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Bis(2-mercaptoethyl) sulfone

Product Name
Bis(2-mercaptoethyl) sulfone
CAS No.
145626-87-5
Chemical Name
Bis(2-mercaptoethyl) sulfone
Synonyms
Bis(2-thioethyl) sulphone;2,2'-Sulfonylbis-ethanethiol;Ethanethiol, 2,2'-sulfonylbis-;Bis(2-mercaptoethyl) sulphone, 2,2'-Sulphonyldiethanethiol
CBNumber
CB11176170
Molecular Formula
C4H10O2S3
Formula Weight
186.32
MOL File
145626-87-5.mol
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Bis(2-mercaptoethyl) sulfone Property

Melting point:
57-58°C
Boiling point:
375.6±27.0 °C(Predicted)
Density 
1.296±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer, Under Inert Atmosphere
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
solid
pka
pKa (aqueous soln at 25°): 7.9, 9.0
color 
Pale yellow
Stability:
Moisture Sensitive
CAS DataBase Reference
145626-87-5
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Safety

HS Code 
2930909899
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC
Product number
B482500
Product name
Bis(2-mercaptoethyl)sulfone
Packaging
1g
Price
$310
Updated
2021/12/16
AK Scientific
Product number
1514CH
Product name
Bis(2-mercaptoethyl)sulfone
Packaging
500mg
Price
$441
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB18676
Product name
Bis(2-mercaptoethyl)sulfone
Packaging
1g
Price
$460
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
7507
Product name
Bis(2-mercaptoethyl)sulfone
Packaging
1g
Price
$830
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
7507
Product name
Bis(2-mercaptoethyl)sulfone
Packaging
5G
Price
$1640
Updated
2021/12/16
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Bis(2-mercaptoethyl) sulfone Chemical Properties,Usage,Production

Chemical Properties

White Crystalline Solid

Uses

Bis(2-mercaptoethyl) sulfone is a useful reagent for the reduction of disulfides in aquous solutions. It is a superior substitute for DTT.

Uses

Reagent for reduction of disulfide bonds in aqueous solutions.

Purification Methods

BMS recrystallises from hexane as white fluffy crystals. Large amounts are best recrystallised from de-oxygenated H2O (charcoal). It is a good alternative reducing agent to dithiothreitol. Its IR (film) has 2995, 2657, 1306, 1248, 1124 and 729 cm-1 . The synthetic intermediate thioacetate has m 82-83o (white crystals from CCl4). The disulfide is purified by flash chromatography on SiO2 and elution with 50% EtOAc/hexane and recrystallised from hexane, and has m 137-139o. [Lamoureux & Whitesides J Org Chem 58 633 1993, Beilstein 1 IV 2455.]

Bis(2-mercaptoethyl) sulfone Preparation Products And Raw materials

Raw materials

Preparation Products

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Bis(2-mercaptoethyl) sulfone Suppliers

Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
Apollo Scientific Ltd.
Tel
--
Fax
--
Email
sales@apolloscientific.co.uk
Country
United Kingdom
ProdList
6084
Advantage
88

145626-87-5, Bis(2-mercaptoethyl) sulfoneRelated Search:


  • Bis(2-thioethyl) sulphone
  • Bis(2-mercaptoethyl) sulphone, 2,2'-Sulphonyldiethanethiol
  • 2,2'-Sulfonylbis-ethanethiol
  • Ethanethiol, 2,2'-sulfonylbis-
  • 145626-87-5
  • Metal Isotopes
  • Sulfur & Selenium Compounds