6-HYDROXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE

Product Name: 6-HYDROXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE
CAS No.: 22245-98-3
Chemical Name: 6-HYDROXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE
Synonyms: 6-HYDROXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE;3,4-Dihydro-6-hydroxy-1(2H)-isoquinolinone;3,4-Dihydro-6-hydroxyisoquinolin-1(2H)-one;1(2H)-Isoquinolinone,3,4-dihydro-6-hydroxy-;6-Hydroxy-2- Oxo-1,2,3,4-Tetrahydroquinolene;6-hydroxy-1,2,3,4-tetrahydroisoquinolin-1-one;6-Hydroxy-3,4-dihydro-1-oxo-2(1H)-isoquinoline;6-Hydroxy-3,4-dihydro-1(2H)-isoquinolinone ,97%
CBNumber: CB11508164
Molecular Formula: C9H9NO2
Formula Weight: 163.17
MOL File: 22245-98-3.mol

More

Less

6-HYDROXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE Property

storage temp.: Storage temp. 2-8°C
Appearance: White to off-white Solid

More

Less

Safety

HS Code: 29334900

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

More

Less

N-Bromosuccinimide Price

TRC

Product number: H947918
Product name: 6-Hydroxy-3,4-dihydro-2h-isoquinolin-1-one
Packaging: 100mg
Price: $95
Updated: 2021/12/16

Matrix Scientific

Product number: 118890
Product name: 6-Hydroxy-3,4-dihydroisoquinolin-1(2H)-one
Purity: 95+%
Packaging: 500mg
Price: $101
Updated: 2021/12/16

Ark Pharm

Product number: P000537185
Product name: 6-Hydroxy-3,4-dihydroisoquinolin-1(2H)-one
Purity: 98%
Packaging: 1g
Price: $104
Updated: 2021/12/16

Ark Pharm

Product number: P000537185
Product name: 6-Hydroxy-3,4-dihydroisoquinolin-1(2H)-one
Purity: 98%
Packaging: 100mg
Price: $27
Updated: 2021/12/16

Ark Pharm

Product number: P000537185
Product name: 6-Hydroxy-3,4-dihydroisoquinolin-1(2H)-one
Purity: 98%
Packaging: 250mg
Price: $38
Updated: 2021/12/16

More

Less

6-HYDROXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE Chemical Properties,Usage,Production

Synthesis

22246-12-4

22245-98-3

Step 1: 6-Methoxy-3,4-dihydroisoquinolin-1(2H)-one (2.58 g, 14 mmol) was dissolved in dichloromethane at -78 °C and boron tribromide (2.7 mL, 28 mmol) was slowly added. The reaction mixture was gradually warmed to room temperature and stirred overnight. Upon completion of the reaction, the reaction was quenched with cold water and subsequently extracted with ethyl acetate. The organic phases were combined and concentrated in vacuum to remove the solvent. The crude product was purified by ISCO CombiFlash? system using silica gel column chromatography with a dichloromethane solution of 0-15% methanol as eluent to afford 6-hydroxy-3,4-dihydroisoquinolin-1-one as a light brown solid (1.8 g, 75% yield) with a melting point of 204-206 °C; mass spectrum (electrospray ionization) m/z 162.1 [M+H ]+.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 2, p. 814 - 819
[2] Patent: US2009/69300, 2009, A1. Location in patent: Page/Page column 23
[3] Journal of Medicinal Chemistry, 2012, vol. 55, # 5, p. 2452 - 2468
[4] Patent: US2003/225122, 2003, A1. Location in patent: Page 18-19
[5] Bioorganic and Medicinal Chemistry Letters, 2008, vol. 18, # 16, p. 4727 - 4730

6-HYDROXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

6-HYDROXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE Suppliers

China 56 India 4 Ukraine 1 United Kingdom 1 United States 8 Global 70

China DongFan Chemical Co.,LTD

Tel: 86-0571-85151182
Fax: 86-0571-85151182
Country: China
ProdList: 5691
Advantage: 66

Shanghai Synthfine Chemical Co.,Ltd

Tel: 15921303235
Fax: QQ489466966
Email: sales@synthfine.com
Country: China
ProdList: 1041
Advantage: 58

Shanghai Xiannuo Biotechnology Co., Ltd.

Tel: 021-50718719 13918719472
Fax: 021-50718719
Country: China
ProdList: 979
Advantage: 58

Nanjing Norris-Pharm Technology Co., Ltd

Tel: 18652989687
Fax: +86-25-52131256
Email: sales@norris-pharm.com
Country: China
ProdList: 8878
Advantage: 55

Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.

Tel: +86-28-85122536 85324413
Fax: +86-28-85326443
Email: market@astatech.cn
Country: China
ProdList: 8026
Advantage: 55

Ketenechem (Shanghai) Co,. Ltd.

Tel: 021-61315236
Fax: 021-58958628
Email: sales@ketenechem.com
Country: China
ProdList: 49
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

NINGBO INNO PHARMCHEM CO.,LTD.

Tel: 86-574-27787657
Fax: 86-574-27912196
Email: info@dearchem.com
Country: China
ProdList: 4613
Advantage: 58

ShangHai AmK Pharmaceutical Technology Co., Ltd.

Tel: 微信 17321281695 18019252918
Fax: 17321281695
Email: sale@amkchem.com
Country: China
ProdList: 15136
Advantage: 55

Shanghai HuanChuan Industry Co.,Ltd.

Tel: 021-61478794
Fax: 021-61478794
Email: sales@hcshhai.com
Country: China
ProdList: 9793
Advantage: 50

More

Less

View Lastest Price from 6-HYDROXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 6-HYDROXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE 22245-98-3
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-02-19

Career Henan Chemical Co

Product: 6-HYDROXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE 22245-98-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2020-01-14

22245-98-3, 6-HYDROXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONERelated Search:

narciclasine 6-METHOXY-3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE 6,7-DIMETHOXY-3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE 6-HYDROXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE 7,8-DIHYDRO-[1,3]DIOXOLO[4,5-G]ISOQUINOLIN-5(6H)-ONE 6,7-DIHYDROXY-3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE AKOS 236-23 AKOS 237-34 AKOS 214-22 AKOS 214-30 AKOS 214-58 6-METHOXY-2-(3-METHOXY-PHENYL)-3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE 2,2,2-TRIFLUORO-N-(5-OXO-5,6,7,8-TETRAHYDRO[1,3]DIOXOLO[4,5-G]ISOQUINOLIN-8-YL)ACETAMIDE N-(6,7-DIMETHOXY-1-OXO-1,2,3,4-TETRAHYDRO-4-ISOQUINOLINYL)-2,2,2-TRIFLUOROACETAMIDE 6-METHOXY-2-PHENYL-3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE AKOS 233-98 AKOS 213-63 8-AMINO-7,8-DIHYDRO-6H-[1,3]DIOXOLO[4,5-G]ISOQUINOLIN-5-ONE HCL

6-HYDROXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE

6-Hydroxy-3,4-dihydro-1(2H)-isoquinolinone ,97%

6-hydroxy-1,2,3,4-tetrahydroisoquinolin-1-one

1(2H)-Isoquinolinone,3,4-dihydro-6-hydroxy-

3,4-Dihydro-6-hydroxyisoquinolin-1(2H)-one

3,4-Dihydro-6-hydroxy-1(2H)-isoquinolinone

6-Hydroxy-3,4-dihydro-1-oxo-2(1H)-isoquinoline

6-Hydroxy-2- Oxo-1,2,3,4-Tetrahydroquinolene

22245-98-3