ChemicalBook > CAS DataBase List > 3-(BENZYLAMINO)PROPIONITRILE

3-(BENZYLAMINO)PROPIONITRILE

Product Name
3-(BENZYLAMINO)PROPIONITRILE
CAS No.
706-03-6
Chemical Name
3-(BENZYLAMINO)PROPIONITRILE
Synonyms
β-(Benzylamino)propionitrile;3-(BENZYLAMINO)PROPIONITRILE;3-(Benzylamino)propionitrile 97%;3-(BENZYLAMINO)PROPIONITRILE, 97+%;N-(2-Cyanoethyl)benzenemethanamine;3-[(Phenylmethyl)amino]propanenitrile;Propanenitrile, 3-[(phenylmethyl)amino]-
CBNumber
CB1159680
Molecular Formula
C10H12N2
Formula Weight
160.22
MOL File
706-03-6.mol
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3-(BENZYLAMINO)PROPIONITRILE Property

Melting point:
70 °C
Boiling point:
276.13°C (rough estimate)
Density 
1.024 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.5308(lit.)
Flash point:
>230 °F
storage temp. 
Refrigerator
solubility 
Soluble in DMSO.
form 
Liquid
pka
7.29±0.19(Predicted)
color 
Clear Colorless
Specific Gravity
1.024
CAS DataBase Reference
706-03-6
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
20/21/22-36/37/38
Safety Statements 
26-37/39
RIDADR 
UN3276
WGK Germany 
3
HazardClass 
6.1
PackingGroup 
III
HS Code 
29269095
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
185167
Product name
3-(Benzylamino)propionitrile
Purity
97%
Packaging
25g
Price
$98.2
Updated
2023/06/20
Sigma-Aldrich
Product number
185167
Product name
3-(Benzylamino)propionitrile
Purity
97%
Packaging
100g
Price
$256
Updated
2023/06/20
Alfa Aesar
Product number
041949
Product name
3-(Benzylamino)propionitrile, 97+%
Packaging
5g
Price
$23.65
Updated
2024/03/01
Alfa Aesar
Product number
041949
Product name
3-(Benzylamino)propionitrile, 97+%
Packaging
25g
Price
$72.65
Updated
2024/03/01
Alfa Aesar
Product number
041949
Product name
3-(Benzylamino)propionitrile, 97+%
Packaging
100g
Price
$227.65
Updated
2024/03/01
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3-(BENZYLAMINO)PROPIONITRILE Chemical Properties,Usage,Production

Chemical Properties

CLEAR COLOURLESS LIQUID

Uses

3-(Benzylamino)propionitrile was used as starting reagent in the synthesis of:

  • (3R,4S)-1-benzyl-4-phenylpyrrolidine-3-carboxylic acid, key chiral building block for synthesis of biologically active compounds
  • 1-{[benzyl-(2-cyano-ethyl)-amino]-methyl}-5-methyl-1H-pyrazole-3-carboxylic acid ethyl ester
  • 3-[benzyl-(3,5-dimethyl-pyrazol-1-ylmethyl)-amino]-propionitrile

Uses

3-(BenzylaMino)propionitrile is used in the michael addition of primary and secondary amines to acrylonitrile catalyzed by lipases.

Application

3-(Benzylamino)propionitrile was used as starting reagent in the synthesis of:
(3R,4S)-1-benzyl-4-phenylpyrrolidine-3-carboxylic acid, key chiral building block for synthesis of biologically active compounds
1-{[benzyl-(2-cyano-ethyl)-amino]-methyl}-5-methyl-1H-pyrazole-3-carboxylic acid ethyl ester
3-[benzyl-(3,5-dimethyl-pyrazol-1-ylmethyl)-amino]-propionitrile

General Description

3-(Benzylamino)propionitrile undergoes aza-type Michael reaction with 1-hydroxymethyl-5-methyl-1H-pyrazole-3-carboxylic acid ethyl ester under mild conditions.

3-(BENZYLAMINO)PROPIONITRILE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-(BENZYLAMINO)PROPIONITRILE Suppliers

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706-03-6, 3-(BENZYLAMINO)PROPIONITRILERelated Search:

3-(BENZYLAMINO)PROPIONITRILE 1,3-DIBENZYL-5-CYANOHEXAHYDROPYRIMIDINE 1-Benzhydrylazetane-3-carbonitrile 3-(4-CHLORO-BENZYLAMINO)-PROPIONITRILE Propionitrile 6-(4-FLUOROPHENYL)-1,2-DIHYDRO-2-OXOPYRIDINE-3-CARBONITRILE N-(2-CYANOETHYL)-PHTHALIMIDE 2-OXO-6-PHENYL-1,2-DIHYDRO-3-PYRIDINECARBONITRILE 6-(4-CHLOROPHENYL)-1-(3,4-DICHLOROBENZYL)-2-OXO-1,2-DIHYDRO-3-PYRIDINECARBONITRILE 4-(METHYLTHIO)-6-OXO-2-PHENYL-1,6-DIHYDROPYRIMIDINE-5-CARBONITRILE 1-(3-CHLOROBENZYL)-2-OXO-6-PHENYL-1,2-DIHYDRO-3-PYRIDINECARBONITRILE 1-(3,4-DICHLOROBENZYL)-6-(4-FLUOROPHENYL)-2-OXO-1,2-DIHYDRO-3-PYRIDINECARBONITRILE 1-[[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL](METHYL)AMINO]-3-(4-FLUOROBENZYL)-2,4-DIOXO-1,2,3,4-TETRAHYDRO-5-PYRIMIDINECARBONITRILE N1,N1-DI(2-CYANOETHYL)-4-CHLORO-3-NITROBENZAMIDE 6-(4-FLUOROPHENYL)-2-OXO-1-[3-(TRIFLUOROMETHYL)BENZYL]-1,2-DIHYDRO-3-PYRIDINECARBONITRILE 1-(2-CHLOROBENZYL)-2-OXO-6-PHENYL-1,2-DIHYDRO-3-PYRIDINECARBONITRILE 1-(4-CHLOROBENZYL)-6-(DIMETHOXYMETHYL)-2-OXO-1,2-DIHYDRO-3-PYRIDINECARBONITRILE 1-METHYL-4-(METHYLSULFANYL)-2-OXO-6-PHENYL-1,2-DIHYDRO-3-PYRIDINECARBONITRILE

  • 3-(BENZYLAMINO)PROPIONITRILE
  • 3-(BENZYLAMINO)PROPIONITRILE, 97+%
  • 3-[(Phenylmethyl)amino]propanenitrile
  • N-(2-Cyanoethyl)benzenemethanamine
  • β-(Benzylamino)propionitrile
  • 3-(Benzylamino)propionitrile 97%
  • Propanenitrile, 3-[(phenylmethyl)amino]-
  • 706-03-6
  • C10H12N2
  • C6H5CH2NHCH2CH2CN
  • Nitrogen Compounds
  • Organic Building Blocks
  • Cyanides/Nitriles
  • Building Blocks
  • C10 to C27
  • C10 to C27
  • Cyanides/Nitriles
  • Nitrogen Compounds