CAROVERINEHYDROCHLORIDE

Product Name: CAROVERINEHYDROCHLORIDE
CAS No.: 55750-05-5
Chemical Name: CAROVERINEHYDROCHLORIDE
Synonyms: p 201-1;CAROVERINEHYDROCHLORIDE;Caroverine hydrochloride, 10 mM in DMSO;Caroverine hydrochloride >=98% (HPLC), solid;1-Diethylaminoethyl-3-(p-methoxybenzyl)-2-quinoxaone hydrochloride;1-(2-diethylaminoethyl)-3-[(4-methoxyphenyl)methyl]quinoxalin-2-one;1-(2-(Diethylamino)ethyl)-3-(4-methoxybenzyl)quinoxalin-2(1H)-one hydrochloride;2(1H)-Quinoxalinone, 1-(2-diethylamino)ethyl-3-(4-methoxybenzyl)-, hydrochloride;1-[2-(diethylamino)ethyl]-3-[(4-methoxyphenyl)methyl]quinoxalin-2-one,hydrochloride;1-(2-Diethylamino)ethyl-3-((4-methoxyphenyl)methyl)-2(1H)-quinoxalinone hydrochloride
CBNumber: CB11229665
Molecular Formula: C22H27N3O2
Formula Weight: 0
MOL File: 55750-05-5.mol

More

Less

CAROVERINEHYDROCHLORIDE Property

storage temp.: 2-8°C
solubility: DMSO: >10mg/mL
form: solid
color: White to off-white

More

Less

Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H302Harmful if swallowed

More

Less

N-Bromosuccinimide Price

Adipogen Life Sciences

Product number: CDX-C0258-M025
Product name: Caroverine hydrochloride
Purity: ≥99%(HPLC)
Packaging: 25mg
Price: $165
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0008329
Product name: CAROVERINE HYDROCHLORIDE
Purity: 95.00%
Packaging: 10MG
Price: $740.39
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0008329
Product name: CAROVERINE HYDROCHLORIDE
Purity: 95.00%
Packaging: 50MG
Price: $1324.32
Updated: 2021/12/16

DC Chemicals

Product number: DC44933
Product name: Caroverine hydrochloride
Purity: >98%
Packaging: 250mg
Price: $950
Updated: 2021/12/16

DC Chemicals

Product number: DC44933
Product name: Caroverine hydrochloride
Purity: >98%
Packaging: 1g
Price: $1900
Updated: 2021/12/16

More

Less

CAROVERINEHYDROCHLORIDE Chemical Properties,Usage,Production

Uses

Caroverine hydrochloride is a potent, competitive and reversible antagonist of NMDA and AMPA glutamate receptor. Caroverine hydrochloride is also an antioxidant and calcium-blocking agent that exhibits vasorelaxant action. Caroverine hydrochloride can be used for the research of inner ear tinnitus[1][2][3].

in vivo

Caroverine (1.44 mg/rat; s.c; 1.0 mL/h for 72 h) attenuates impulse noise-induced hearing loss in the rat^[4].

Animal Model:	Sprague-Dawley rats of either sex (250-300 g) received impulse noise exposure^[4]
Dosage:	1.44 mg/rat
Administration:	20 mg/mL; s.c. 1.0 mL/h for 72 h
Result:	Significantly protected the cochlea against impulse noise trauma.

References

[1] Chen Z, et, al. Pharmacokinetics of caroverine in the inner ear and its effects on cochlear function after systemic and local administrations in Guinea pigs. Audiol Neurootol. Jan-Feb 2003;8(1):49-56. DOI:10.1159/000067893
[2] Denk DM, et, al. Caroverine in tinnitus treatment. A placebo-controlled blind study. Acta Otolaryngol. 1997 Nov;117(6):825-30. DOI:10.3109/00016489709114208
[3] Ishida Y, et, al. Vasorelaxant action of caroverine fumarate (a quinoxaline derivative), a calcium-blocking agent. Br J Pharmacol. 1980;71(1):343-8. DOI:10.1111/j.1476-5381.1980.tb10945.x
[4] Duan M, et, al. Low-dose, long-term caroverine administration attenuates impulse noise-induced hearing loss in the rat. Acta Otolaryngol. 2006 Dec;126(11):1140-7. DOI:10.1080/00016480500540519

CAROVERINEHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

CAROVERINEHYDROCHLORIDE Suppliers

China 46 India 2 Switzerland 1 United States 4 Global 53

Finetech Industry Limited

Tel: 027-87465837 19945049750
Fax: 027-8777-2287
Email: sales@finetechnology-ind.com
Country: China
ProdList: 9637
Advantage: 58

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4768
Advantage: 55

Shanghaizehan biopharma technology co., Ltd.

Tel: 021-61350663 13052117465
Fax: 021-61350662
Email: sales@zehanbiopharma.com
Country: China
ProdList: 984
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8000
Advantage: 62

Zhengzhou Acme Chemical Co., Ltd.

Tel: 0371-0371-55629727 13323845623
Fax: 037155629727
Email: 2885676761@qq.com
Country: China
ProdList: 10110
Advantage: 58

Chuzhou KeMail Chemical Technology Co., Ltd

Tel: 0550-5196001 15000891977
Fax: 0550-5196001
Email: wj520wjxby@126.com
Country: China
ProdList: 1944
Advantage: 55

Suzhou Ryway Biotech Co., Ltd

Tel: 180-1316-0973
Fax: 0512-68236973
Email: rywaybio@gmail.com
Country: China
ProdList: 275
Advantage: 55

Jinan Yaoyan Pharmaceutical Co., Ltd.

Tel
Fax: -
Email: jnyaoyan@163.com
Country: China
ProdList: 3069
Advantage: 58

55750-05-5, CAROVERINEHYDROCHLORIDERelated Search:

CAROVERINEHYDROCHLORIDE

1-(2-diethylaminoethyl)-3-[(4-methoxyphenyl)methyl]quinoxalin-2-one

1-[2-(Diethylamino)ethyl]-3-[(4-methoxyphenyl)methyl]-2(1H)-quinoxalinone monohydrochloride

1-(2-Diethylamino)ethyl-3-((4-methoxyphenyl)methyl)-2(1H)-quinoxalinone hydrochloride

1-Diethylaminoethyl-3-(p-methoxybenzyl)-2-quinoxaone hydrochloride

2(1H)-Quinoxalinone, 1-(2-diethylamino)ethyl-3-(4-methoxybenzyl)-, hydrochloride

p 201-1

1-[2-(diethylamino)ethyl]-3-[(4-methoxyphenyl)methyl]quinoxalin-2-one,hydrochloride

Caroverine hydrochloride >=98% (HPLC), solid

NMDA,glutamate,calcium,Tinnex,tinnitus,vasorelaxant,antioxidant,Inhibitor,iGluR,inner,inhibit,Caroverine hydrochloride,ear,Ionotropic glutamate receptors,AMPA,Caroverine

1-(2-(Diethylamino)ethyl)-3-(4-methoxybenzyl)quinoxalin-2(1H)-one hydrochloride

Caroverine hydrochloride, 10 mM in DMSO

55750-05-5

APIs