1-BENZYL-3,3-DIMETHYL-PIPERIDIN-4-ONE
- Product Name
- 1-BENZYL-3,3-DIMETHYL-PIPERIDIN-4-ONE
- CAS No.
- 173186-91-9
- Chemical Name
- 1-BENZYL-3,3-DIMETHYL-PIPERIDIN-4-ONE
- Synonyms
- N-Benzyl-3,3-dimethyl-4-piperidone;1-Benzyl-3,3-dimethyl-4-piperidone;N-benzyl-3,3-dimethylpiperidin-4-one;1-BENZYL-3,3-DIMETHYL-PIPERIDIN-4-ONE;3,3-dimethyl-1-(phenylmethyl)-4-piperidinone;4-Piperidinone, 3,3-dimethyl-1-(phenylmethyl)-;1-BENZYL-3,3-DIMETHYL-PIPERIDIN-4-ONE ISO 9001：2015 REACH
- CBNumber
- CB11502445
- Molecular Formula
- C14H19NO
- Formula Weight
- 217.31
- MOL File
- 173186-91-9.mol
1-BENZYL-3,3-DIMETHYL-PIPERIDIN-4-ONE Property
- Boiling point:
- 318.0±22.0 °C(Predicted)
- Density
- 1.031±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 7.14±0.40(Predicted)
- Appearance
- White to yellow Solid-Liquid Mixture
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B300093
- Product name
- 1-Benzyl-3,3-dimethylpiperidin-4-one
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- B300093
- Product name
- 1-Benzyl-3,3-dimethylpiperidin-4-one
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 8930AA
- Product name
- 1-Benzyl-3,3-dimethylpiperidin-4-one
- Packaging
- 1g
- Price
- $117
- Updated
- 2021/12/16
- Product number
- 4H56-1-205
- Product name
- 1-Benzyl-3,3-dimethylpiperidin-4-one
- Packaging
- 1g
- Price
- $125
- Updated
- 2021/12/16
- Product number
- 4H56-1-205
- Product name
- 1-Benzyl-3,3-dimethylpiperidin-4-one
- Packaging
- 5G
- Price
- $450
- Updated
- 2021/12/16
1-BENZYL-3,3-DIMETHYL-PIPERIDIN-4-ONE Chemical Properties,Usage,Production
Synthesis
324769-02-0
173186-91-9
Oxidation Procedure: 0.40 mL (5.6 mmol) of dimethyl sulfoxide was dissolved in 5 mL of dichloromethane and cooled to -78 °C. 0.35 mL (2.48 mmol) of trifluoroacetic anhydride was slowly added dropwise under stirring and stirring was continued for 30 minutes. Subsequently, 0.25 g (1.14 mmol) of a 2 mL solution of 1-benzyl-3,3-dimethyl-4-hydroxypiperidine in dichloromethane was added dropwise, and the reaction mixture was stirred at -78 °C for 1 hour. Then, 1.0 mL (7.2 mmol) of triethylamine was added and the reaction mixture was slowly warmed to 0°C and stirred at this temperature for 2 hours. After completion of the reaction, the mixture was poured into water and extracted with ethyl acetate. The organic phases were combined, dried over anhydrous sodium sulfate and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography with the eluent being a hexane solution of 0-20% ethyl acetate. The fraction containing the target product was collected and concentrated under reduced pressure to give 0.20 g (79% yield) of 3,3-dimethyl-1-phenylmethyl-piperidin-4-one.
References
[1] Patent: EP1204659, 2003, B1. Location in patent: Page/Page column 26
[2] Patent: EP1204660, 2004, B1. Location in patent: Page 15
1-BENZYL-3,3-DIMETHYL-PIPERIDIN-4-ONE Preparation Products And Raw materials
Raw materials
Preparation Products
1-BENZYL-3,3-DIMETHYL-PIPERIDIN-4-ONE Suppliers
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View Lastest Price from 1-BENZYL-3,3-DIMETHYL-PIPERIDIN-4-ONE manufacturers
- Product
- 1-BENZYL-3,3-DIMETHYL-PIPERIDIN-4-ONE 173186-91-9
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2019-07-09