ChemicalBook > CAS DataBase List > 2-methacryloyloxyethyl phosphorylcholine

2-methacryloyloxyethyl phosphorylcholine

Product Name
2-methacryloyloxyethyl phosphorylcholine
CAS No.
67881-98-5
Chemical Name
2-methacryloyloxyethyl phosphorylcholine
Synonyms
2-(Methacryloyloxy)ethyl 2-(Trimethylammonio)ethyl Phosphate;2-(Methacryloyloxy)ethyl;Creatinol O-phosphate Magnesium;Quaternary ammonium salt -51/MPC;2-methacryloyloxyethyl phosphorylcholine;2-Methacryloyloxyethyl Phosphatidylcholine;2-Methylacryloyloxyethyl phosphate choline;O-[[2-(Methacryloyloxy)ethoxy]phosphonyl]choline;O-[[2-[(2-Methylpropenoyl)oxy]ethoxy]phosphonyl]choline;2-(Methacryloyloxy)ethyl2-(Trimethylammonio)ethylPhosphate>
CBNumber
CB11331313
Molecular Formula
C11H22NO6P
Formula Weight
295.27
MOL File
67881-98-5.mol
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2-methacryloyloxyethyl phosphorylcholine Property

Melting point:
143-148°C
Density 
1.22-1.41 at 21.5-22.4℃
vapor pressure 
0-0Pa at 25℃
storage temp. 
2-8°C
form 
Powder
color 
White to Almost white
Water Solubility 
83-86vol% at 20℃ and pH5.9-6.8[vol%]
InChI
InChI=1S/C11H22NO6P/c1-10(2)11(13)16-8-9-18-19(14,15)17-7-6-12(3,4)5/h1,6-9H2,2-5H3
InChIKey
ZSZRUEAFVQITHH-UHFFFAOYSA-N
SMILES
O(CC[N+](C)(C)C)P([O-])(=O)OCCOC(=O)C(=C)C
LogP
-1.76 at 21℃
Surface tension
71.9-72.01mN/m at 1-1.09g/L and 20.1-22℃
CAS DataBase Reference
67881-98-5(CAS DataBase Reference)
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Safety

Safety Statements 
24/25
WGK Germany 
1
HS Code 
29239000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
730114
Product name
2-Methacryloyloxyethyl phosphorylcholine
Purity
contains ≤100 ppm MEHQ as inhibitor, 97%
Packaging
5g
Price
$154
Updated
2024/03/01
TCI Chemical
Product number
M2005
Product name
2-(Methacryloyloxy)ethyl 2-(Trimethylammonio)ethyl Phosphate
Purity
>96.0%(T)
Packaging
1g
Price
$47
Updated
2024/03/01
TCI Chemical
Product number
M2005
Product name
2-(Methacryloyloxy)ethyl 2-(Trimethylammonio)ethyl Phosphate
Purity
>96.0%(T)
Packaging
5g
Price
$160
Updated
2024/03/01
TCI Chemical
Product number
M2005
Product name
2-(Methacryloyloxy)ethyl 2-(Trimethylammonio)ethyl Phosphate
Packaging
25G
Price
$636
Updated
2024/03/01
TRC
Product number
M220425
Product name
2-MethacryloyloxyethylPhosphatidylcholine
Packaging
1g
Price
$75
Updated
2021/12/16
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2-methacryloyloxyethyl phosphorylcholine Chemical Properties,Usage,Production

Chemical Properties

White solid

Uses

MPC block copolymers with styrene are biocompatible in nature.

Application

Among biocompatible polymers, a polymer family containing 2-methacryloyloxyethyl phosphorylcholine (MPC) has attracted attention for fundamental studies and applications. MPC polymers are synthetic phospholipid polymers with zwitterionic phosphorylcholine (PC) head groups, which can form cell-membrane-like structures on various material surfaces. This special surface structure has a unique capacity to prevent nonspecific protein adsorption (NPA) and thus biofouling by the adsorption of biomolecules, cells, and other biological entities. This property is helpful in applications involving biological entities (e.g., proteins, other biomolecules, cells), biological samples (e.g., tears, saliva), contact with plasma and whole blood, and implantation in the body or other biological environments[1].

General Description

Methacryloyloxyethyl phosphorylcholine (MPC), containing a phosphorylcholine group in the side chain is a most suitable monomer to mimic the phospholipid polar groups contained with cell membranes. MPC block copolymers are biocompatible in nature; it shows desirable interaction with living tissues. It is hydroscopic in nature.

References

[1] Seetasang, Sasikarn and Yan Xu. “Recent progress and perspectives in applications of 2-methacryloyloxyethyl phosphorylcholine polymers in biodevices at small scales.” Journal of Materials Chemistry B 14 (2022): 2323–2337.

2-methacryloyloxyethyl phosphorylcholine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-methacryloyloxyethyl phosphorylcholine manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
2-methacryloyloxyethyl phosphorylcholine 67881-98-5
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-12-05
Hebei Yanxi Chemical Co., Ltd.
Product
2-Methacryloyloxyethyl phosphorylcholine 67881-98-5
Price
US $40.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10 tons
Release date
2023-09-19
Shaanxi Dideu Medichem Co. Ltd
Product
2-(Methacryloyloxy)ethyl 2-(TriMethylaMMonio)ethyl Phosphate 67881-98-5
Price
US $1.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 tons
Release date
2020-01-16

67881-98-5, 2-methacryloyloxyethyl phosphorylcholineRelated Search:

2-Bromobenzonitrile 6-Mercaptopurine Dimethyl phthalate ISOEUGENOL Acetylcholine phosphorylcholine ETHYLENE GLYCOL METHACRYLATE PHOSPHATE 2-methacryloyloxyethyl phosphorylcholine Phosphoric acid 2-(acryloyloxy)ethyl ester

  • 2-Methacryloyloxyethyl Phosphatidylcholine
  • 2-methacryloyloxyethyl phosphorylcholine
  • Creatinol O-phosphate Magnesium
  • 2-(Methacryloyloxy)ethyl 2-(Trimethylammonio)ethyl Phosphate
  • Phosphoric Acid 2-(Methacryloyloxy)ethyl 2-(Trimethylammonio)ethyl Ester
  • [2-[[2-(Methacryloyloxy)ethoxy]phosphonyloxy]ethyl]trimethylaminium
  • Methacrylic acid 2-[[[2-(trimethylaminio)ethoxy]phosphonyl]oxy]ethyl ester
  • O-[[2-(Methacryloyloxy)ethoxy]phosphonyl]choline
  • O-[[2-[(2-Methylpropenoyl)oxy]ethoxy]phosphonyl]choline
  • Phosphoric acid hydrogen 2-(trimethylaminio)ethyl 2-(methacryloyloxy)ethyl ester
  • 2-(2-Methylprop-2-enoyloxy)ethyl 2-trimethylazaniumylethyl phosphate
  • 2-(Methacryloyloxy)ethyl 2-(trimethylammonio)ethyl phosphate ,96%
  • Phosphoric Acid 2-(Methacryloyloxy)ethyl 2-(Trimethylammonio)ethyl Ester 2-Methacryloyloxyethyl Phosphorylcholine
  • 2-Methacryloyloxyethyl phosphorylcholine contains ≤100 ppM 4-Methylphenol as inhibitor
  • 2-(Methacryloyloxy)ethyl
  • 3,5,8-Trioxa-4-phosphaundec-10-en-1-aMiniuM,4-hydroxy-N,N,N,10-tetraMethyl-9-oxo-, inner salt, 4-oxide
  • 2-Methacryloyloxyethyl phosphorylcholine contains <=100 ppM MEHQ as inhibitor, 97%
  • 2-(Methacryloyloxy)ethyl2-(Trimethylammonio)ethylPhosphate&gt
  • 2-Methylacryloyloxyethyl phosphate choline
  • Quaternary ammonium salt -51/MPC
  • 2-Methacryloyloxyethyl phosphorylcholine( contains ≤100 ppm 4-Methoxyphenol as inhibitor)
  • 2-(Methacryloyloxyethyl)-2'-((trimethylammonium)ethyl)phosphate
  • 67881-98-5
  • C11H22NO6P
  • Ammonium Polyhalides, etc. (Quaternary)
  • Quaternary Ammonium Compounds
  • MPC