2-Pyrimidinecarboxylicacid,5-methyl-,methylester(6CI,9CI)
Uses- Product Name
- 2-Pyrimidinecarboxylicacid,5-methyl-,methylester(6CI,9CI)
- CAS No.
- 76196-80-0
- Chemical Name
- 2-Pyrimidinecarboxylicacid,5-methyl-,methylester(6CI,9CI)
- Synonyms
- Methyl5-methylpyrimidine-2-carboxylate;5-methylpyrimidine-2-carboxylic acidmethyl ester;5-Methyl-2-pyrimidinecarboxylic acid methyl ester;2-PyriMidinecarboxylicacid,5-Methyl-,Methylester(6;2-Pyrimidinecarboxylicacid,5-methyl-,methylester(6CI,9CI);2-Pyrimidinecarboxylicacid,5-methyl-,methylester(6CI,9CI) ISO 9001：2015 REACH
- CBNumber
- CB11279569
- Molecular Formula
- C7H8N2O2
- Formula Weight
- 152.15
- MOL File
- 76196-80-0.mol
2-Pyrimidinecarboxylicacid,5-methyl-,methylester(6CI,9CI) Property
- Melting point:
- 99-101℃
- Boiling point:
- 270℃
- Density
- 1.169
- Flash point:
- 117℃
- storage temp.
- 2-8°C
- form
- solid
- pka
- -0.99±0.22(Predicted)
- Appearance
- Light yellow to light brown Solid
- InChI
- 1S/C7H8N2O2/c1-5-3-8-6(9-4-5)7(10)11-2/h3-4H,1-2H3
- InChIKey
- WBEDYPRLVFMBSD-UHFFFAOYSA-N
- SMILES
- CC1=CN=C(C(OC)=O)N=C1
- CAS DataBase Reference
- 76196-80-0
Safety
- HS Code
- 2933599590
- Storage Class
- 11 - Combustible Solids
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- PHB00068
- Product name
- Methyl 5-methylpyrimidine-2-carboxylate
- Purity
- AldrichCPR
- Packaging
- 1 g
- Price
- $403
- Updated
- 2025/07/31
- Product number
- B451568
- Product name
- Methyl5-Methylpyrimidine-2-carboxylate
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- B451568
- Product name
- Methyl5-Methylpyrimidine-2-carboxylate
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 1964AQ
- Product name
- METHYL5-METHYLPYRIMIDINE-2-CARBOXYLATE
- Packaging
- 100mg
- Price
- $210.8
- Updated
- 2021/12/16
- Product number
- OR924529
- Product name
- Methyl5-methylpyrimidine-2-carboxylate
- Purity
- 95%
- Packaging
- 250mg
- Price
- $225
- Updated
- 2021/12/16
2-Pyrimidinecarboxylicacid,5-methyl-,methylester(6CI,9CI) Chemical Properties,Usage,Production
Uses
5-Methyl-2-pyrimidinecarboxylic acid methyl ester can be used as a pharmaceutical synthesis intermediate.
Synthesis
Synthesis of 2-Pyrimidinecarboxylicacid,5-methyl-,methylester(6CI,9CI): to a stirred solution of 2-chloro-5-methylpyrimidine (200 mg, 1.55 mmol) in MeOH:CH3CN (4:1, 10 mL) under argon atmosphere was added Pd(dppf)Cl2 (227 mg, 0.31 mmol) and triethylamine (0.45 mL, 3.11 mmol ) at room temperature; heated to 100 C and stirred in a steel bomb for 16 h under CO pressure. The reaction was monitored by TLC; after completion of the reaction, the reaction mixture was filtered through diatomaceous earth and the filtrate was concentrated in vacuum to give the crude product methyl 5-methyl-2-pyrimidinecarboxylate. The crude product was purified by silica gel column chromatography using 60% EtOAc/hexane as methyl 5-methyl-2-pyrimidinecarboxylate (146 mg, 62%) as a brick red solid.
2-Pyrimidinecarboxylicacid,5-methyl-,methylester(6CI,9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Pyrimidinecarboxylicacid,5-methyl-,methylester(6CI,9CI) manufacturers
- Product
- 2-Pyrimidinecarboxylicacid,5-methyl-,methylester(6CI,9CI) 76196-80-0
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-05-12