAN
Purity
95.00%
Packaging
2.5MG
Price
$952.88
Updated
2021/12/16
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4-Hydroxy Valsartan, Mixture of Diastereomers Chemical Properties,Usage,Production

Description

4-hydroxy Valsartan is a major metabolite of the angiotensin II type 1 (AT1) receptor antagonist valsartan . It reduces platelet aggregation induced by epinephrine and collagen but not ADP in human whole blood.

Chemical Properties

White Solid

Uses

A nonpeptide angiotensin II AT1-receptor antagonist.

Definition

ChEBI: 4-Hydroxyvalsartan is a valine derivative.

References

[1] VICTOR L SEREBRUANY. Effects of valsartan and valeryl 4-hydroxy valsartan on human platelets: a possible additional mechanism for clinical benefits.[J]. Journal of Cardiovascular Pharmacology, 2004, 43 5: 677-684. DOI: 10.1097/00005344-200405000-00010

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View Lastest Price from 4-Hydroxy Valsartan, Mixture of Diastereomers manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
4-Hydroxy Valsartan, Mixture of Diastereomers 188259-69-0
Price
US $0.10/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
1000 tons
Release date
2020-04-27
Shaanxi Dideu Medichem Co. Ltd
Product
4-Hydroxy Valsartan 188259-69-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99.0%+
Supply Ability
60 tons
Release date
2019-12-30
Shaanxi Dideu Medichem Co. Ltd
Product
4-Hydroxy Valsartan (Mixture of DiastereoMers) 188259-69-0
Price
US $0.00-0.00/Kg
Min. Order
1KG
Purity
99.0%+
Supply Ability
100 tons
Release date
2020-01-15

188259-69-0, 4-Hydroxy Valsartan, Mixture of DiastereomersRelated Search:


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