Flavipin

Product Name: Flavipin
CAS No.: 483-53-4
Chemical Name: Flavipin
Synonyms: 3,4,5-Trihydroxy-6-methyl-1,2-benzenedicarbaldehyde;1,2-Benzenedicarboxaldehyde, 3,4,5-trihydroxy-6-methyl-
CBNumber: CB11247809
Molecular Formula: C9H8O5
Formula Weight: 196.16
MOL File: 483-53-4.mol

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Flavipin Property

Melting point:: 233-234 °C (decomp)
Boiling point:: 353.7±42.0 °C(Predicted)
Density: 1.577±0.06 g/cm3(Predicted)
pka: 6.86±0.33(Predicted)

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Hazard and Precautionary Statements (GHS)

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Flavipin Chemical Properties,Usage,Production

Uses

Flavipin is an aryl hydrocarbon receptor (Ahr) agonist that induces the expression of Ahr downstream genes in mouse CD4+ T cells and CD11b+ macrophages. Flavipin inhibits the stabilizing function of Arid5a on Il23a 3′UTR, a newly identified target mRNA[1]. Flavipin exhibits the DPPH free radical scavenging ability with IC50 value of 7.2 μM, and has potent α-glucosidase inhibition with IC50 value of 33.8 μM[2].

References

[1] "Alzahrani A, et al. Differential modulation of Ahr and Arid5a: A promising therapeutic strategy for autoimmune encephalomyelitis. Saudi Pharm J. 2020;28(12):1605-1615. "
[2] Li H, et al. Polyketides from two Chaetomium species and their biological functions. J Antibiot (Tokyo). 2018;71(7):677-681. DOI:10.1038/s41429-018-0047-x

Flavipin Preparation Products And Raw materials

Raw materials

Preparation Products

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Flavipin Suppliers

CHINA 6 United States 3 Global 9

BOC Sciences

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TargetMol Chemicals Inc.

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HONEST JOY HOLDINGS LIMITED

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483-53-4, FlavipinRelated Search:

3,4,5-Trihydroxy-6-methyl-1,2-benzenedicarbaldehyde

1,2-Benzenedicarboxaldehyde, 3,4,5-trihydroxy-6-methyl-

483-53-4