befiradol

Product Name: befiradol
CAS No.: 208110-64-9
Chemical Name: befiradol
Synonyms: F 13640;NLX 112);befiradol;Unii-rat9oha1yh;Befiradol (F 13640;NLX-112 hydrochloride;1-(3-Chloro-4-fluorobenzoyl)-4-fluoro-N-[(5-methyl-2-pyridinyl)methyl]-4-piperidinemethanamine;(3-chloro-4-fluorophenyl)-[4-fluoro-4-[[(5-methylpyridin-2-yl)methylamino]methyl]piperidin-1-yl]methanone;Methanone, (3-chloro-4-fluorophenyl)[4-fluoro-4-[[[(5-methyl-2-pyridinyl)methyl]amino]methyl]-1-piperidinyl]-;Befiradol/NLX-112/F13640/(3-Chloro-4-fluorophenyl)(4-fluoro-4-((((5-methylpyridin-2-yl)methyl)amino)methyl)piperidin-1-yl)methanone
CBNumber: CB11518495
Molecular Formula: C20H22ClF2N3O
Formula Weight: 393.86
MOL File: 208110-64-9.mol

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befiradol Property

Boiling point:: 536.9±50.0 °C(Predicted)
Density: 1.30
storage temp.: Store at -20°C
solubility: Soluble in DMSO
pka: 8.01±0.20(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML2324
Product name: NLX-112hydrochloride
Purity: ≥98%(HPLC)
Packaging: 5mg
Price: $132
Updated: 2025/07/31

Sigma-Aldrich

Product number: SML2324
Product name: NLX-112hydrochloride
Purity: ≥98%(HPLC)
Packaging: 25mg
Price: $528
Updated: 2025/07/31

American Custom Chemicals Corporation

Product number: API0026899
Product name: BEFIRADOL
Purity: 95.00%
Packaging: 0.5MG
Price: $632.5
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0026899
Product name: BEFIRADOL
Purity: 95.00%
Packaging: 1MG
Price: $721.88
Updated: 2021/12/16

DC Chemicals

Product number: DC21007
Product name: Befiradol
Purity: >98%
Packaging: 1g
Price: $2000
Updated: 2021/12/16

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befiradol Chemical Properties,Usage,Production

Uses

Befiradol (NLX-112) is a selective 5-HT1A receptor agonist.

Biological Activity

NLX-112 (also known as befiradol or F13640) is a highly selective 5-HT1A receptor full agonist with >1000-fold selectivity compared to other types of receptors. It has been investigated for the treatment of Parkinsonμs disease patients who exhibit L-DOPA-induced dyskinesia

IC 50

5-HT_1A Receptor

References

[1] Lladó-Pelfort L, et al. In vivo electrophysiological and neurochemical effects of the selective 5-HT1A receptor agonist, F13640, at pre- and postsynaptic 5-HT1A receptors in the rat. Psychopharmacology (Berl). 2012 May;221(2):261-72. DOI:10.1007/s00213-011-2569-9

befiradol Preparation Products And Raw materials

Raw materials

Preparation Products

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befiradol Suppliers

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208110-64-9, befiradolRelated Search:

N-(4-FLUOROBENZOYL)PIPERIDINE (1-Benzyl-4-piperidinyl)methylamine 4-FLUOROPIPERIDINE HYDROCHLORIDE 3-Chloro-4-fluorobenzylamine 3-CHLORO-4-FLUOROBENZAMIDE 1-(1-BENZYLPIPERIDIN-4-YL)-N-METHYLMETHANAMINE OTAVA-BB 1127481 4-FLUOROPIPERIDINE befiradol

befiradol

1-(3-Chloro-4-fluorobenzoyl)-4-fluoro-N-[(5-methyl-2-pyridinyl)methyl]-4-piperidinemethanamine

Unii-rat9oha1yh

F 13640

(3-chloro-4-fluorophenyl)-[4-fluoro-4-[[(5-methylpyridin-2-yl)methylamino]methyl]piperidin-1-yl]methanone

Befiradol (F 13640

NLX 112)

Methanone, (3-chloro-4-fluorophenyl)[4-fluoro-4-[[[(5-methyl-2-pyridinyl)methyl]amino]methyl]-1-piperidinyl]-

Befiradol/NLX-112/F13640/(3-Chloro-4-fluorophenyl)(4-fluoro-4-((((5-methylpyridin-2-yl)methyl)amino)methyl)piperidin-1-yl)methanone

NLX-112 hydrochloride

208110-64-9

C20H22ClF2N3O