Lensiprazine
- Product Name
- Lensiprazine
- CAS No.
- 327026-93-7
- Chemical Name
- Lensiprazine
- Synonyms
- SLV314;SLV-314;SLV 314;lensiprazine;(2R)-8-[4-[3-(5-fluoro-1H-indol-3-yl)propyl]piperazin-1-yl]-2-methyl-4H-1,4-benzoxazin-3-one;(2R)-8-[4-[3-(5-Fluoro-1H-indol-3-yl)propyl]-1-piperazinyl]-2-methyl-2H-1,4-benzoxazin-3(4H)-one;2H-1,4-Benzoxazin-3(4H)-one, 8-[4-[3-(5-fluoro-1H-indol-3-yl)propyl]-1-piperazinyl]-2-methyl-, (2R)-;(R)-8-(4-(3-(5-fluoro-1H-indol-3-yl)propyl)piperazin-1-yl)-2-methyl-2H-benzo[b][1,4]oxazin-3(4H)-one
- CBNumber
- CB11518516
- Molecular Formula
- C24H27FN4O2
- Formula Weight
- 422.5
- MOL File
- 327026-93-7.mol
Lensiprazine Property
- Boiling point:
- 668.5±55.0 °C(Predicted)
- Density
- 1.262
- pka
- 12.51±0.40(Predicted)
N-Bromosuccinimide Price
- Product number
- API0013978
- Product name
- LENSIPRAZINE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $634.25
- Updated
- 2021/12/16
- Product number
- API0013978
- Product name
- LENSIPRAZINE
- Purity
- 95.00%
- Packaging
- 2.5G
- Price
- $824.49
- Updated
- 2021/12/16
- Product number
- API0013978
- Product name
- LENSIPRAZINE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $960.31
- Updated
- 2021/12/16
Lensiprazine Chemical Properties,Usage,Production
Uses
Lensiprazine is a potent dopamine D2 receptor (D2R) antagonist that acts as a serotonin reuptake inhibitor. Lensiprazine can be used to study bipolar disorder and schizophrenia[1][2][3].
References
[1] Bollu R, et al. Potential anti-proliferative agents from 1, 4-benzoxazinone-quinazolin-4 (3H)-one templates[J]. Bioorganic & Medicinal Chemistry Letters, 2017, 27(24): 5481-5484. DOI:10.1016/j.bmcl.2017.10.044
[2] Lange J H M, et al. Principal component analysis differentiates the receptor binding profiles of three antipsychotic drug candidates from current antipsychotic drugs[J]. Journal of medicinal chemistry, 2007, 50(21): 5103-5108. DOI:10.1021/jm070516u
[3] Rauly-Lestienne I, et al. Differential profile of typical, atypical and third generation antipsychotics at human 5-HT 7a receptors coupled to adenylyl cyclase: detection of agonist and inverse agonist properties[J]. Naunyn-Schmiedeberg's archives of pharmacology, 2007, 376: 93-105. DOI:10.1007/s00210-007-0182-6
Lensiprazine Preparation Products And Raw materials
Raw materials
Preparation Products
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