1H-Pyrazole-3-carboxylicacid,4-formyl-,ethylester(9CI)
- Product Name
- 1H-Pyrazole-3-carboxylicacid,4-formyl-,ethylester(9CI)
- CAS No.
- 179692-09-2
- Chemical Name
- 1H-Pyrazole-3-carboxylicacid,4-formyl-,ethylester(9CI)
- Synonyms
- ethyl 4-formyl-1H-pyrazole-3-carboxylate;methyl 4-formyl-1H-pyrazole-3-carboxylate;Albb-007090;ethyl 4-formyl-2H-pyrazole-3-carboxylate;ethyl 4-formyl-1H-pyrazol-3(5)-carboxylate;ethyl 4-methanoyl-2H-pyrazole-3-carboxylate;Ethyl 4-formyl-1H-pyrazole-3-carboxylic acid;4-Formyl-1H-pyrazol-3-carboxylic acid ethyl ester;4-formyl-2H-pyrazole-3-carboxylic acid ethyl ester;4-Formyl-1H-pyrazole-3-carboxylic acid ethyl ester
- CBNumber
- CB11273411
- Molecular Formula
- C7H8N2O3
- Formula Weight
- 168.15
- MOL File
- 179692-09-2.mol
1H-Pyrazole-3-carboxylicacid,4-formyl-,ethylester(9CI) Property
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
Safety
- HS Code
- 2933199090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- E939803
- Product name
- Ethyl4-Formyl-1H-pyrazole-3-carboxylate
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- OR953463
- Product name
- Ethyl4-formyl-1H-pyrazole-3-carboxylate
- Purity
- 98%
- Packaging
- 250mg
- Price
- $150
- Updated
- 2021/12/16
- Product number
- 027252
- Product name
- Ethyl 4-formyl-1H-pyrazole-5-carboxylate
- Packaging
- 500mg
- Price
- $163
- Updated
- 2021/12/16
- Product number
- 6015AD
- Product name
- Ethyl4-formyl-1H-pyrazole-5-carboxylate
- Packaging
- 1g
- Price
- $178
- Updated
- 2021/12/16
- Product number
- OR953463
- Product name
- Ethyl4-formyl-1H-pyrazole-3-carboxylate
- Purity
- 98%
- Packaging
- 1g
- Price
- $310
- Updated
- 2021/12/16
1H-Pyrazole-3-carboxylicacid,4-formyl-,ethylester(9CI) Chemical Properties,Usage,Production
Synthesis
68-12-2
14923-66-1
179692-09-2
Example 55B. Synthesis of ethyl 4-formyl-1H-pyrazole-3-carboxylate: Phosphoryl chloride (14.6 g, 95 mmol) was added dropwise to dry N,N-dimethylformamide (15 mL) at 0 °C under argon protection and stirred for 30 min. Subsequently, Example 55A (2.8 g, 16 mmol) was added in batches at 0 °C. The resulting orange solution was slowly warmed to room temperature and stirred at 60 °C for 4 hours. Upon completion of the reaction, the mixture was cooled to room temperature and poured into crushed ice. The pH was adjusted with 3N NaOH solution to about 6. The mixture was heated at 60 °C for 5 min and then cooled to room temperature. After standing at room temperature overnight, the solid was collected by filtration to give the target product Example 55B (1.5 g, 55% yield). The product was analyzed by LC-MS, [M + H]+ = 169. 1H NMR (DMSO-d6, 400 MHz) δ 14.19 (br.s, 1H), 10.26 (s, 1H), 8.43 (br.s, 1H), 4.37 (q, J = 7.2 Hz, 2H), 1.34 (t, J = 7.2 Hz, 3H).
References
[1] Patent: WO2010/47956, 2010, A1. Location in patent: Page/Page column 132
[2] Patent: US2016/237059, 2016, A1. Location in patent: Paragraph 0
1H-Pyrazole-3-carboxylicacid,4-formyl-,ethylester(9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
View Lastest Price from 1H-Pyrazole-3-carboxylicacid,4-formyl-,ethylester(9CI) manufacturers
- Product
- 1H-Pyrazole-3-carboxylicacid,4-formyl-,ethylester(9CI) 179692-09-2
- Price
- US $6.60/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 1kg-1000kg
- Release date
- 2019-12-30