ChemicalBook > CAS DataBase List > 2-methacryloyloxyethyl phosphorylcholine
2-methacryloyloxyethyl phosphorylcholine
- Product Name
- 2-methacryloyloxyethyl phosphorylcholine
- CAS No.
- 67881-98-5
- Chemical Name
- 2-methacryloyloxyethyl phosphorylcholine
- Synonyms
- 2-(Methacryloyloxy)ethyl 2-(Trimethylammonio)ethyl Phosphate;2-(Methacryloyloxy)ethyl;Creatinol O-phosphate Magnesium;Quaternary ammonium salt -51/MPC;2-methacryloyloxyethyl phosphorylcholine;2-Methacryloyloxyethyl Phosphatidylcholine;2-Methylacryloyloxyethyl phosphate choline;2-Methacryloyloxyethyl phosphorylcholine 98%;O-[[2-(Methacryloyloxy)ethoxy]phosphonyl]choline;O-[[2-[(2-Methylpropenoyl)oxy]ethoxy]phosphonyl]choline
- CBNumber
- CB11331313
- Molecular Formula
- C11H22NO6P
- Formula Weight
- 295.27
- MOL File
- 67881-98-5.mol
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2-methacryloyloxyethyl phosphorylcholine Property
- Melting point:
- 143-148°C
- Density
- 1.22-1.41 at 21.5-22.4℃
- vapor pressure
- 0-0Pa at 25℃
- storage temp.
- 2-8°C
- form
- Powder
- color
- White to Almost white
- Water Solubility
- 83-86vol% at 20℃ and pH5.9-6.8[vol%]
- InChI
- InChI=1S/C11H22NO6P/c1-10(2)11(13)16-8-9-18-19(14,15)17-7-6-12(3,4)5/h1,6-9H2,2-5H3
- InChIKey
- ZSZRUEAFVQITHH-UHFFFAOYSA-N
- SMILES
- O(CC[N+](C)(C)C)P([O-])(=O)OCCOC(=O)C(=C)C
- LogP
- -1.76 at 21℃
- Surface tension
- 71.9-72.01mN/m at 1-1.09g/L and 20.1-22℃
- CAS DataBase Reference
- 67881-98-5(CAS DataBase Reference)
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Safety
- Safety Statements
- 24/25
- WGK Germany
- 1
- HS Code
- 29239000
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H317May cause an allergic skin reaction
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P272Contaminated work clothing should not be allowed out of the workplace.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 730114
- Product name
- 2-Methacryloyloxyethyl phosphorylcholine
- Purity
- contains ≤100 ppm MEHQ as inhibitor, 97%
- Packaging
- 5g
- Price
- $159
- Updated
- 2025/07/31
TCI Chemical
- Product number
- M2005
- Product name
- 2-(Methacryloyloxy)ethyl 2-(Trimethylammonio)ethyl Phosphate
- Purity
- >96.0%(T)
- Packaging
- 1g
- Price
- $47
- Updated
- 2025/07/31
TCI Chemical
- Product number
- M2005
- Product name
- 2-(Methacryloyloxy)ethyl 2-(Trimethylammonio)ethyl Phosphate
- Purity
- >96.0%(T)
- Packaging
- 5g
- Price
- $160
- Updated
- 2025/07/31
TCI Chemical
- Product number
- M2005
- Product name
- 2-(Methacryloyloxy)ethyl 2-(Trimethylammonio)ethyl Phosphate
- Packaging
- 25G
- Price
- $636
- Updated
- 2025/07/31
TRC
- Product number
- M220425
- Product name
- 2-MethacryloyloxyethylPhosphatidylcholine
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
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2-methacryloyloxyethyl phosphorylcholine Chemical Properties,Usage,Production
Chemical Properties
White solid
Uses
MPC block copolymers with styrene are biocompatible in nature.
Application
Among biocompatible polymers, a polymer family containing 2-methacryloyloxyethyl phosphorylcholine (MPC) has attracted attention for fundamental studies and applications. MPC polymers are synthetic phospholipid polymers with zwitterionic phosphorylcholine (PC) head groups, which can form cell-membrane-like structures on various material surfaces. This special surface structure has a unique capacity to prevent nonspecific protein adsorption (NPA) and thus biofouling by the adsorption of biomolecules, cells, and other biological entities. This property is helpful in applications involving biological entities (e.g., proteins, other biomolecules, cells), biological samples (e.g., tears, saliva), contact with plasma and whole blood, and implantation in the body or other biological environments[1].
General Description
2-methacryloyloxyethyl phosphorylcholine(MPC), containing a phosphorylcholine group in the side chain is a most suitable monomer to mimic the phospholipid polar groups contained with cell membranes. MPC block copolymers are biocompatible in nature; it shows desirable interaction with living tissues. It is hydroscopic in nature.
in vivo
2-Methacryloyloxyethyl phosphorylcholine polymer (PMB-coated suture; s.c.) suppresses bacterial attachment and biofilm formation in C57BL/6J mice[4].
References
[1] Seetasang, Sasikarn and Yan Xu. “Recent progress and perspectives in applications of 2-methacryloyloxyethyl phosphorylcholine polymers in biodevices at small scales.” Journal of Materials Chemistry B 14 (2022): 2323–2337.
2-methacryloyloxyethyl phosphorylcholine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-methacryloyloxyethyl phosphorylcholine manufacturers
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
- Product
- 2-Methacryloyloxyethyl phosphorylcholine 67881-98-5
- Price
- US $2.00-5.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-07-18
Hebei Chuanghai Biotechnology Co., Ltd
- Product
- 2-methacryloyloxyethyl phosphorylcholine 67881-98-5
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-12-05
Hebei Yanxi Chemical Co., Ltd.
- Product
- 2-Methacryloyloxyethyl phosphorylcholine 67881-98-5
- Price
- US $40.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 10 tons
- Release date
- 2023-09-19
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