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1-ethyl-1H-pyrazol-4-amine

Product Name
1-ethyl-1H-pyrazol-4-amine
CAS No.
876343-24-7
Chemical Name
1-ethyl-1H-pyrazol-4-amine
Synonyms
1-ethylpyrazol-4-amine;4-Amino-1-ethylpyrazole;1-ethyl-1H-pyrazol-4-amine;4-Amino-1-ethyl-1H-pyrazole;1H-Pyrazol-4-amine, 1-ethyl-;1-ethyl-1H-pyrazol-4-amine hydrochloride;1-ethyl-1H-pyrazol-4-amine(SALTDATA: HCl)
CBNumber
CB11532949
Molecular Formula
C5H9N3
Formula Weight
111.15
MOL File
876343-24-7.mol
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1-ethyl-1H-pyrazol-4-amine Property

Boiling point:
238.6±13.0 °C(Predicted)
Density 
1.16±0.1 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
3.72±0.10(Predicted)
CAS DataBase Reference
876343-24-7
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Safety

HazardClass 
IRRITANT
HS Code 
2933199090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

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N-Bromosuccinimide Price

AK Scientific
Product number
3909AC
Product name
1-Ethyl-1H-pyrazol-4-amine
Packaging
250mg
Price
$103
Updated
2021/12/16
AK Scientific
Product number
3909AC
Product name
1-Ethyl-1H-pyrazol-4-amine
Packaging
1g
Price
$136
Updated
2021/12/16
BroadPharm
Product number
BP-21178
Product name
1-ETHYL-1H-PYRAZOL-4-AMINE
Packaging
500mg
Price
$150
Updated
2021/12/16
Matrix Scientific
Product number
034033
Product name
1-Ethyl-1H-pyrazol-4-ylamine hydrochloride
Packaging
500mg
Price
$195
Updated
2021/12/16
Apolloscientific
Product number
OR110643
Product name
4-Amino-1-ethyl-1H-pyrazole
Packaging
1g
Price
$225
Updated
2021/12/16
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1-ethyl-1H-pyrazol-4-amine Chemical Properties,Usage,Production

Uses

1-ethyl-1H-pyrazol-4-amine can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

Synthesis


General Procedure for the Synthesis of 4-Amino-l-N-alkylated-pyrazolesA solution of 4-nitropyrazole (300mg, 2.65mmol), potassium carbonate (2eq) and the alkylating reagent (l .leq) in acetonitrile (lOmL) was heated at 60??C for 18h. After cooling to rt the mixture was diluted with EtOAc and washed with water. The organic phase was collected, dried (MgS04) and concentrated in vacuo. The crude residue was dissolved in methanol (lOmL), palladium on carbon (50mg) was added and the reaction was stirred under a balloon of hydrogen for 18h. The resulting mixture was filtered through Celite and the filtrate concentrated in vacuo to give the desired product. Procedure B:Example 11: 2-((6-( 1 -Ethyl- 1 H-pyrazo 1-4-ylamino)- 1 H-pyrazo lo [3 ,4-d]pyrimidin- 1 -yl) methyl)benzonitrileThe following compound was made according to the procedure in Example 1, using 1-ethyl- lH-pyrazo 1-4-amine. 1 -ethyl- lH-pyrazol-4-amine was prepared by Procedure A using ethyl iodide as alkylating agent: 1H NMR (d6-DMSO) |? 9.94 (s, 1H), 8.94 (s, 1H), 8.10 (s, 2H), 7.91 (dd, 1H), 7.66 (td, 1H), 7.49-7.53 (m, 2H), 7.35-7.37 (m, 1H), 5.76 (s, 2H), 4.11 (q, 2H), 1.35 (t, 3H); LC-MS method B, (ES+) 345.1, RT = 8.58min.

1-ethyl-1H-pyrazol-4-amine Preparation Products And Raw materials

Raw materials

Preparation Products

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1-ethyl-1H-pyrazol-4-amine Suppliers

876343-24-7, 1-ethyl-1H-pyrazol-4-amineRelated Search:


  • 1-ethyl-1H-pyrazol-4-amine
  • 1-ethyl-1H-pyrazol-4-amine(SALTDATA: HCl)
  • 4-Amino-1-ethylpyrazole
  • 1-ethyl-1H-pyrazol-4-amine hydrochloride
  • 4-Amino-1-ethyl-1H-pyrazole
  • 1-ethylpyrazol-4-amine
  • 1H-Pyrazol-4-amine, 1-ethyl-
  • 876343-24-7