4-Amino-5-chloro-N-(1-((4-fluorophenyl)methyl)-4-piperidinyl)-2-methox ybenzamide

ChemicalBook > CAS DataBase List > 4-Amino-5-chloro-N-(1-((4-fluorophenyl)methyl)-4-piperidinyl)-2-methox ybenzamide

4-Amino-5-chloro-N-(1-((4-fluorophenyl)methyl)-4-piperidinyl)-2-methox ybenzamide

Product Name: 4-Amino-5-chloro-N-(1-((4-fluorophenyl)methyl)-4-piperidinyl)-2-methox ybenzamide
CAS No.: 154540-49-5
Chemical Name: 4-Amino-5-chloro-N-(1-((4-fluorophenyl)methyl)-4-piperidinyl)-2-methox ybenzamide
Synonyms: fluoroclebopride;Fluoroclebopride, 10 mM in DMSO;Inhibitor,inhibit,Fluoroclebopride,Dopamine Receptor;4-Amino-5-chloro-N-(1-((4-fluorophenyl)methyl)-4-piperidinyl)-2-methox ybenzamide;Benzamide,4-amino-5-chloro-N-[1-[(4-fluorophenyl)methyl]-4-piperidinyl]-2-methoxy-
CBNumber: CB11242925
Molecular Formula: C20H23ClFN3O2
Formula Weight: 391.87
MOL File: 154540-49-5.mol

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4-Amino-5-chloro-N-(1-((4-fluorophenyl)methyl)-4-piperidinyl)-2-methox ybenzamide Property

Boiling point:: 518.2±50.0 °C(Predicted)
Density: 1.31±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF: 20 mg/ml; DMF:PBS (pH 7.2) (1:9): 0.1 mg/ml; DMSO: 10 mg/ml; Ethanol: 10 mg/ml
form: A crystalline solid
pka: 13.62±0.20(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 23447
Product name: Fluoroclebopride
Purity: ≥98%
Packaging: 1mg
Price: $37
Updated: 2024/03/01

Cayman Chemical

Product number: 23447
Product name: Fluoroclebopride
Purity: ≥98%
Packaging: 5mg
Price: $161
Updated: 2024/03/01

Cayman Chemical

Product number: 23447
Product name: Fluoroclebopride
Purity: ≥98%
Packaging: 10mg
Price: $283
Updated: 2024/03/01

AK Scientific

Product number: 9031CA
Product name: Fluoroclebopride
Packaging: 5mg
Price: $276
Updated: 2021/12/16

DC Chemicals

Product number: DC9669
Product name: Fluoroclebopride
Purity: >98%
Packaging: 100mg
Price: $500
Updated: 2021/12/16

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4-Amino-5-chloro-N-(1-((4-fluorophenyl)methyl)-4-piperidinyl)-2-methox ybenzamide Chemical Properties,Usage,Production

Description

Fluoroclebopride is a benzamide analog that is used in positron emission tomography (PET) applications. It binds reversibly to dopamine receptors (K_is = 0.95, 5.7, 5.46, and 144 nM for D₂-like, D_2(long), D₃, and D₄ receptors, respectively, in radioligand binding assays). It is selective for these receptors over D₁, serotonin 5-HT₂, and α₂-adrenergic receptors (K_is = >10,000, 283, and 1,300 nM, respectively). A fluorine-18 moiety has been used to label this compound for use as a probe for studying D₂/D₃ receptor availability via PET in various monkey models.

4-Amino-5-chloro-N-(1-((4-fluorophenyl)methyl)-4-piperidinyl)-2-methox ybenzamide Preparation Products And Raw materials

Raw materials

Preparation Products

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154540-49-5, 4-Amino-5-chloro-N-(1-((4-fluorophenyl)methyl)-4-piperidinyl)-2-methox ybenzamideRelated Search:

4-Amino-5-chloro-N-(1-((4-fluorophenyl)methyl)-4-piperidinyl)-2-methox ybenzamide

fluoroclebopride

Benzamide,4-amino-5-chloro-N-[1-[(4-fluorophenyl)methyl]-4-piperidinyl]-2-methoxy-

Inhibitor,inhibit,Fluoroclebopride,Dopamine Receptor

Fluoroclebopride, 10 mM in DMSO

154540-49-5

C20H23ClFN3O2