L-threo-.alpha.-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(2S,4R)-4-ethyl-2-piperidinylcarbonylamino-1-thio-, monohydrochloride Property

Melting point:

>198°C (dec.)

alpha 

D25 +176° (US 4278789); D25 +181°

storage temp. 

Hygroscopic, -20°C Freezer, Under Inert Atmosphere

solubility 

Methanol (Slightly), Water (Slightly)

form 

Solid

color 

White to Off-White

Stability:

Hygroscopic

Safety

Toxicity

LD50 i.p. in mice: 600 mg/kg (Birkenmeyer, 1984)

Hazard and Precautionary Statements (GHS)

L-threo-.alpha.-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(2S,4R)-4-ethyl-2-piperidinylcarbonylamino-1-thio-, monohydrochloride Chemical Properties,Usage,Production

Chemical Properties

White to Off-White Solid

Uses

Pirlimycin hydrochloride is a salt of the semi-synthetic tetracycline analogue, pirlimycin. The hydrochloride salt forms at the basic pipercolic acid moiety and is the preferred pharmaceutical formulation. Like other members of the lincosamide family, pirlimycin hydrochloride is a broad spectrum antibiotic with activity against anaerobic bacteria and protozoans. Pirlimycin hydrochloride acts by binding to the 23S ribosomal subunit, blocking protein synthesis. Pirlimycin hydrochloride has been less extensively researched than the older more established lincosamides.

Uses

Pirlimycin Hydrochloride is a semi-synthetic lincosaminide antibiotic. Pirlimycin Hydrochloride is a Clindamycin (C580115) is a semi-synthetic antibiotic prepared from Lincomycin.

Uses

Semi-synthetic lincosaminide antibiotic; structural analog of Clindamycin. Antibacterial.