Methyl (1S,4R)-4-Amino-2-Cyclopentene-1-Carboxylate
- Product Name
- Methyl (1S,4R)-4-Amino-2-Cyclopentene-1-Carboxylate
- CAS No.
- 138923-03-2
- Chemical Name
- Methyl (1S,4R)-4-Amino-2-Cyclopentene-1-Carboxylate
- Synonyms
- (1S,4R)-Methyl 4-aMinocyclopent-2-enecarboxylate;methyl (1S,4R)-4-aminocyclopent-2-ene-1-carboxylate;Methyl (1S,4R)-4-Amino-2-Cyclopentene-1-Carboxylate;(1S,4R)-2-CYCLOPENTENE-1-CARBOXYLIC ACID, 4-AMINOMETHYL ESTER;(1S,4R)-Methyl 4-aMinocyclopent-2-enecarboxylate L-tartrate salt;Cis-(1S,4R)-4-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester;2-Cyclopentene-1-carboxylicacid,4-amino-,methylester,(1S,4R)-(9CI);2-Cyclopentene-1-carboxylic acid, 4-amino-, methyl ester, (1S,4R)-;methyl (1S,4R)-4-aminocyclopent-2-ene-1-carboxylate hydrogen chloride
- CBNumber
- CB11286228
- Molecular Formula
- C7H11NO2
- Formula Weight
- 141.17
- MOL File
- 138923-03-2.mol
Methyl (1S,4R)-4-Amino-2-Cyclopentene-1-Carboxylate Property
- Boiling point:
- 191.9±40.0 °C(Predicted)
- Density
- 1.109±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 9.66±0.40(Predicted)
N-Bromosuccinimide Price
- Product number
- CCH0032340
- Product name
- (1S,4R)-METHYL 4-AMINOCYCLOPENT-2-ENECARBOXYLATE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $501.53
- Updated
- 2021/12/16
- Product number
- CCH0032340
- Product name
- (1S,4R)-METHYL 4-AMINOCYCLOPENT-2-ENECARBOXYLATE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $1575
- Updated
- 2021/12/16
- Product number
- CD13023343
- Product name
- (1S,4R)-Methyl4-aminocyclopent-2-enecarboxylate
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $333
- Updated
- 2021/12/16
- Product number
- CD13023343
- Product name
- (1S,4R)-Methyl4-aminocyclopent-2-enecarboxylate
- Purity
- 95+%
- Packaging
- 1g
- Price
- $832
- Updated
- 2021/12/16
Methyl (1S,4R)-4-Amino-2-Cyclopentene-1-Carboxylate Chemical Properties,Usage,Production
Uses
Methyl (1S,4R)-4-Amino-2-Cyclopentene-1-Carboxylate is used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
Synthesis
Weigh 50g of the by-product (+)1-amino-4-carboxy-2-cyclopentene extracted by γ-lactam enzymatic resolution and put it in a flask, add 200g of water, and slowly add dropwise at 25~30℃ Sulfuric acid, adjust the pH value of the solution to 1~2, after the dripping is completed, add 0.1g of the racemic catalyst o-phthalaldehyde, then heat to reflux, and react for 10~15h. Concentrate under reduced pressure to no fraction, add 200ml of methanol, 20g of tartaric acid, cool to 10-20°C, filter and wash with methanol. Then add 20g of thionyl chloride and 100ml of methanol to the filter cake, react at 65°C for 8h and concentrate under reduced pressure until there is no fraction. Add 100ml of dichloromethane, stir to dissolve and wash the dichloromethane layer twice with drinking water to obtain (- ) Methyl 1-amino-4-carboxylate-2-cyclopentene in dichloromethane solution, yield 42%.
Methyl (1S,4R)-4-Amino-2-Cyclopentene-1-Carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
Methyl (1S,4R)-4-Amino-2-Cyclopentene-1-Carboxylate Suppliers
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- Country
- United States
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