2-METHYL-3-NITROIMIDAZO[1,2-A]PYRIDINE
- Product Name
- 2-METHYL-3-NITROIMIDAZO[1,2-A]PYRIDINE
- CAS No.
- 34165-09-8
- Chemical Name
- 2-METHYL-3-NITROIMIDAZO[1,2-A]PYRIDINE
- Synonyms
- 2-METHYL-3-NITROIMIDAZO[1,2-A]PYRIDINE;Imidazo[1,2-a]pyridine, 2-methyl-3-nitro-;2-Methyl-3-nitroimidazo[1,2-a]pyridine[N/A]
- CBNumber
- CB11253455
- Molecular Formula
- C8H7N3O2
- Formula Weight
- 177.16
- MOL File
- 34165-09-8.mol
2-METHYL-3-NITROIMIDAZO[1,2-A]PYRIDINE Property
- storage temp.
- 2-8°C
- Appearance
- Off-white to light yellow Solid
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 085990
- Product name
- 2-Methyl-3-nitroimidazo[1,2-a]pyridine
- Packaging
- 250.00mg
- Price
- $23
- Updated
- 2026/05/18
- Product number
- 085990
- Product name
- 2-Methyl-3-nitroimidazo[1,2-a]pyridine
- Packaging
- 1.00g
- Price
- $84
- Updated
- 2026/05/18
- Product number
- 085990
- Product name
- 2-Methyl-3-nitroimidazo[1,2-a]pyridine
- Packaging
- 5.00g
- Price
- $321
- Updated
- 2026/05/18
- Product number
- BD-A475626
- Product name
- 2-Methyl-3-nitroimidazo[1,2-a]pyridine
- Purity
- 97%
- Packaging
- 100mg
- Price
- $14
- Updated
- 2026/05/25
- Product number
- BD-A475626
- Product name
- 2-Methyl-3-nitroimidazo[1,2-a]pyridine
- Purity
- 97%
- Packaging
- 250mg
- Price
- $18
- Updated
- 2026/05/25
2-METHYL-3-NITROIMIDAZO[1,2-A]PYRIDINE Chemical Properties,Usage,Production
Synthesis
934-37-2
34165-09-8
General procedure for the synthesis of 2-methyl-3-nitroimidazo[1,2-a]pyridine from 2-methylimidazo[1,2-a]pyridine: to a cooled solution of 2-methylimidazo[1,2-a]pyridine (380 mg, 2.88 mmol) in concentrated sulfuric acid (6 mL) was slowly added nitric acid (472 μL, density = 1.38 g/mL) dropwise. The reaction mixture was stirred for 2 h at room temperature and then cooled in an ice bath, followed by slow addition of saturated aqueous Na2CO3 solution adjusted to alkaline. The reaction mixture was extracted with dichloromethane (CH2Cl2) and the organic layer was dried with anhydrous magnesium sulfate (MgSO4), filtered and concentrated under reduced pressure to give 330 mg (1.82 mmol, 65% yield) of 2-methyl-3-nitroimidazo[1,2-a]pyridine as a brown solid.LRMS (m/z): 178 ([M+H]+).
References
[1] Bioorganic and Medicinal Chemistry, 2013, vol. 21, # 22, p. 7155 - 7164
[2] Patent: EP2848615, 2015, A1. Location in patent: Paragraph 0099
[3] Chemical and Pharmaceutical Bulletin, 2001, vol. 49, # 12, p. 1631 - 1635
2-METHYL-3-NITROIMIDAZO[1,2-A]PYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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