spantide II

Product Name: spantide II
CAS No.: 129176-97-2
Chemical Name: spantide II
Synonyms: (D-Lys(nicotinoyl)1,β-(3-pyridyl)-Ala3;(D-Lys(nicotinoyl)1,β-(3-pyridyl)-Ala3,3,4-dichloro-D-Phe5,Asn6,D-Trp7·9,Nle11)-Substance P;(D-Lys(nicotinoyl)1,b-(3-pyridyl)-Ala3,3,4-dichloro-D-Phe5,Asn6,D-Trp7·9,Nle11)-Substance P;H-D-Lys(nicotinoyl)-Pro-b-(3-pyridyl)-Ala-Pro-3,4-dichloro-D-Phe-Asn-D-Trp-Phe-D-Trp-Leu-Nle-NH2;(D-Lys(nicotinoyl)?,β-(3-pyridyl)-Ala?,3,4-dichloro-D-Phe?,Asn?,D-Trp?·?,Nle??)-Substance P trifluoroacetate salt;(D-Lys(nicotinoyl)1,β-(3-pyridyl)-Ala3,3,4-dichloro-D-Phe?,Asn?,D-Trp?·?,Nle11)-Substance P trifluoroacetate salt;(D-Lys(nicotinoyl)1,b-(3-pyridyl)-Ala3,3,4-dichloro-D-Phe5,Asn6,D-Trp7·9, Nle 11)-Substance P trifluoroacetate salt;L-Norleucinamide, N6-(3-pyridinylcarbonyl)-D-lysyl-L-prolyl-3-(3-pyridinyl)-L-alanyl-L-prolyl-3,4-dichloro-D-phenylalanyl-L-asparaginyl-D-tryptophyl-L-phenylalanyl-D-tryptophyl-L-leucyl-
CBNumber: CB11360274
Molecular Formula: C86H104Cl2N18O13
Formula Weight: 1668.79
MOL File: 129176-97-2.mol

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spantide II Property

form: Lyophilized solid.
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: BRS0000754
Product name: SPANTIDE II
Purity: 95.00%
Packaging: 0.5MG
Price: $475
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: BRS0000754
Product name: SPANTIDE II
Purity: 95.00%
Packaging: 1MG
Price: $550
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: BRS0000754
Product name: SPANTIDE II
Purity: 95.00%
Packaging: 5MG
Price: $1000
Updated: 2021/12/16

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spantide II Chemical Properties,Usage,Production

Uses

Spantide II, an undecapeptide substance P (SP) analog, is a potent neurokinin-1 receptor (NK-1R) antagonist. Spantide II binds with NK-1R and blocks proinflammatory activities associated with SP. Spantide II can be used in the research of inflammatory skin disorders, such as psoriasis and contact dermatitis[1][2][3].

IC 50

NK1

References

[1] Xu XJ, et al. Spantide II, a novel tachykinin antagonist, and galanin inhibit plasma extravasation induced by antidromic C-fiber stimulation in rat hindpaw. Neuroscience. 1991;42(3):731-7. DOI:10.1016/0306-4522(91)90041-l
[2] Kikwai L, et al. In vitro and in vivo evaluation of topical formulations of spantide II. AAPS PharmSciTech. 2005 Oct 31;6(4):E565-72. DOI:10.1208/pt060471
[3] Babu RJ, et al. Percutaneous absorption and anti-inflammatory effect of a substance P receptor antagonist: spantide II. Pharm Res. 2004 Jan;21(1):108-13. DOI:10.1023/b:pham.0000012157.80716.73

spantide II Preparation Products And Raw materials

Raw materials

Preparation Products

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spantide II Suppliers

China 29 South Korea 1 United States 1 Global 31

Shanghai Hanhong Scientific Co.,Ltd.

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Chemsky (shanghai) International Co.,Ltd

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BOC Sciences

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Nanjing Leon Biological Technology Co., Ltd.

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Nanjing Peptide Biotech Ltd.

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Nanjing Meihao Pharmaceutical Technology Co., Ltd.

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Nanjing TGpeptide Biotechnology Co.,Ltd.

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Hangzhou Go Top Peptide Biotech

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129176-97-2, spantide IIRelated Search:

Betahistine dihydrochloride 2,6-DICHLOROPHENETHYLAMINE H-DL-TRP-NH2 HCL Triethylenetetramine Dihydrochloride 2-(2-Methoxyphenoxy)ethylamine (R)-(+)-1,2-Diaminopropane dihydrochloride 1-METHYL-2-PYRIDIN-2-YL-ETHYLAMINE METHYL-(1-METHYL-2-PYRIDIN-2-YL-ETHYL)-AMINE 2-METHYLAMINO-1-PYRROLIDIN-1-YL-ETHANONE X HCL >98% 3-(2-PYRIDINYL)PROPYLAMINE H-LEU-ALA-NH2 HCL 2-chloroamphetamine H-ASN-NH2 HCL 4-AMINOBUTYRAMIDE, HYDROCHLORIDE H-D-PHE-NH2 HCL H-GLY-LEU-NH2 HCL N-ethylpyridine-2-ethylamine N-(PYRIDIN-3-YLMETHYL)BUTAN-1-AMINE

(D-Lys(nicotinoyl)1,b-(3-pyridyl)-Ala3,3,4-dichloro-D-Phe5,Asn6,D-Trp7·9,Nle11)-Substance P

H-D-Lys(nicotinoyl)-Pro-b-(3-pyridyl)-Ala-Pro-3,4-dichloro-D-Phe-Asn-D-Trp-Phe-D-Trp-Leu-Nle-NH2

L-Norleucinamide, N6-(3-pyridinylcarbonyl)-D-lysyl-L-prolyl-3-(3-pyridinyl)-L-alanyl-L-prolyl-3,4-dichloro-D-phenylalanyl-L-asparaginyl-D-tryptophyl-L-phenylalanyl-D-tryptophyl-L-leucyl-

(D-Lys(nicotinoyl)1,β-(3-pyridyl)-Ala3,3,4-dichloro-D-Phe5,Asn6,D-Trp7·9,Nle11)-Substance P

(D-Lys(nicotinoyl)1,β-(3-pyridyl)-Ala3,3,4-dichloro-D-Phe?,Asn?,D-Trp?·?,Nle11)-Substance P trifluoroacetate salt

(D-Lys(nicotinoyl)?,β-(3-pyridyl)-Ala?,3,4-dichloro-D-Phe?,Asn?,D-Trp?·?,Nle??)-Substance P trifluoroacetate salt

(D-Lys(nicotinoyl)1,b-(3-pyridyl)-Ala3,3,4-dichloro-D-Phe5,Asn6,D-Trp7·9, Nle 11)-Substance P trifluoroacetate salt

(D-Lys(nicotinoyl)1,β-(3-pyridyl)-Ala3

129176-97-2

C86H104Cl2N18O13