ARECOLINE HYDROCHLORIDE
- Product Name
- ARECOLINE HYDROCHLORIDE
- CAS No.
- 61-94-9
- Chemical Name
- ARECOLINE HYDROCHLORIDE
- Synonyms
- RARECHEM AX KI 5022;ARECOLINE HYDROCHLORIDE;methyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate hydrochloride;nicotinicacid,1,2,5,6-tetrahydro-1-methyl-,methylester,hydrochloride;ethyl 1-methyl-1,2,5,6-tetrahydropyridine-3-carboxylate hydrochloride;methyl 1-methyl-1,2,5,6-tetrahydropyridine-3-carboxylate hydrochloride;3-pyridinecarboxylicacid,1,2,5,6-tetrahydro-1-methyl-,methylester,hydroc;3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-1-Methyl-, Methyl ester, hydrochloride
- CBNumber
- CB1132584
- Molecular Formula
- C8H14ClNO2
- Formula Weight
- 191.66
- MOL File
- 61-94-9.mol
ARECOLINE HYDROCHLORIDE Property
- Melting point:
- 157-158 °C(Solv: ethyl ether (60-29-7))
- form
- Solid
- CAS DataBase Reference
- 61-94-9
Safety
- Toxicity
- dni-mus-ipr 60 mg/kg IJEBA6 17,1141,79
N-Bromosuccinimide Price
- Product number
- M357195
- Product name
- methyl1-methyl-1,2,5,6-tetrahydropyridine-3-carboxylatehydrochloride
- Packaging
- 25mg
- Price
- $220
- Updated
- 2021/12/16
- Product number
- PXT0000013
- Product name
- ARECOLINE HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $499.3
- Updated
- 2021/12/16
- Product number
- 18487
- Product name
- ArecolineHCl
- Packaging
- 25mg
- Price
- $1500
- Updated
- 2021/12/16
ARECOLINE HYDROCHLORIDE Chemical Properties,Usage,Production
Uses
Arecoline hydrochloride, a naturally occurring psychoactive alkaloid, is a partial agonist of nicotinic and muscarinic acetylcholine receptor. Arecoline hydrochloride exhibits stimulation, alertness, anxiolysis and anti-parasitic effects. Arecoline hydrochloride also can induce oxidative stress[1][2][3][4].
Safety Profile
Poison by intraperitoneal andintravenous routes. Questionable carcinogen withexperimental carcinogenic data. Whenheated to decomposition it emits very toxic fumes of NOxand HCl.
References
[1] Thangjam GS, et, al. Regulation of oxidative-stress responsive genes by arecoline in human keratinocytes. J Periodontal Res. 2009 Oct;44(5):673-82. DOI:10.1111/j.1600-0765.2008.01176.x
[2] Liu YJ, et, al. The pharmacology, toxicology and potential applications of arecoline: a review. Pharm Biol. 2016 Nov;54(11):2753-2760. DOI:10.3109/13880209.2016.1160251
[3] Volgin AD, et, al. DARK Classics in Chemical Neuroscience: Arecoline. ACS Chem Neurosci. 2019 May 15;10(5):2176-2185. DOI:10.1021/acschemneuro.8b00711
[4] Kuo TM, et, al. Arecoline induces TNF-alpha production and Zonula Occludens-1 redistribution in mouse Sertoli TM4 cells. J Biomed Sci. 2014 Sep 9;21(1):93. DOI:10.1186/s12929-014-0093-z
ARECOLINE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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