ChemicalBook > CAS DataBase List > Amixetrine

Amixetrine

Product Name
Amixetrine
CAS No.
24622-72-8
Chemical Name
Amixetrine
Synonyms
Amixetrine;1-[2-(3-Methylbutoxy)-2-phenylethyl]pyrrolidine;Pyrrolidine, 1-[2-(3-methylbutoxy)-2-phenylethyl]-
CBNumber
CB11178013
Molecular Formula
C17H27NO
Formula Weight
261.4
MOL File
24622-72-8.mol
More
Less

Amixetrine Property

Boiling point:
bp2 121°
Density 
0.9379 (rough estimate)
refractive index 
nD21.6 1.4978
pka
9.57±0.20(Predicted)
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0010697
Product name
AMIXETRINE
Purity
95.00%
Packaging
5MG
Price
$495.22
Updated
2021/12/16
More
Less

Amixetrine Chemical Properties,Usage,Production

Originator

Somagest,Riom,France,1972

Definition

ChEBI: Amixetrine is a benzyl ether.

Manufacturing Process

There is heated under reflux with stirring for 10 hours: 117 g of (2-phenyl-2-isoamyloxy)ethyl bromide, 61.5g of pyrrolidine and 250 ml of toluene.
After filtration of the pyrrolidine hydrobromide, the toluene is removed under reduced pressure. The residue is then taken up with 4 N HCl. The aqueous solution is washed with ether. It is made alkaline by a solution of 50% NaOH. It is extracted with ether. The ethereal phase is dried over anhydrous sodium sulfate, and rectified under reduced pressure after removing the solvent. There is thus obtained 90 g of a colorless oil with an amine odor.
The hydrochloride is prepared in the usual manner by dissolving the amine in anhydrous ether and adding to it the requisite amount of dry gaseous hydrochloric acid, dissolved in absolute alcohol. There is obtained a white crystalline powder melting at 150°C, very soluble in water and alcohol, very slightly soluble in ether and ethyl acetate.
The starting material above is prepared by reacting styrene with isoamyl alcohol and then reacting that product with t-butyl hypobromite.

Therapeutic Function

Antiinflammatory, Anticholinergic, Antidepressant

Amixetrine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Amixetrine Suppliers

Lanospharma Laboratories Co.,Ltd
Tel
--
Fax
--
Email
sales@lanospharma.com
Country
China
ProdList
6329
Advantage
56

24622-72-8, AmixetrineRelated Search:


  • Amixetrine
  • 1-[2-(3-Methylbutoxy)-2-phenylethyl]pyrrolidine
  • Pyrrolidine, 1-[2-(3-methylbutoxy)-2-phenylethyl]-
  • 24622-72-8