4-Bromo-N-methylbenzamide 98%
- Product Name
- 4-Bromo-N-methylbenzamide 98%
- CAS No.
- 27466-83-7
- Chemical Name
- 4-Bromo-N-methylbenzamide 98%
- Synonyms
- p-Bromo-N-methylbenzamide;N-Methyl-p-bromobenzamide;N-Methyl 4-bromobenzamide;4-Bromo-N-methylbenzamide;benzamide, 4-bromo-N-methyl-;4-Bromo-N-methylbenzamide 98%;4-Bromo-N-methylbenzamide 98%;4-bromo-N-methylbenzamide(SALTDATA: FREE)
- CBNumber
- CB11262961
- Molecular Formula
- C8H8BrNO
- Formula Weight
- 214.06
- MOL File
- 27466-83-7.mol
4-Bromo-N-methylbenzamide 98% Property
- Melting point:
- 173-174℃
- Boiling point:
- 329.8±25.0 °C(Predicted)
- Density
- 1.67 g/cm3
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 14.63±0.46(Predicted)
- form
- solid
- color
- White to off-white
- InChI
- 1S/C8H8BrNO/c1-10-8(11)6-2-4-7(9)5-3-6/h2-5H,1H3,(H,10,11)
- InChIKey
- DXCFWNVWQTYPOC-UHFFFAOYSA-N
- SMILES
- CNC(=O)c1ccc(Br)cc1
- CAS DataBase Reference
- 27466-83-7
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- CDS003953
- Product name
- 4-Bromo-N-methylbenzamide
- Purity
- Aldrich<SUP>CPR</SUP>
- Packaging
- 250 mg
- Price
- $77.9
- Updated
- 2026/04/30
- Product number
- M296120
- Product name
- N-Methyl4-bromobenzamide
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- M296120
- Product name
- N-Methyl4-bromobenzamide
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- FB121738
- Product name
- 4-Bromo-N-methylbenzamide
- Packaging
- 500mg
- Price
- $100
- Updated
- 2021/12/16
- Product number
- 4648-9-07
- Product name
- 4-Bromo-N-methylbenzamide
- Purity
- 98%
- Packaging
- 1g
- Price
- $112
- Updated
- 2021/12/16
4-Bromo-N-methylbenzamide 98% Chemical Properties,Usage,Production
Synthesis
586-75-4
74-89-5
27466-83-7
The general procedure for the synthesis of N-methyl-4-bromobenzamide from 4-bromobenzoyl chloride and monomethylamine was as follows: 4-bromobenzoyl chloride (5.0 g, 22.8 mmol) was dissolved in dichloromethane (DCM, 100 mL), followed by the addition of triethylamine (TEA, 7.0 mL, 50.2 mmol). A THF solution of methylamine (20 mL, 2.0 N) was added slowly and dropwise with stirring. The reaction mixture was stirred for 1 h at room temperature and then the reaction was quenched with 2.0 N hydrochloric acid (50 mL). The reaction mixture was extracted with dichloromethane (2 x 100 mL) and the organic phases were combined and dried over anhydrous sodium sulfate. The solvent was removed by concentration under reduced pressure to give the white solid product N-methyl-4-bromobenzamide (4.8 g, 98% yield). The product was confirmed by NMR hydrogen spectrum (299.954 MHz, CDCl3): δ 7.62 (d, 2H), 7.55 (d, 2H), 6.16 (s, 3H), 3.00 (d, 6H); mass spectrum (m/z): 215.
References
[1] Patent: WO2006/64251, 2006, A1. Location in patent: Page/Page column 60-61
[2] Journal of Medicinal Chemistry, 2018, vol. 61, # 11, p. 4860 - 4882
[3] Tetrahedron, 1973, vol. 29, p. 1073 - 1081
[4] Patent: US5654299, 1997, A
[5] Tetrahedron Letters, 2008, vol. 49, # 11, p. 1725 - 1728
4-Bromo-N-methylbenzamide 98% Preparation Products And Raw materials
Raw materials
Preparation Products
4-Bromo-N-methylbenzamide 98% Suppliers
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44802
- Advantage
- 61
- Tel
- 86-027-67849912
- Fax
- 86-027-87531808
- sales@chemwish.com
- Country
- China
- ProdList
- 35896
- Advantage
- 56
- Tel
- 021-50795510 4000665055
- Fax
- 021-50795055
- marketing@accelachem.com
- Country
- China
- ProdList
- 10977
- Advantage
- 64
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42934
- Advantage
- 64
- Tel
- Please Send Email 18652950785
- Fax
- 025-87193546
- chemweiao@163.com
- Country
- China
- ProdList
- 4378
- Advantage
- 65
- Tel
- 028-85114309 18982182443
- yangli@happysyn.com
- Country
- China
- ProdList
- 2236
- Advantage
- 55
- Tel
- 021-58170097
- info@topbiochem.com
- Country
- China
- ProdList
- 9520
- Advantage
- 58
- Tel
- 025-66113011 17714375163
- Fax
- (1)02557626880
- cfzhang@aikonchem.com
- Country
- China
- ProdList
- 19906
- Advantage
- 55
- Tel
- 15026594951
- Fax
- 0556-5030632
- rs@raise-chem.com
- Country
- China
- ProdList
- 4712
- Advantage
- 55
View Lastest Price from 4-Bromo-N-methylbenzamide 98% manufacturers
- Product
- Apalutamide Impurity 51 27466-83-7
- Price
- US $0.00-0.00/mg
- Min. Order
- 10mg
- Purity
- 99%+ HPLC
- Supply Ability
- 1000
- Release date
- 2025-05-26
- Product
- 4-Bromo-N-methylbenzamide 98% 27466-83-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- Customized
- Release date
- 2019-05-25