7-CHLORO-1,3DIHYDRO-5-FLUOROPHENYL-2-NITRO-METHYLENE-2H-1,4-BENZODIAZEPINE-4-OXIDE

Product Name: 7-CHLORO-1,3DIHYDRO-5-FLUOROPHENYL-2-NITRO-METHYLENE-2H-1,4-BENZODIAZEPINE-4-OXIDE
CAS No.: 60656-76-0
Chemical Name: 7-CHLORO-1,3DIHYDRO-5-FLUOROPHENYL-2-NITRO-METHYLENE-2H-1,4-BENZODIAZEPINE-4-OXIDE
Synonyms: Midazolam Impurity;Midazolam Impurity 11;Midazolam Impurity 26;MIDAZOLAM NITROMETHYLENE COMPOUND;7-CHLORO-1,3DIHYDRO-5-FLUOROPHENYL-2-NITRO-METHYLENE-2H-1,4-BENZODIAZEPINE-4-OXIDE;7-Chloro-1,3-dihydro-5-(2-fluorophenyl)-2-nitromethylene-2H-1,4-benzodiazepine 4-Oxide;7-Chloro-1,3-dihydro-2-nitromethylene-5-(2-fluorophenyl)-2H -1,4-benzodiazepine-4-oxide;7-Chloro-5-(2-fluorophenyl)-2,3-dihydro-2-(nitromethylene)-1H-1,4-benzodiazepine 4-Oxide;1H-1,4-Benzodiazepine, 7-chloro-5-(2-fluorophenyl)-2,3-dihydro-2-(nitromethylene)-, 4-oxide;7-chloro-5-(2-fluorophenyl)-2-(nitromethylene)-2,3-dihydro-1H-benzo[e][1,4]diazepine 4-oxide
CBNumber: CB11230968
Molecular Formula: C16H11ClFN3O3
Formula Weight: 347.73
MOL File: 60656-76-0.mol

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7-CHLORO-1,3DIHYDRO-5-FLUOROPHENYL-2-NITRO-METHYLENE-2H-1,4-BENZODIAZEPINE-4-OXIDE Property

Melting point:: 240-243 °C(Solv: N,N-dimethylformamide (68-12-2); water (7732-18-5))
Boiling point:: 539.7±60.0 °C(Predicted)
Density: 1.49±0.1 g/cm3(Predicted)
pka: -1.18±0.20(Predicted)
InChI: InChI=1S/C16H11ClFN3O3/c17-10-5-6-15-13(7-10)16(12-3-1-2-4-14(12)18)20(22)8-11(19-15)9-21(23)24/h1-7,9,19H,8H2
InChIKey: YFNLLWWUWXVJOM-UHFFFAOYSA-N
SMILES: N1C2=CC=C(Cl)C=C2C(C2=CC=CC=C2F)=[N+]([O-])CC1=C[N+]([O-])=O

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Hazard and Precautionary Statements (GHS)

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7-CHLORO-1,3DIHYDRO-5-FLUOROPHENYL-2-NITRO-METHYLENE-2H-1,4-BENZODIAZEPINE-4-OXIDE Chemical Properties,Usage,Production

Uses

7-Chloro-5-(2-fluorophenyl)-2,3-dihydro-2-(nitromethylene)-1H-1,4-benzodiazepine 4-Oxide is the synthetic precursor of Midazolam (M343000), an anesthetic, anticonvulsant, sedative and hypotic agent.

7-CHLORO-1,3DIHYDRO-5-FLUOROPHENYL-2-NITRO-METHYLENE-2H-1,4-BENZODIAZEPINE-4-OXIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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7-CHLORO-1,3DIHYDRO-5-FLUOROPHENYL-2-NITRO-METHYLENE-2H-1,4-BENZODIAZEPINE-4-OXIDE Suppliers

Canada 1 China 29 Germany 1 India 2 United States 2 Global 35

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60656-76-0, 7-CHLORO-1,3DIHYDRO-5-FLUOROPHENYL-2-NITRO-METHYLENE-2H-1,4-BENZODIAZEPINE-4-OXIDERelated Search:

N-desalkylflurazepam 2-AMINOMETHYL-7-CHLORO-2,3-DIHYDRO-5-(2-FLUOROPHENYL)-1H-1,4-BENZODIAZEPINE DIMALEATE 8-chloro-6-(o-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid 5,6-Dihydro Midazolam 8-Chloro-6-(2-fluorophenyl)-1-methyl-6H-Imidazo[1,5-a][1,4]benzodiazepine 8-Chloro-1-methyl-6-phenyl-4H-Imidazo[1,5-a][1,4]benzodiazepine 8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine 5-Oxide Midazolam 8-CHLORO-3A,4-DIHYDRO-6-(2-FLUOROPHENYL)-1-METHYL-3H-IMIDAZO[1,5-A][1,4]BENZO-DIAZEPINE Midazolam EP Impurity J 6-Chloro-2-methyl-4-(2-fluorophenyl)quinazoline

7-Chloro-5-(2-fluorophenyl)-2,3-dihydro-2-(nitromethylene)-1H-1,4-benzodiazepine 4-Oxide

7-Chloro-1,3dihydro-5-fluorophenyl-2-nitro-methylene-2H-1,4-benzodiazepine-4-oxide (Midazolam inte

Midazolam Impurity 11

(E)-7-chloro-5-(2-fluorophenyl)-2-(nitromethylene)-2,3-dihydro-1H-benzo[e][1,4]diazepine 4-oxide

1H-1,4-Benzodiazepine, 7-chloro-5-(2-fluorophenyl)-2,3-dihydro-2-(nitromethylene)-, 4-oxide

7-chloro-5-(2-fluorophenyl)-2-(nitromethylene)-2,3-dihydro-1H-benzo[e][1,4]diazepine 4-oxide

7-Chloro-1,3-dihydro-5-(2-fluorophenyl)-2-nitromethylene-2H-1,4-benzodiazepine 4-Oxide

7-Chloro-1,3-dihydro-2-nitromethylene-5-(2-fluorophenyl)-2H -1,4-benzodiazepine-4-oxide

Midazolam Impurity

MIDAZOLAM NITROMETHYLENE COMPOUND

7-CHLORO-1,3DIHYDRO-5-FLUOROPHENYL-2-NITRO-METHYLENE-2H-1,4-BENZODIAZEPINE-4-OXIDE

Midazolam Impurity 26

60656-76-0