OROTIDINE

Product Name: OROTIDINE
CAS No.: 314-50-1
Chemical Name: OROTIDINE
Synonyms: OROTIDINE;Orotidine ,98%;6-Carboxyuridine;URIDIN-6-CARBOXYLIC ACID;URIDINE-6-CARBOXYLIC ACID;orotidine free acid approx. 90%;Orotidine (Uridine-6-carboxylic acid);1,2,3,6-Tetrahydro-2,6-dioxo-3-β-D-ribofuranosyl-4-pyrimidinecarboxylic acid;4-Pyrimidinecarboxylicacid, 1,2,3,6-tetrahydro-2,6-dioxo-3-b-D-ribofuranosyl-;4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-3-β-D-ribofuranosyl-
CBNumber: CB1164936
Molecular Formula: C10H12N2O8
Formula Weight: 288.21
MOL File: 314-50-1.mol

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OROTIDINE Property

Melting point:: >400 °C
Density: 1.847±0.06 g/cm3(Predicted)
storage temp.: −20°C
solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form: Solid
pka: 2.62±0.20(Predicted)
color: White to Off-White

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Safety

WGK Germany: 3
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: O691520
Product name: Orotidine
Packaging: 1mg
Price: $95
Updated: 2021/12/16

Usbiological

Product number: 296366
Product name: Orotidine
Packaging: 1mg
Price: $531
Updated: 2021/12/16

TRC

Product number: O691520
Product name: Orotidine
Packaging: 25mg
Price: $1620
Updated: 2021/12/16

Biosynth Carbosynth

Product number: NO08048
Product name: Orotidine
Packaging: 25mg
Price: $1875
Updated: 2021/12/16

Biosynth Carbosynth

Product number: NO08048
Product name: Orotidine
Packaging: 0.0025g
Price: $90
Updated: 2021/12/16

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OROTIDINE Chemical Properties,Usage,Production

Uses

Orotidine is a metabolite of Orotic Acid (O691500); a compound used in the preparation of therapeutic agents for chronic obstructive pulmonary disease (COPD) treatment.

Definition

ChEBI: A nucleoside formed by attaching orotic acid to a ribose ring via a beta1N(1)-glycosidic bond.

Enzyme inhibitor

This water-soluble ribonucleoside (FWfree-acid = 288.21 g/mol; CAS 314-50- 1; lmax of 267 nm in 0.1 N HCl (e = 9570 cm–1M–1; another report lists 9800) and 265 nm in 0.1 N methanolic NaOH (e = 8960 cm–1M–1; another report lists 7800)), first observed in Neurospora crassa, is also foound in the urine of cancer patients treated with 6-azauridine, Orotidine is most likely formed from OMP, its 5’-monophosphate ester and the direct precursor of UMP. Orotidine is readily hydrolyzed in dilute mineral acids. Target(s): orotate phosphoribosyltransferase; orotidine-5’-phosphate decarboxylase.

OROTIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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OROTIDINE Suppliers

China 29 Germany 1 India 1 Switzerland 1 United Kingdom 5 United States 10 Global 47

J & K SCIENTIFIC LTD.

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314-50-1, OROTIDINERelated Search:

OROTIDINE-5'-MONOPHOSPHATE*PYROPHOSPHORYLASE FROM BR Orotidine-5'-Phosphate Decarboxylase OROTIDINE-5'-MONOPHOSPHATE*DECARBOXYLASE PURIFIED FR orotidine 5'-monophosphate OROTIDINE-5'-PHOSPHATE*PYROPHOSPHORYLASE AND OROTID OROTIC ACID MONOHYDRATE OROTIDINE 2-(2-METHYL-THIAZOL-4-YL)-PHENOL 6-FORMYL-URACIL MONOHYDRATE 6-(HYDROXYMETHYL)URACIL N-N-bis(2-hydroxyethyl)formamide orotidine 5'-monophosphate trisodium salt,OROTIDINE 5'-MONOPHOSPHATE SODIUM SALT,orotidine 5'-monophosphate trisodium acrylic acid, compound with 2-aminoethanol (1:1)

OROTIDINE

URIDINE-6-CARBOXYLIC ACID

URIDIN-6-CARBOXYLIC ACID

Orotidine (Uridine-6-carboxylic acid)

1,2,3,6-Tetrahydro-2,6-dioxo-3-β-D-ribofuranosyl-4-pyrimidinecarboxylic acid

6-Carboxyuridine

3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl]-2,6-diketo-pyrimidine-4-carboxylic acid

Orotidine ,98%

orotidine free acid approx. 90%

3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,6-dioxopyrimidine-4-carboxylic acid

4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-3-β-D-ribofuranosyl-

4-Pyrimidinecarboxylicacid, 1,2,3,6-tetrahydro-2,6-dioxo-3-b-D-ribofuranosyl-

3-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid

314-50-1

C10H13N2O11P

C10H12N2O8

Biochemicals and Reagents

BioChemical

Nucleosides, Nucleotides, Oligonucleotides

Nucleoside Analogs