saintopin
- Product Name
- saintopin
- CAS No.
- 131190-63-1
- Chemical Name
- saintopin
- Synonyms
- saintopin;1,3,8,10,11-Pentahydroxynaphthacene-5,12-dione
- CBNumber
- CB11347691
- Molecular Formula
- C18H10O7
- Formula Weight
- 0
- MOL File
- 131190-63-1.mol
N-Bromosuccinimide Price
- Product number
- INB0003914
- Product name
- SAINTOPIN
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496.77
- Updated
- 2021/12/16
saintopin Chemical Properties,Usage,Production
Uses
Saintopin is an antitumor antibiotic. Saintopin is also an inhibitor of DNA topoisomerases I and II. Saintopin induces DNA cleavage[1][2].
Definition
ChEBI: A member of the class of tetracenequinones that is tetracene-5,12-dione in which the hydrogens at positions 1, 3, 8, 10, and 11 have been replaced by hydroxy groups. Isolated from Paecilomyces.
IC 50
Topoisomerase I; Topoisomerase II
References
[1] Yamashita Y, et al. Saintopin, a new antitumor antibiotic with topoisomerase II dependent DNA cleavage activity, from Paecilomyces. J Antibiot (Tokyo). 1990 Oct;43(10):1344-6. DOI:10.7164/antibiotics.43.1344
[2] eteurtre F, et al. Saintopin, a dual inhibitor of DNA topoisomerases I and II, as a probe for drug-enzyme interactions. J Biol Chem. 1994 Nov 18;269(46):28702-7. PMID:7961822
saintopin Preparation Products And Raw materials
Raw materials
Preparation Products
saintopin Suppliers
- Tel
- 15002134094
- marketing@targetmol.cn
- Country
- China
- ProdList
- 29423
- Advantage
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