Fenofibrate-d6
- Product Name
- Fenofibrate-d6
- CAS No.
- 1092484-56-4
- Chemical Name
- Fenofibrate-d6
- Synonyms
- Lipsin-d6; LF 178-d6;Lipirex-d6;Liposit-d6;Nolipax-d6;Lipofene-d6;Lipoclar-d6;Lipantil-d6;MeltDose-d6;Lipanthyl-d6
- CBNumber
- CB11176332
- Molecular Formula
- C20H21ClO4
- Formula Weight
- 360.83
- MOL File
- 1092484-56-4.mol
Fenofibrate-d6 Property
- Melting point:
- 70-720C
- storage temp.
- -20°C Freezer
- solubility
- Chloroform (Slightly), Methanol (Sightly)
- form
- Solid
- color
- White to Off-White
- CAS DataBase Reference
- 1092484-56-4
N-Bromosuccinimide Price
- Product number
- 25710
- Product name
- Fenofibrate-d6
- Purity
- ≥99% deuterated forms (d1-d6)
- Packaging
- 500μg
- Price
- $93
- Updated
- 2024/03/01
- Product number
- 25710
- Product name
- Fenofibrate-d6
- Purity
- ≥99% deuterated forms (d1-d6)
- Packaging
- 1mg
- Price
- $166
- Updated
- 2024/03/01
- Product number
- 25710
- Product name
- Fenofibrate-d6
- Purity
- ≥99% deuterated forms (d1-d6)
- Packaging
- 5mg
- Price
- $684
- Updated
- 2024/03/01
- Product number
- F248642
- Product name
- Fenofibrate-d6
- Packaging
- 1mg
- Price
- $175
- Updated
- 2021/12/16
- Product number
- 011976
- Product name
- Fenofibrate-d6
- Packaging
- 1mg
- Price
- $446
- Updated
- 2021/12/16
Fenofibrate-d6 Chemical Properties,Usage,Production
Description
Fenofibrate-d6 is intended for use as an internal standard for the quantification of fenofibrate by GC- or LC-MS. Fenofibrate is an agonist of peroxisome proliferator-activated receptor α (PPARα) with EC50 values of 18 and 30 μM for mouse and human receptors, respectively, in a transactivation assay. It is selective for PPARα over PPARγ (EC50s = 300 and 200 μM for mouse and human receptors, respectively) and lacks activity at mouse and human PPARδ at a concentration of 100 μM. In vivo, fenofibrate (50-100 mg/kg) reduces plasma levels of triglycerides, C-reactive protein, and malondialdehyde (MDA) in mice with fructose-induced hypertriglycemia in a dose-dependent manner. It decreases glomerular and tubular atrophy and necrosis induced by cisplatin in rat kidney when administered at a dose of 100 mg/kg. Fenofibrate also reduces the number of pulmonary lesions induced by 4-nitroquinoline 1-oxide (4-NQO) in lung of Tsumura Suzuki obese diabetic (TSOD) mice.
Chemical Properties
White Solid
Uses
Antilipemic. It is a lipid regulating drug. Increases high density lipoprotein levels by reducing cholesteryl ester transfer protein expresion.
Fenofibrate-d6 Preparation Products And Raw materials
Raw materials
Preparation Products
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