Capromab Pendetide

Product Name: Capromab Pendetide
CAS No.: 145464-28-4
Chemical Name: Capromab Pendetide
Synonyms: Prostascint;Cytogen 356;Capromab Pendetide;Oncoscint prostate;Research Grade Capromab;Research Grade Capromab (DHG01303);Immunoglobulin G 1 (mouse monoclonal 7E11-C5.3 anti-human prostatic carcinoma cell), disulfide with mouse monoclonal 7E11-C5.3 light chain, dimer, N(sup 6)-(N-(2-((2-(bis(carboxymethyl)amino)ethyl)(carboxymethyl)amino)ethyl)-N-(carboxymethyl)glycyl)-N(sup 2)-(N-glycyl-L-tyrosyl)-L-lysine conjugate
CBNumber: CB11379720
Molecular Formula: C10H15N5O11P2
Formula Weight: 443.200522
MOL File: 145464-28-4.mol

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Hazard and Precautionary Statements (GHS)

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Capromab Pendetide Chemical Properties,Usage,Production

Uses

Monoclonal antibody.

General Description

Capromab (ProstaScint Kit for the preparation of In-111capromab pendetide, murine) is an MAb (murine IgG1 κ)that derives from an initial sensitization with a glycoproteinexpressed by prostate epithelium known as prostate surfacemembrane antigen (PSMA). The MAb recognizes PSMAspecifically and thus is specific for prostate adenocarcinomas.The drug is used in newly diagnosed patients withproven prostate cancer who are at high risk for pelvic lymphmetastasis. PSMA has been found in many primary andmetastatic prostate cancer lesions. The cytoplasmic domainmarker 7E11-C5.3 reacts with more than 95% of adenocarcinomasevaluated.
To join the indium-111 to the antibody, a linker-chelatoris used. This moiety is glycyltyrosyl-(N-ethylenetriaminepentaaceticacid)-lysine HCl.

Capromab Pendetide Preparation Products And Raw materials

Raw materials

Preparation Products

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Capromab Pendetide Suppliers

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145464-28-4, Capromab PendetideRelated Search:

Immunoglobulin G2/G4, anti-(human complement C5) (human-Mus musculus ALXN1210 heavy chain), disulfide with human-Mus musculus ALXN1210 κ-chain, dimer Vonlerolizumab Frexalimab Suvratoxumab Flotetuzumab Zelminemab Voxalatamab EV2-7 Tavolimab Firivumab

Capromab Pendetide

Cytogen 356

Immunoglobulin G 1 (mouse monoclonal 7E11-C5.3 anti-human prostatic carcinoma cell), disulfide with mouse monoclonal 7E11-C5.3 light chain, dimer, N(sup 6)-(N-(2-((2-(bis(carboxymethyl)amino)ethyl)(carboxymethyl)amino)ethyl)-N-(carboxymethyl)glycyl)-N(sup 2)-(N-glycyl-L-tyrosyl)-L-lysine conjugate

Oncoscint prostate

Prostascint

Research Grade Capromab (DHG01303)

Research Grade Capromab

145464-28-4