ChemicalBook > CAS DataBase List > palitantin
palitantin
- Product Name
- palitantin
- CAS No.
- 15265-28-8
- Chemical Name
- palitantin
- Synonyms
- palitantin;(-)-Palitantine;(2R)-2β-(Hydroxymethyl)-3α-[(1E,3E)-1,3-heptadienyl]-5β,6β-dihydroxycyclohexanone;(2R,3S,5R,6R)-rel-3-(1E,3E)-1,3-Heptadienyl-5,6-dihydroxy-2-(hydroxymethyl)-cyclohexanone;Cyclohexanone, 3-(1E,3E)-1,3-heptadien-1-yl-5,6-dihydroxy-2-(hydroxymethyl)-, (2R,3S,5R,6R)-rel-
- CBNumber
- CB11305019
- Molecular Formula
- C14H22O4
- Formula Weight
- 254.32
- MOL File
- 15265-28-8.mol
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palitantin Property
- Melting point:
- 169℃ (ethyl acetate )
- alpha
- 235461 +4.4° (c = 0.8 in CHCl3)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- White solid.
- color
- White
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 25208
- Product name
- Palitantin
- Purity
- ≥95%
- Packaging
- 500μg
- Price
- $101
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 25208
- Product name
- Palitantin
- Purity
- ≥95%
- Packaging
- 2.5mg
- Price
- $354
- Updated
- 2024/03/01
Usbiological
- Product number
- 461969
- Product name
- Palitantin
- Packaging
- 1mg
- Price
- $355
- Updated
- 2021/12/16
Usbiological
- Product number
- 207318
- Product name
- Palitantin
- Packaging
- 1mg
- Price
- $379
- Updated
- 2021/12/16
Adipogen Life Sciences
- Product number
- AG-CN2-0140-M001
- Product name
- Palitantin
- Purity
- ≥95%(HPLC)
- Packaging
- 1mg
- Price
- $155
- Updated
- 2021/12/16
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palitantin Chemical Properties,Usage,Production
Description
Palitantin is a fungal metabolite originally isolated from P. palitans. It inhibits HIV-1 integrase with IC50 values of 350 and 268 μM for 3’-processing and strand transfer activity, respectively. Palitantin has been used as a standard for dereplication of natural products.
Uses
Palitantin is an antifungal and antiprotozoal compound.
IC 50
Leishmania; Fungal Metabolite
storage
+4°C
References
[1] J H BIRKINSHAW H R. Studies in the biochemistry of micro-organisms: Palitantin, C(14)H(22)O(4), a hitherto undescribed metabolic product of Penicillium palitans Westling.[J]. Biochemical Journal, 1936, 30 5: 801-808. DOI: 10.1042/bj0300801
[2] HUIXIAO HONG. Discovery of HIV-1 Integrase Inhibitors by Pharmacophore Searching?[J]. Journal of Medicinal Chemistry, 1997, 40 6: 930-936. DOI: 10.1021/jm960754h
[3] KRISTIAN F. NIELSEN*. Dereplication of Microbial Natural Products by LC-DAD-TOFMS[J]. Journal of Natural Products , 2011, 74 11: 2338-2348. DOI: 10.1021/np200254t
palitantin Preparation Products And Raw materials
Raw materials
Preparation Products
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