(4aS,10aS)-6-hydroxy-1,1,4a-trimethyl-7-propan-2-yl-3,4,10,10a-tetrahy dro-2H-phenanthren-9-one

ChemicalBook > CAS DataBase List > (4aS,10aS)-6-hydroxy-1,1,4a-trimethyl-7-propan-2-yl-3,4,10,10a-tetrahy dro-2H-phenanthren-9-one

(4aS,10aS)-6-hydroxy-1,1,4a-trimethyl-7-propan-2-yl-3,4,10,10a-tetrahy dro-2H-phenanthren-9-one

Product Name: (4aS,10aS)-6-hydroxy-1,1,4a-trimethyl-7-propan-2-yl-3,4,10,10a-tetrahy dro-2H-phenanthren-9-one
CAS No.: 511-05-7
Chemical Name: (4aS,10aS)-6-hydroxy-1,1,4a-trimethyl-7-propan-2-yl-3,4,10,10a-tetrahy dro-2H-phenanthren-9-one
Synonyms: Sugiol;(+)-Sugiol;10-Deoxoxanthoperol;12-Hydroxyabieta-8,11,13-triene-7-one;(4aS)-2,3,4,4a,10,10aα-Hexahydro-6-hydroxy-1,1,4a-trimethyl-7-isopropylphenanthren-9(1H)-one;(4aS,10aS)-6-hydroxy-1,1,4a-trimethyl-7-propan-2-yl-3,4,10,10a-tetrahy dro-2H-phenanthren-9-one;9(1H)-Phenanthrenone, 2,3,4,4a,10,10a-hexahydro-6-hydroxy-1,1,4a-trimethyl-7-(1-methylethyl)-, (4aS,10aS)-
CBNumber: CB11254043
Molecular Formula: C20H28O2
Formula Weight: 300.44
MOL File: 511-05-7.mol

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(4aS,10aS)-6-hydroxy-1,1,4a-trimethyl-7-propan-2-yl-3,4,10,10a-tetrahy dro-2H-phenanthren-9-one Property

Melting point:: 290-292 °C (decomp)
Boiling point:: 185-205 °C(Press: 0.1 Torr)
Density: 1.049±0.06 g/cm3(Predicted)
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: Powder
pka: 8.71±0.60(Predicted)
LogP: 6.770 (est)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Arctom

Product number: CFN92187
Product name: Sugiol
Packaging: 5mg
Price: $510
Updated: 2021/12/16

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(4aS,10aS)-6-hydroxy-1,1,4a-trimethyl-7-propan-2-yl-3,4,10,10a-tetrahy dro-2H-phenanthren-9-one Chemical Properties,Usage,Production

Definition

ChEBI: Sugiol is an abietane diterpenoid that is ferruginol in which the methylene group para to the phenolic hydroxy group has been substituted by an oxo group. It has a role as a plant metabolite, an antiviral agent, an antineoplastic agent, an antioxidant and a radical scavenger. It is an abietane diterpenoid, a carbotricyclic compound, a meroterpenoid, a member of phenols and a cyclic terpene ketone. It is functionally related to a ferruginol.

Cytotoxicity

IC50 (μg/mL): <50 (SW620, HCT116,MDA-MB-231, NCI-H23, and A549)(Son et al. 2005)
IC50 (μg/mL): >30.04 (MRC-5, PC-3),23.98 (A549), 20.62 (Hl-60), 26.4(PANC-1), 10.82 (BxPC-3) (Li et al.2013).

target

ROS | IL Receptor | TNF-α | MAPK | ERK | JNK | p38MAPK

(4aS,10aS)-6-hydroxy-1,1,4a-trimethyl-7-propan-2-yl-3,4,10,10a-tetrahy dro-2H-phenanthren-9-one Preparation Products And Raw materials

Raw materials

Preparation Products

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511-05-7, (4aS,10aS)-6-hydroxy-1,1,4a-trimethyl-7-propan-2-yl-3,4,10,10a-tetrahy dro-2H-phenanthren-9-oneRelated Search:

(4aS,10aS)-6-hydroxy-1,1,4a-trimethyl-7-propan-2-yl-3,4,10,10a-tetrahy dro-2H-phenanthren-9-one

(+)-Sugiol

(4aS)-2,3,4,4a,10,10aα-Hexahydro-6-hydroxy-1,1,4a-trimethyl-7-isopropylphenanthren-9(1H)-one

12-Hydroxyabieta-8,11,13-triene-7-one

Sugiol

10-Deoxoxanthoperol

9(1H)-Phenanthrenone, 2,3,4,4a,10,10a-hexahydro-6-hydroxy-1,1,4a-trimethyl-7-(1-methylethyl)-, (4aS,10aS)-

511-05-7