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4-dehydrowithaferin A

Product Name
4-dehydrowithaferin A
CAS No.
6850-30-2
Chemical Name
4-dehydrowithaferin A
Synonyms
4-oxo Withaferin A;4-dehydrowithaferin A;Ergosta-2,24-dien-26-oic acid, 5,6-epoxy-22,27-dihydroxy-1,4-dioxo-, δ-lactone, (5β,6β,22R)-
CBNumber
CB11316574
Molecular Formula
C28H36O6
Formula Weight
468.58
MOL File
6850-30-2.mol
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4-dehydrowithaferin A Property

storage temp. 
Store at -20°C
solubility 
DMF: 5mg/mL; DMSO: 5mg/mL; DMSO:PBS (pH 7.2) (1:1): 0.5mg/mL
form 
A crystalline solid
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
28295
Product name
4-oxo Withaferin A
Packaging
1mg
Price
$87
Updated
2024/03/01
Cayman Chemical
Product number
28295
Product name
4-oxo Withaferin A
Packaging
5mg
Price
$304
Updated
2024/03/01
Cayman Chemical
Product number
28295
Product name
4-oxo Withaferin A
Packaging
10mg
Price
$478
Updated
2024/03/01
AK Scientific
Product number
1293CB
Product name
4-DehydrowithaferinA
Packaging
1mg
Price
$187
Updated
2021/12/16
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4-dehydrowithaferin A Chemical Properties,Usage,Production

Description

4-oxo Withaferin A is a derivative of the steroidal lactone withaferin A that has anticancer activity.1 It is cytotoxic to A2780 ovarian cancer cells and carboplatin-resistant A2780 (A2780/CP70) cells (IC50s = 7.3 and <1 μM, respectively) and is 4.4-fold selective for A2780 cells over non-cancerous ARPE19 cells.

References

1. Perestelo, N.R., Llanos, G.G., Reyes, C.P., et al. Expanding the chemical space of withaferin A by incorporating silicon to improve its clinical potential on human ovarian carcinoma cells J. Med. Chem. 62(9),4571-4585(2019).

4-dehydrowithaferin A Preparation Products And Raw materials

Raw materials

Preparation Products

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4-dehydrowithaferin A Suppliers

China 8 United States 2 Global 10
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81

6850-30-2, 4-dehydrowithaferin ARelated Search:


  • 4-dehydrowithaferin A
  • 4-oxo Withaferin A
  • Ergosta-2,24-dien-26-oic acid, 5,6-epoxy-22,27-dihydroxy-1,4-dioxo-, δ-lactone, (5β,6β,22R)-
  • 6850-30-2