nucleocidin
- Product Name
- nucleocidin
- CAS No.
- 24751-69-7
- Chemical Name
- nucleocidin
- Synonyms
- T-3018;NSC 521007;nucleocidin;Antibiotic T-3018;LTBCQBSAWAZBDF-XPQPFPQWSA-N;4'-Fluoro-5'-O-sulfamoyladenosine;5'-O-Sulfamoyl-4'-fluoroadenosine;Adenosine, 4'-C-fluoro-, 5'-sulfamate;Sulfamic acid 4'-fluoro-5'-adenosyl ester
- CBNumber
- CB11360153
- Molecular Formula
- C10H13FN6O6S
- Formula Weight
- 364.31
- MOL File
- 24751-69-7.mol
nucleocidin Property
- Melting point:
- >190° (dec)
- Boiling point:
- 747.6±70.0 °C(Predicted)
- Density
- 2.23±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 9.15±0.70(Predicted)
Safety
- Toxicity
- LD50 i.p. in mice: ~0.2 mg/kg (Thomas)
N-Bromosuccinimide Price
- Product number
- N925200
- Product name
- Nucleocidin
- Packaging
- 25mg
- Price
- $7975
- Updated
- 2021/12/16
- Product number
- 60808
- Product name
- Nucleocidin
- Packaging
- 25mg
- Price
- $8250
- Updated
- 2021/12/16
- Product number
- 60808
- Product name
- Nucleocidin
- Packaging
- 50mg
- Price
- $9750
- Updated
- 2021/12/16
- Product number
- NUC0005689
- Product name
- NUCLEOCIDIN
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $501.99
- Updated
- 2021/12/16
- Product number
- 60808
- Product name
- Nucleocidin
- Packaging
- 10mg
- Price
- $6750
- Updated
- 2021/12/16
nucleocidin Chemical Properties,Usage,Production
Uses
Nucleocidin is used in studies relating to novel parasite inhibitors.
Definition
ChEBI: Nucleocidin is a nucleoside antibiotic that is 5'-O-sulfamoyladenosine in which the hydrogen atom at position 4' is replaced by a fluorine atom. It is a natural product synthesized by several Streptomyces species. It exhibits broad spectrum antibacterial activity, and also has a strong effect against Trypanosoma brucei, the protozoan parasite responsible for the African sleeping sickness. It has a role as a bacterial metabolite, an antibacterial agent, a trypanocidal drug, a protein synthesis inhibitor and a nucleoside antibiotic. It is a member of adenosines, an organofluorine compound, a sulfamate ester, a member of 6-aminopurines and a diol. It is functionally related to an adenosine.