1H-Pyrazole-3-carboxylicacid,4-chloro-(9CI)
- Product Name
- 1H-Pyrazole-3-carboxylicacid,4-chloro-(9CI)
- CAS No.
- 84547-87-5
- Chemical Name
- 1H-Pyrazole-3-carboxylicacid,4-chloro-(9CI)
- Synonyms
- 4-Chloropyrazole-3-carboxylic Acid;4-Chloro-3-pyrazolecarboxylic acid;1H-Pyrazole-3-carboxylic acid, 4-chloro-;1H-pyrazole-5-carboxylic acid, 4-chloro-;1H-Pyrazole-3-carboxylicacid,4-chloro-(9CI);4-Chloro-1H-pyrazole-3-carboxylic acid;4-chloro-1H-pyrazole-3-carboxylic acid(SALTDATA: FREE)
- CBNumber
- CB11299499
- Molecular Formula
- C4H3ClN2O2
- Formula Weight
- 146.53
- MOL File
- 84547-87-5.mol
1H-Pyrazole-3-carboxylicacid,4-chloro-(9CI) Property
- Melting point:
- 255-260°C
- Boiling point:
- 389.8±22.0 °C(Predicted)
- Density
- 1.714±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- form
- solid
- pka
- 2.70±0.25(Predicted)
- color
- White to off-white
- InChI
- 1S/C4H3ClN2O2/c5-2-1-6-7-3(2)4(8)9/h1H,(H,6,7)(H,8,9)
- InChIKey
- ZOLUACWHRMUETA-UHFFFAOYSA-N
- SMILES
- OC(=O)c1n[nH]cc1Cl
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 736740
- Product name
- 4-Chloro-1H-pyrazole-3-carboxylic acid
- Purity
- 95%
- Packaging
- 250mg
- Price
- $84
- Updated
- 2023/01/07
- Product number
- C422033
- Product name
- 4-Chloro-1H-pyrazole-3-carboxylic acid
- Packaging
- 100mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- FC10784
- Product name
- 4-Chloro-1H-pyrazole-3-carboxylic acid
- Packaging
- 250mg
- Price
- $87.5
- Updated
- 2021/12/16
- Product number
- 027390
- Product name
- 4-Chloro-1H-pyrazole-3-carboxylic acid
- Packaging
- 500mg
- Price
- $103
- Updated
- 2021/12/16
- Product number
- W8728
- Product name
- 4-Chloro-1H-pyrazole-3-carboxylic acid
- Packaging
- 250mg
- Price
- $103
- Updated
- 2021/12/16
1H-Pyrazole-3-carboxylicacid,4-chloro-(9CI) Chemical Properties,Usage,Production
Synthesis
98816-35-4
84547-87-5
A mixture of 4-chloro-3-methylpyrazole hydrochloride (20 mmol, 3.06 g; see step (a)) with potassium permanganate (50 mmol, 11.4 g) in 500 mL of water was stirred thoroughly. The mixture was first stirred at room temperature for 3 days, then warmed up to 70 °C and continued stirring for 5 hours. After completion of the reaction, the mixture was filtered and the filtrate was concentrated. To the concentrate was added 1 M aqueous hydrochloric acid (50 mL) followed by extraction with ethyl acetate (5 x 50 mL). The organic phases were combined, washed with saturated aqueous sodium chloride, dried over anhydrous sodium sulfate and concentrated to give 640 mg (22% yield) of the target product 4-chloro-1H-pyrazole-5-carboxylic acid as a white solid.1H NMR (DMSO-d6, 400 MHz) δ 13.47 (br s, 2H), 7.92 (br s, 1H).
References
[1] Patent: WO2007/45868, 2007, A1. Location in patent: Page/Page column 49
[2] Patent: WO2007/51981, 2007, A1. Location in patent: Page/Page column 52
1H-Pyrazole-3-carboxylicacid,4-chloro-(9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
1H-Pyrazole-3-carboxylicacid,4-chloro-(9CI) Suppliers
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 001-857-928-2050 or 1-888-588-9418
- Fax
- 001-617-206-9595
- sales@chemreagents.com
- Country
- United States
- ProdList
- 10186
- Advantage
- 62
- Tel
- 86-0571-85151182
- Fax
- 86-0571-85151182
- Country
- China
- ProdList
- 5691
- Advantage
- 66
- Tel
- 025-58395930
- Fax
- 025-5861-9182
- sales@acornpharma.com
- Country
- China
- ProdList
- 982
- Advantage
- 60
- Tel
- 021-61312847 13636370518
- Fax
- 021-55068248
- shyysw007@163.com
- Country
- China
- ProdList
- 4999
- Advantage
- 60
- Tel
- +86 21 61551611
- Fax
- +86 21 50676805
- Country
- China
- ProdList
- 9891
- Advantage
- 58
- Tel
- 4009209199
- Fax
- 86-021-52271987
- sales@9dingchem.com
- Country
- China
- ProdList
- 18209
- Advantage
- 56
- Tel
- 400-400-164-7117 18317119277
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 40000
- Advantage
- 60
- Tel
- 0731-88827538 15873153880
- Fax
- 0731-88827238
- luxingbc@126.com
- Country
- China
- ProdList
- 1997
- Advantage
- 65
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
- Country
- China
- ProdList
- 51395
- Advantage
- 80
View Lastest Price from 1H-Pyrazole-3-carboxylicacid,4-chloro-(9CI) manufacturers
- Product
- 4-Chloro-1H-pyrazole-5-carboxylic acid 84547-87-5
- Price
- US $1.60-6.60/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-06-19
- Product
- 1H-Pyrazole-3-carboxylicacid,4-chloro-(9CI) 84547-87-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2019-12-26