8-BROMOADENINE

Product Name: 8-BROMOADENINE
CAS No.: 6974-78-3
Chemical Name: 8-BROMOADENINE
Synonyms: AKOS NCG1-0087;8-BROMOADENINE;8-Brom-1H-adenin;8-bromo-1H-adenine;6-Amino-8-bromopurine;8-BroMo-7H-purin-6-aMine;8-bromo-9H-purin-6-amine;8-Bromo-1H-purin-6-amine;8-BROMOADENINE USP/EP/BP;6-Amino-8-bromo-9H-purine
CBNumber: CB1131491
Molecular Formula: C5H4BrN5
Formula Weight: 214.02
MOL File: 6974-78-3.mol

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8-BROMOADENINE Property

Melting point:: >250℃
Boiling point:: 287.4±50.0 °C(Predicted)
Density: 2.54±0.1 g/cm3(Predicted)
RTECS: UO7410000
solubility: DMSO (Slightly, Heated, Sonicated), Methanol (Slightly)
form: Powder
pka: 6.28±0.20(Predicted)
color: White to Pale Brown

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Safety

Hazard Codes: Xn
Risk Statements: 22
HazardClass: IRRITANT

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: B679370
Product name: 8-Bromoadenine
Packaging: 0.5g
Price: $75
Updated: 2021/12/16

TRC

Product number: B679370
Product name: 8-Bromoadenine
Packaging: 5g
Price: $265
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0025426
Product name: 8-BROMOADENINE
Purity: 95.00%
Packaging: 0.5G
Price: $638
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB08273
Product name: 8-Bromoadenine
Packaging: 10g
Price: $700
Updated: 2021/12/16

Matrix Scientific

Product number: 063686
Product name: 8-Bromo-9H-purin-6-amine
Packaging: 5g
Price: $765
Updated: 2021/12/16

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8-BROMOADENINE Chemical Properties,Usage,Production

Uses

8-Bromoadenine injected into mice before exposure to irradiation increased the radiosensitivity of bone marrow hemopoietic stem cells.

Synthesis

66224-66-6

6974-78-3

Adenine (40 g) was used as starting material, which was placed in a flask and liquid bromine (107 mL) was slowly added under mechanical stirring. After addition, the reaction was continued with stirring for 3 hours at room temperature. Upon completion of the reaction, excess liquid bromine was removed by addition of sodium bisulfite solution. Subsequently, the reaction solution was adjusted to neutral with ammonia, at which time a white powdery solid precipitated. A filtration operation was carried out and the resulting solid was washed with ice water to give 8-bromoadenine as a pale yellow solid (54 g) in 85.7% yield.

References

[1] Patent: CN108503643, 2018, A. Location in patent: Paragraph 0023; 0036; 0037; 0038
[2] Patent: US2008/234297, 2008, A1. Location in patent: Page/Page column 33; 38
[3] Synthetic Communications, 2013, vol. 43, # 11, p. 1469 - 1476
[4] Journal of Medicinal Chemistry, 2009, vol. 52, # 19, p. 5974 - 5989
[5] Collection of Czechoslovak Chemical Communications, 2000, vol. 65, # 7, p. 1126 - 1144

8-BROMOADENINE Preparation Products And Raw materials

Raw materials

Preparation Products

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8-BROMOADENINE Suppliers

Canada 1 China 72 Germany 3 India 1 Russia 1 The Netherlands 1 United Kingdom 6 United States 7 Global 92

3B Pharmachem (Wuhan) International Co.,Ltd.

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ShangHai Angti Biotechnology Co., Ltd.

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Shanghai YuanYe Biotechnology Co., Ltd.

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Shanghai SuperLan Chemcial Technique Centre

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View Lastest Price from 8-BROMOADENINE manufacturers

R&D Scientific Inc.

Product: 8-Bromoadenine 6974-78-3
Price: US $2500.00/g
Min. Order: 1g
Purity: 98
Supply Ability: 500 Kg
Release date: 2024-04-11

6974-78-3, 8-BROMOADENINERelated Search:

2-BROMOADENINE,8-BROMOADENINE nicotinamide-8-bromoadenine dinucleotide 8-BROMOADENINE-9-BETA-D-RIBOFURANOSIDE,6-Amino-8-bromopurine riboside, 8-Bromoadenine-9-β-D-ribofuranoside 9-(3'-aza-4'-hexyl-1',2',3',4'-tetradeoxyhexopyranos-1'-yl)-8-bromoadenine

8-BROMO-9H-PURIN-6-YLAMINE

8-BROMOADENINE

AKOS NCG1-0087

6-Amino-8-bromo-9H-purine

8-Bromo-1H-purin-6-amine

8-Bromo-9H-purine-6-amine

8-bromo-9H-purin-6-amine

9H-purin-6-amine, 8-bromo-

1H-Purin-6-aMine, 8-broMo-

8-BroMo-7H-purin-6-aMine

(8-bromo-7H-purin-6-yl)amine

6-Amino-8-bromopurine

8-bromoadenine crystalline

8-bromo-1H-adenine

8-BROMOADENINE USP/EP/BP

8-Brom-1H-adenin

6974-78-3

Nucleotides and Nucleic Acids