eleutherin

Product Name: eleutherin
CAS No.: 478-36-4
Chemical Name: eleutherin
Synonyms: eleutherin;(+)-eleutherin;(1R,3S)-9-Methoxy-1,3-dimethyl-3,4-dihydro-1H-benzo[g]isochromene-5,10-dione;1H-Naphtho[2,3-c]pyran-5,10-dione, 3,4-dihydro-9-methoxy-1,3-dimethyl-, (1R,3S)-;(1R,3S)-9-methoxy-1,3-dimethyl-3,4,5,10-tetrahydro-1H-naphtho[2,3-c]pyran-5,10-dione
CBNumber: CB11367945
Molecular Formula: C16H16O4
Formula Weight: 272.3
MOL File: 478-36-4.mol

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eleutherin Property

Melting point:: 175 °C
Boiling point:: 465.3±45.0 °C(Predicted)
Density: 1.25±0.1 g/cm3(Predicted)
form: Solid
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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eleutherin Chemical Properties,Usage,Production

Chemical Properties

Yellow crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from shallots.

Uses

Eleutherin is a type of naphthoquinone derivative with the protective effect against the injury ofhuman umbilical vein endothelial cells (HUVECs), which can be isolated from the edible bulbs of Eleutherine americana (Hong-Cong)[1].

Definition

ChEBI: Eleutherin is a benzoisochromanequinone and a member of p-quinones.

References

[1] Chen D, et al. New naphtoquinones derivatives from the edible bulbs of Eleutherine americana and their protective effect on the injury of human umbilical vein endothelial cells. Fitoterapia. 2019 Jan;132:46-52. DOI:10.1016/j.fitote.2018.11.009
[2] Castro ALG, et, al. Evaluation of the genotoxicity and mutagenicity of isoeleutherin and eleutherin isolated from Eleutherine plicata herb. using bioassays and in silico approaches. Arabian Journal of Chemistry. Volume 14, Issue 4, April 2021, 103084.
[3] Krishnan P, et, al. Novel mechanisms of DNA topoisomerase II inhibition by pyranonaphthoquinone derivatives-eleutherin, alpha lapachone, and beta lapachone. Biochem Pharmacol. 2000 Nov 1;60(9):1367-79. DOI:10.1016/s0006-2952(00)00437-8

eleutherin Preparation Products And Raw materials

Raw materials

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eleutherin Suppliers

China 32 United States 1 Global 33

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478-36-4, eleutherinRelated Search:

eleutherin

(1R,3S)-9-methoxy-1,3-dimethyl-3,4,5,10-tetrahydro-1H-naphtho[2,3-c]pyran-5,10-dione

1H-Naphtho[2,3-c]pyran-5,10-dione, 3,4-dihydro-9-methoxy-1,3-dimethyl-, (1R,3S)-

(+)-eleutherin

(1R,3S)-9-Methoxy-1,3-dimethyl-3,4-dihydro-1H-benzo[g]isochromene-5,10-dione

478-36-4