ChemicalBook > CAS DataBase List > BGP 15

BGP 15

Product Name
BGP 15
CAS No.
951628-79-8
Chemical Name
BGP 15
Synonyms
BGP 15
CBNumber
CB11399766
Molecular Formula
C14H23ClN4O2
Formula Weight
314.81
MOL File
951628-79-8.mol
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BGP 15 Property

Melting point:
>177°C (dec.)
storage temp. 
-20°C
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
Pale Yellow to Pale Beige
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Safety

Hazard Codes 
Xn
Risk Statements 
22
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
B4813
Product name
BGP-15
Purity
≥98% (HPLC)
Packaging
5MG
Price
$170
Updated
2023/06/20
Sigma-Aldrich
Product number
B4813
Product name
BGP-15
Purity
≥98% (HPLC)
Packaging
25MG
Price
$682
Updated
2023/06/20
Tocris
Product number
6703
Product name
BGP15
Purity
≥98%(HPLC)
Packaging
5
Price
$115
Updated
2021/12/16
Tocris
Product number
6703
Product name
BGP15
Purity
≥98%(HPLC)
Packaging
25
Price
$449
Updated
2021/12/16
Biorbyt Ltd
Product number
orb545890
Product name
bGP-15
Purity
>98%
Packaging
5mg
Price
$226.1
Updated
2021/12/16
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BGP 15 Chemical Properties,Usage,Production

Uses

BGP-15 has been used to study its influence on proteasomal degradation of missense dystrophins.

Uses

BGP 15 is a calcipotriene-based vitamin D3 analog that inhibits poly(ADP-ribose) polymerasesis (PARP), a class of enzymes that regulate DNA repair and apoptosis (1). BGP 15 is also a cardioprotective agent (2). Also, BPG 15 improves mitochondrial function, protects neurons from dying in vitro and in vivo, and promotes cardiac innervation in vivo.

General Description

BGP-15 is a hydroxylamine derivative, which has cytoprotective and neuroprotective properties. It reduces phospho- c-Jun N-terminal kinase (pJNK) and p38 stress signalling. BGP-15 also stimulates non-specific serine/threonine protein kinase (AKT) and insulin-like growth factor 1 receptor (IGFR1) protective signalling. BGP-15 functions as an insulin sensitizer in an olanzapine-induced metabolic disorder. It protects cells against cell death and enhances the expression of heat shock protein (HSP). BGP-15 might be used to treat heart failure (HF) and atrial fibrillation (AF).

Biochem/physiol Actions

BGP-15 is PARP inhibitor, HSP72 activator.

BGP 15 Preparation Products And Raw materials

Raw materials

Preparation Products

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BGP 15 Suppliers

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