ChemicalBook > CAS DataBase List > 1H-Isoindol-1-one,2,3-dihydro-4-methoxy-(9CI)

1H-Isoindol-1-one,2,3-dihydro-4-methoxy-(9CI)

Product Name
1H-Isoindol-1-one,2,3-dihydro-4-methoxy-(9CI)
CAS No.
366453-22-7
Chemical Name
1H-Isoindol-1-one,2,3-dihydro-4-methoxy-(9CI)
Synonyms
4-Methoxy-2,3-dihydro-isoindol-1-one;2,3-Dihydro-4-methoxy-1H-isoindol-1-one;4-Methoxy-2,3-dihydro-1H-isoindol-1-one;1H-Isoindol-1-one, 2,3-dihydro-4-Methoxy-;1H-Isoindol-1-one,2,3-dihydro-4-methoxy-(9CI)
CBNumber
CB11301637
Molecular Formula
C9H9NO2
Formula Weight
163.17
MOL File
366453-22-7.mol
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1H-Isoindol-1-one,2,3-dihydro-4-methoxy-(9CI) Property

Melting point:
>200 °C
Boiling point:
439.2±45.0 °C(Predicted)
Density 
1.208±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
14.37±0.20(Predicted)
Appearance
White to off-white Solid
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Safety

HS Code 
2925199590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TRC
Product number
M341305
Product name
4-Methoxyisoindolin-1-one
Packaging
50mg
Price
$45
Updated
2021/12/16
AK Scientific
Product number
Z4658
Product name
4-Methoxyisoindolin-1-one
Packaging
1g
Price
$195
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0150678
Product name
4-METHOXY-2,3-DIHYDRO-ISOINDOL-1-ONE
Purity
96.00%
Packaging
5MG
Price
$501.62
Updated
2021/12/16
Matrix Scientific
Product number
126606
Product name
4-Methoxyisoindolin-1-one
Purity
>95%
Packaging
1g
Price
$1386
Updated
2021/12/16
J&W Pharmlab
Product number
48R0307
Product name
4-Methoxy-2,3-dihydro-isoindol-1-one
Purity
95%
Packaging
25g
Price
$1420
Updated
2021/12/16
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1H-Isoindol-1-one,2,3-dihydro-4-methoxy-(9CI) Chemical Properties,Usage,Production

Synthesis

71887-28-0

366453-22-7

Step b: A mixed solution of methyl 2-bromomethyl-3-methoxybenzoate (997 mg, 3.85 mmol) and ammonium hydroxide (9 mL) in THF (19 mL) was reacted with stirring at room temperature for 4 hours. After completion of the reaction, the reaction mixture was concentrated to dryness under reduced pressure. The resulting residue was purified by fast column chromatography (eluent: hexane/ethyl acetate, 40/60 with 1% methanol) to afford 4-methoxyisoindolin-1-one as a white solid (595 mg, 95% yield).

References

[1] Chinese Chemical Letters, 2012, vol. 23, # 1, p. 9 - 12
[2] Patent: WO2004/26875, 2004, A1. Location in patent: Page 38
[3] Patent: US2004/106791, 2004, A1. Location in patent: Page 9
[4] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 2, p. 814 - 819

1H-Isoindol-1-one,2,3-dihydro-4-methoxy-(9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 1H-Isoindol-1-one,2,3-dihydro-4-methoxy-(9CI) manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
4-Methoxyisoindolin-1-one 366453-22-7
Price
US $0.00-0.00/KG
Min. Order
5mg
Purity
99%HPLC
Supply Ability
2000tons
Release date
2020-01-06
Career Henan Chemical Co
Product
1H-Isoindol-1-one,2,3-dihydro-4-methoxy-(9CI) 366453-22-7
Price
US $5.50/KG
Min. Order
1KG
Purity
98%min
Supply Ability
1kg-100kg
Release date
2020-01-10