ChemicalBook > CAS DataBase List > vanoxonin
vanoxonin
- Product Name
- vanoxonin
- CAS No.
- 86933-99-5
- Chemical Name
- vanoxonin
- Synonyms
- vanoxonin;MG-245-CF2-A;Antibitic MG-245CF2A;Antibiotic MG 245CF2A;(+)-N-(2,3-Dihydroxybenzoyl)-L-Thr-N5-Ac-N5-hydroxy-L-Orn-OH;N-(2,3-dihydroxybenzoyl)-L-threonyl-N5-acetyl-N5-hydroxy-L-ornithine;N5-Acetyl-N2-[N-(2,3-dihydroxybenzoyl)-L-threonyl]-N5-hydroxy-L-ornithine
- CBNumber
- CB11370969
- Molecular Formula
- C18H25N3O9
- Formula Weight
- 427.408
- MOL File
- 86933-99-5.mol
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vanoxonin Property
- storage temp.
- -20°C
- form
- A solid
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- INB0004203
- Product name
- VANOXONIN
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $495.11
- Updated
- 2021/12/16
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vanoxonin Chemical Properties,Usage,Production
Biological Activity
Vanoxonin is a bacterial metabolite that has been found in S. hirsuta.1 It forms a complex with vanadium, and the complex inhibits thymidylate synthetase with an IC50 value of 0.7 μg/ml. The vanoxonin-vanadium complex is cytotoxic to L1210 leukemia cells (MIC = 25 μg/ml) and increases survival in Ehrlich murine spontaneous adenocarcinoma and L1210 mouse tumor models.
References
1.Kanai, F., Sawa, T., Hamada, M., et al.Vanoxonin, a new inhibitor of thymidylate synthetaseJ. Antibiot. (Tokyo)36(6)656-660(1983)
vanoxonin Preparation Products And Raw materials
Raw materials
Preparation Products
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