ChemicalBook > CAS DataBase List > 4,5-Dihydrocyclopenta[b]thiophen-6-one

4,5-Dihydrocyclopenta[b]thiophen-6-one

Product Name
4,5-Dihydrocyclopenta[b]thiophen-6-one
CAS No.
5650-52-2
Chemical Name
4,5-Dihydrocyclopenta[b]thiophen-6-one
Synonyms
4,5-dihydro-6H-cyclopenta[b]thiophen-6-one;5-CHLORO-2,3-DIMET...;4H-Cyclopenta[b]thiophen-6(5H);4H-cyclopenta[b]thiophen-6(5H)-one;4H,5H,6H-cyclopenta[b]thiophen-6-one;4,5-Dihydrocyclopenta[b]thiophen-6-one;6H-Cyclopenta[b]thiophen-6-one, 4,5-dihydro-;5-bromo-N-(2-furanylmethyl)-2-methylbenzenesulfonamide
CBNumber
CB11512529
Molecular Formula
C7H6OS
Formula Weight
138.19
MOL File
5650-52-2.mol
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4,5-Dihydrocyclopenta[b]thiophen-6-one Property

Melting point:
90-91 °C
Boiling point:
239.6±9.0 °C(Predicted)
Density 
1.322±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
Appearance
Light yellow to yellow Solid
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Safety

HS Code 
2934999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
C993173
Product name
4H-Cyclopenta[b]thiophen-6(5H)-one
Packaging
50mg
Price
$45
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC154203
Product name
4H-Cyclopenta[b]thiophen-6(5H)-one
Packaging
50mg
Price
$100
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC154203
Product name
4H-Cyclopenta[b]thiophen-6(5H)-one
Packaging
100mg
Price
$150
Updated
2021/12/16
Matrix Scientific
Product number
074530
Product name
4H-Cyclopenta[b]thiophen-6(5H)-one
Purity
95+%
Packaging
250mg
Price
$184
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC154203
Product name
4H-Cyclopenta[b]thiophen-6(5H)-one
Packaging
250mg
Price
$240
Updated
2021/12/16
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4,5-Dihydrocyclopenta[b]thiophen-6-one Chemical Properties,Usage,Production

Synthesis

16378-06-6

5650-52-2

To a suspension of phosphorus pentoxide (P2O5, 25.4 g, 179.0 mmol) in methanesulfonic acid (100 mL) was added 3-(thiophen-3-yl)propionic acid (5.0 g, 32.0 mmol) and the reaction mixture was stirred for 1 hour at room temperature. Upon completion of the reaction, the reaction mixture was concentrated under reduced pressure and the residue was purified by fast column chromatography (eluent: 20-30% ethyl acetate/hexane) to afford 4,5-dihydropenta[B]thiophen-6-one (1.34 g, 30% yield) as a brown solid. The structure of the product was confirmed by 1H NMR (300 MHz, MeOH): δ 8.14 (d, J = 4.8 Hz, 1H), 7.17 (d, J = 4.8 Hz, 1H), 2.94-3.15 (m, 4H); mass spectra (EI) m/z = 139.2 [M + 1]+.

References

[1] European Journal of Organic Chemistry, 2004, # 21, p. 4442 - 4451
[2] Tetrahedron, 1997, vol. 53, # 12, p. 4239 - 4246
[3] Patent: US2012/225857, 2012, A1. Location in patent: Page/Page column 16
[4] Journal of Organic Chemistry, 1997, vol. 62, # 8, p. 2401 - 2408
[5] Journal of the Chemical Society, Chemical Communications, 1994, # 19, p. 2249 - 2250

4,5-Dihydrocyclopenta[b]thiophen-6-one Preparation Products And Raw materials

Raw materials

Preparation Products

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4,5-Dihydrocyclopenta[b]thiophen-6-one Suppliers

China 62 China Hong Kong 1 India 1 United Kingdom 1 United States 6 Global 71
Shandong Mailifeng Biotechnology Co., Ltd.
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18032852911
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China
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Capot Chemical Co., Ltd
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+86 (0) 571 85 58 67 18
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0086-571-85864795
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China
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Tetranov Biopharm
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13526569071
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China Langchem Inc.
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0086-21-58956006
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0086-21-58956100
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China
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18270980682
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021 51613951
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mlcheng@sunwaypharm.cn
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Tianjin Derchemist Science & Technology Co., Ltd.
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22-58627059 13920586291
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zdcomcon@126.com
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9ding chemical ( Shanghai) Limited
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Shanghai Witofly Chemical Co.,Ltd
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Zhengzhou HSH Science & Technology Co., Ltd.
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0371-55932928 18937192232
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0086-0371-55932928
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1282296214@qq.com
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China
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View Lastest Price from 4,5-Dihydrocyclopenta[b]thiophen-6-one manufacturers

Career Henan Chemical Co
Product
4,5-Dihydrocyclopenta[b]thiophen-6-one 5650-52-2
Price
US $1.00/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
100kg
Release date
2020-01-14

5650-52-2, 4,5-Dihydrocyclopenta[b]thiophen-6-oneRelated Search:

4,5-Dihydrocyclopenta[b]thiophen-6-one 4-AMINO-4,5-DIHYDRO-6H-CYCLOPENTA[B]THIOPHEN-6-ONE HYDROCHLORIDE 2,2,2-TRIFLUORO-N-(6-OXO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHEN-4-YL)ACETAMIDE 2,4-DICHLORO-N-(6-OXO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHEN-4-YL)BENZENECARBOXAMIDE N-(5-BROMO-6-OXO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHEN-4-YL)-2,2,2-TRIFLUOROACETAMIDE N-(5-[(Z)-(DIMETHYLAMINO)METHYLIDENE]-6-OXO-4,6-DIHYDRO-5H-CYCLOPENTA[B]THIOPHEN-4-YL)-2,2,2-TRIFLUOROACETAMIDE AKOS 91683 N-(6-OXO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHEN-4-YL)-3-(TRIFLUOROMETHYL)BENZENECARBOXAMIDE AKOS 91897 N-(6-OXO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHEN-4-YL)CYCLOHEXANECARBOXAMIDE N-(6-OXO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHEN-4-YL)-2-THIOPHENESULFONAMIDE AKOS 91899 N-(5-[(Z)-(3,5-DIMETHOXYANILINO)METHYLIDENE]-6-OXO-4,6-DIHYDRO-5H-CYCLOPENTA[B]THIOPHEN-4-YL)-2,2,2-TRIFLUOROACETAMIDE 4-METHOXY-N-(6-OXO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHEN-4-YL)BENZENESULFONAMIDE 2-NITRO-N-(6-OXO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHEN-4-YL)BENZENESULFONAMIDE N-(6-OXO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHEN-4-YL)-2-FURAMIDE AKOS 91689 1-(2,2,2-TRIFLUOROACETYL)-1A,5B-DIHYDROTHIENO[2',3':4,5]CYCLOPENTA[1,2-B]AZIREN-2(1H)-ONE

  • 4,5-Dihydrocyclopenta[b]thiophen-6-one
  • 4H-cyclopenta[b]thiophen-6(5H)-one
  • 4,5-dihydro-6H-cyclopenta[b]thiophen-6-one
  • 4H,5H,6H-cyclopenta[b]thiophen-6-one
  • 4H-Cyclopenta[b]thiophen-6(5H)
  • 5-CHLORO-2,3-DIMET...
  • 5-bromo-N-(2-furanylmethyl)-2-methylbenzenesulfonamide
  • 6H-Cyclopenta[b]thiophen-6-one, 4,5-dihydro-
  • 5650-52-2
  • API intermediates