ChemicalBook > CAS DataBase List > Meclonazepam
Meclonazepam
- Product Name
- Meclonazepam
- CAS No.
- 58662-84-3
- Chemical Name
- Meclonazepam
- Synonyms
- Ro-11-3128;Meclonazepam;Meclonazepamum;Meclonazepam solution;Meclonazepam, 3-Methylclonazepam;(3S)-5-(2-chlorophenyl)-3-methyl-7-nitro-1,3-dihydro-1,4-benzodiazepin-2-one;(S)-5-(2-Chlorophenyl)-1,3-dihydro-3-methyl-7-nitro-2H-1,4-benzodiazepin-2-one;(3S)-5-(2-Chlorophenyl)-1,3-dihydro-3-methyl-7-nitro-2H-1,4-benzodiazepin-2-one;2H-1,4-Benzodiazepin-2-one, 5-(2-chlorophenyl)-1,3-dihydro-3-methyl-7-nitro-, (3S)-
- CBNumber
- CB11179106
- Molecular Formula
- C16H12ClN3O3
- Formula Weight
- 329.74
- MOL File
- 58662-84-3.mol
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Meclonazepam Property
- Boiling point:
- 522.1±50.0 °C(Predicted)
- Density
- 1.46
- storage temp.
- -20°C
- solubility
- DMF: 25 mg/ml; DMSO: 25 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Methanol: 1 mg/ml
- form
- A crystalline solid
- pka
- 11.24±0.70(Predicted)
- color
- White to off-white
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 25110
- Product name
- Meclonazepam
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $79
- Updated
- 2023/06/20
Cayman Chemical
- Product number
- 25110
- Product name
- Meclonazepam
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $349
- Updated
- 2023/06/20
AK Scientific
- Product number
- 6102CJ
- Product name
- Meclonazepam
- Packaging
- 1mg
- Price
- $187
- Updated
- 2021/12/16
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Meclonazepam Chemical Properties,Usage,Production
Uses
Meclonazepam-d4, is the labeled analogue of Meclonazepam (M202790), a drug of a benzodiazepine class similar in structure to Clonazepam (C587080). It has sedative and anxiolytic properties. It has also shown to have anti-parasitic effects against the parasitic worm Schistosoma mansoni.
in vivo
Meclonazepam (0.1-5.6 mg/kg) exhibits anxiolytic effect in gerbils[1].
Meclonazepam (40 and 80 mg/kg) Has highly significant effect on the immature schistosomes[2].
| Animal Model: | Adult experimentally naive male Mongolian gerbils (Meriones unguiculatus)[1] |
| Dosage: | 0.1, 0.3, 1.0, 3.0, 5.6 mg/kg |
| Administration: | Administration intraperitoneally (IP) 5 min prior to training onset. |
| Result: | The ED50 of 0.77-0.78 mg/kg at the 5 min post-injection (p.i.). |
| Animal Model: | CB6F1 mice were infected with single-sex male S. mansoni cercariae 28 days before treatment[2] |
| Dosage: | 40 and 80 mg/kg |
| Administration: | Administered by gavage either as single drugs or in a sequence consisting of 1 dose of Praziquantel (PZQ), a 5-min interval, 1 dose of Ro, a 15-min interval, a second dose of PZQ. |
| Result: | PZQ had no significant effect on the immature schistosomes, whereas Ro 11-3128 was highly effective. |
IC 50
Schistosome
Meclonazepam Preparation Products And Raw materials
Raw materials
Preparation Products
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Meclonazepam Suppliers
58662-84-3, MeclonazepamRelated Search:
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7-AMINONITRAZEPAM
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