1H-pyrazolo[4,3-c]pyridine-3-carboxylic acid
Application- Product Name
- 1H-pyrazolo[4,3-c]pyridine-3-carboxylic acid
- CAS No.
- 932702-11-9
- Chemical Name
- 1H-pyrazolo[4,3-c]pyridine-3-carboxylic acid
- Synonyms
- 1H-pyrazolo[4,3-c]pyridine-3-carboxylic acid;1H-pyrazolo[4,3-c]pyridine-3-carboxylic acid ISO 9001：2015 REACH
- CBNumber
- CB11515757
- Molecular Formula
- C7H5N3O2
- Formula Weight
- 163.13
- MOL File
- 932702-11-9.mol
1H-pyrazolo[4,3-c]pyridine-3-carboxylic acid Property
- Boiling point:
- 501.7±30.0 °C(Predicted)
- Density
- 1.617
- storage temp.
- 2-8°C
- pka
- 1.54±0.30(Predicted)
- Appearance
- Off-white to yellow Solid
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- OR921183
- Product name
- 1H-Pyrazolo[4,3-c]pyridine-3-carboxylicacid
- Purity
- 95%
- Packaging
- 100mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- OR921183
- Product name
- 1H-Pyrazolo[4,3-c]pyridine-3-carboxylicacid
- Purity
- 95%
- Packaging
- 250mg
- Price
- $185
- Updated
- 2021/12/16
- Product number
- W9600
- Product name
- 1H-pyrazolo[4,3-c]pyridine-3-carboxylicacid
- Packaging
- 250mg
- Price
- $254
- Updated
- 2021/12/16
- Product number
- 073844
- Product name
- 1H-Pyrazolo[4,3-c]pyridine-3-carboxylic acid
- Purity
- 95+%
- Packaging
- 500mg
- Price
- $260
- Updated
- 2021/12/16
- Product number
- 073844
- Product name
- 1H-Pyrazolo[4,3-c]pyridine-3-carboxylic acid
- Purity
- 95+%
- Packaging
- 1g
- Price
- $400
- Updated
- 2021/12/16
1H-pyrazolo[4,3-c]pyridine-3-carboxylic acid Chemical Properties,Usage,Production
Application
1H-pyrazolo[4,3-C]pyridine-3-carboxylic acid is an intermediate in organic synthesis and pharmaceutical research and development, and can be used in laboratory organic synthesis and chemical and pharmaceutical synthesis processes.
Synthesis
932702-12-0
932702-11-9
936923-48-7
The general procedure for the synthesis of 1H-pyrazolo[4,3-c]pyridine-3-carboxylic acid and compound (CAS: 936923-48-7) using compound (CAS: 932702-12-0) as starting material was as follows: in a microwave reaction vessel, N,N-diisopropyl-1H-pyrazolo[4,3-c]pyridine-3-carboxamide (0.800 g. 0.00325 mol) was mixed with 10 M aqueous hydrogen chloride solution (3.00 mL). The mixture was heated at 120 °C for 10 min. Heating at high absorbance settings is required to avoid pressure buildup. After completion of the reaction, the reaction mixture was diluted with water and neutralized with 3 N sodium hydroxide solution. The resulting white precipitate was collected and analyzed and found to be a mixture of 1H-pyrazolo[4,3-c]pyridine-3-carboxylic acid (47%) and monoisopropylamide (25%). The mixture could be used in subsequent steps without further purification.
References
[1] Patent: US2007/78147, 2007, A1. Location in patent: Page/Page column 69
[2] Patent: WO2007/56582, 2007, A1. Location in patent: Page/Page column 76
1H-pyrazolo[4,3-c]pyridine-3-carboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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